WormBase Tree Display for Gene: WBGene00006811
expand all nodes | collapse all nodes | view schema
WBGene00006811 | SMap | S_parent | Sequence | CHROMOSOME_III | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | unc | ||||||
Reference_allele | WBVar00143719 | ||||||
Allele (224) | |||||||
Legacy_information | e1068 : irregular movement somewhat sluggish. ES2 ME3. NA4 (e1031 etc.). | ||||||
See also e1030, e1031, e1068, e1291, e1510 | |||||||
[C.elegansII] e1068 : irregular movement, somewhat sluggish ("fainter"); hypersensitive to volatile anaesthetics.ES2 ME3. OA>5: e1031, e1291, e1510, ec1 etc. [Sedensky and Meneely 1987; Morgan et al. 1991; CW] | |||||||
Strain (12) | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (11) | |||||||
Ortholog (43) | |||||||
Structured_description | Concise_description | unc-79 encodes a novel, conserved protein; unc-79 functions in a pathway with unc-77 and nca-2, which encode alpha-1 subunits of voltage-insensitive cation leak channels, to regulate locomotion and the response to specific volatile anesthetics; unc-79 exerts its effects on these processes, at least in part, by regulating the levels of UNC-77 and NCA-2 proteins; an unc-79::gfp reporter is expressed in the nervous system in ventral nerve cord neurons in L2 and L3 larvae and in one or two head neurons in adults; UNC-79 exhibits a punctate staining pattern in ventral nerve cord and nerve ring processes, and this staining is dependent upon UNC-80, UNC-77, and NCA-2. | Paper_evidence | WBPaper00001281 | |||
WBPaper00030757 | |||||||
WBPaper00031592 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson324 | |||||||
Date_last_updated | 22 Jun 2010 00:00:00 | ||||||
Automated_description | Involved in several processes, including response to anesthetic; response to ethanol; and response to toluene. Located in axon. Expressed in head neurons; nerve ring; nervous system; tail neurons; and ventral cord neurons. Used to study alcohol use disorder. Is an ortholog of human UNC79 (unc-79 homolog, NALCN channel complex subunit). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Experimental_model | DOID:1574 | Homo sapiens | Paper_evidence | WBPaper00002358 | ||
Curator_confirmed | WBPerson324 | ||||||
Date_last_updated | 29 Apr 2019 00:00:00 | ||||||
Models_disease_in_annotation | WBDOannot00000654 | ||||||
Molecular_info | Corresponding_CDS | E03A3.6a | |||||
E03A3.6b | |||||||
Corresponding_CDS_history | E03A3.6:wp79 | ||||||
E03A3.6:wp179 | |||||||
E03A3.6:wp183 | |||||||
E03A3.6a:wp200 | |||||||
Corresponding_transcript | E03A3.6a.1 | ||||||
E03A3.6b.1 | |||||||
E03A3.6b.2 | |||||||
E03A3.6b.3 | |||||||
Other_sequence (50) | |||||||
Associated_feature (23) | |||||||
Experimental_info | RNAi_result (26) | ||||||
Expr_pattern | Expr8062 | ||||||
Expr8326 | |||||||
Expr16167 | |||||||
Expr1027571 | |||||||
Expr1032877 | |||||||
Expr1147615 | |||||||
Expr2017908 | |||||||
Expr2036044 | |||||||
Drives_construct | WBCnstr00013262 | ||||||
WBCnstr00017149 | |||||||
WBCnstr00042791 | |||||||
Construct_product | WBCnstr00017149 | ||||||
Antibody | WBAntibody00001385 | ||||||
WBAntibody00002202 | |||||||
Microarray_results (50) | |||||||
Expression_cluster (204) | |||||||
Interaction (66) | |||||||
Map_info | Map | III | Position | -3.89038 | Error | 0.022171 | |
Well_ordered | |||||||
Positive | Inside_rearr | nDf10 | |||||
nDf11 | |||||||
nDf14 | |||||||
Positive_clone | E03A3 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
Mapping_data | 2_point (3) | ||||||
Multi_point (30) | |||||||
Pos_neg_data (14) | |||||||
Reference (74) | |||||||
Method | Gene |