| WBGene00006788 | SMap | S_parent | Sequence | CHROMOSOME_II |
|---|
| Identity | Version | 1 |
| | Name | CGC_name | unc-53 | Person_evidence | WBPerson261 |
| | | Sequence_name | F45E10.1 |
| | | Molecular_name (24) |
| | | Other_name | CELE_F45E10.1 | Accession_evidence | NDB | BX284602 |
| | | Public_name | unc-53 |
| | DB_info | Database (11) |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:42 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | unc |
| | Reference_allele | WBVar00143183 |
| | Allele (424) |
| | Legacy_information | e404 : sluggish poor backing dumpyish somewhat Egl; males have abnormal bursal anatomy. ES2 ME0. NA4 (n152 n166 n569). |
| | | See also e2432, e2499, n152, n166, n569 |
| | | [C.elegansII] e404 : sluggish, poor backing, dumpyish; somewhat Egl; multiple defects in neuronal outgrowth, branching; also defects in excretory canal extension, gonad arm growth; males have abnormal bursal anatomy. ES2 ME0. OA>5: n152, n166, n569 (synergizes with sem-5(n177) to give strong Sem migration defect),e2432, e2499, etc. Null phenotype uncertain; some lethality in strong alleles. Cloned: multiple transcripts (different 5' ends); one encodes 1528 aa protein, predicted to bind actin, ATP/GTP; may interact with SEM-5. Transgene overexpression leads to extension of growth cones along a-p axis. [Hedgecock et al. 1987; Hekimi and Kershaw 1993; UG] |
| | Strain | WBStrain00026706 |
| | | WBStrain00026870 |
| | | WBStrain00032757 |
| | | WBStrain00034470 |
| | | WBStrain00034483 |
| | | WBStrain00037045 |
| | | WBStrain00004162 |
| | | WBStrain00004572 |
| | | WBStrain00005655 |
| | RNASeq_FPKM | WBls:0000002 (84) |
| | | WBls:0000003 (11) |
| | | WBls:0000004 (44) |
| | | WBls:0000006 | 0.0355104 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000006.Hermaphrodite.WBbt:0007833.SRP042619.SRX559705 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000006.Hermaphrodite.WBbt:0007833.SRP042619.SRX559706 |
| | | WBls:0000007 | 0.0370038 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0007833.SRP042619.SRX559707 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0007833.SRP042619.SRX559708 |
| | | | 0.0479057 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0004015.SRP045110.SRX666565 |
| | | | 0.0746431 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0006770.SRP045110.SRX666568 |
| | | | 0.0756852 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0004015.SRP045110.SRX666567 |
| | | | 0.130363 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0004015.SRP045110.SRX666563 |
| | | | 0.204408 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0006770.SRP045110.SRX666566 |
| | | | 0.336823 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0006770.SRP045110.SRX666564 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0004015.SRP029448.SRX343218 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0004015.SRP029448.SRX343219 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0007833.SRP029448.SRX343215 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0007833.SRP029448.SRX343216 |
| | | WBls:0000008 | 0.156622 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000008.Hermaphrodite.WBbt:0007833.SRP000401.SRX085219 |
| | | | 0.192294 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000008.Hermaphrodite.WBbt:0007833.SRP000401.SRX085220 |
| | | | 0.346662 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000008.Hermaphrodite.WBbt:0007833.SRP000401.SRX145480 |
| | | WBls:0000010 (15) |
| | | WBls:0000013 (11) |
| | | WBls:0000014 (19) |
| | | WBls:0000015 (24) |
| | | WBls:0000017 | 0.175023 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004804.SRP029448.SRX343253 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0003810.SRP029448.SRX343325 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004804.SRP029448.SRX343252 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004804.SRP029448.SRX343254 |
| | | | 26.4521 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004458.SRP029448.SRX343277 |
| | | | 27.2065 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004458.SRP029448.SRX343278 |
| | | | 36.6002 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004015.SRP029448.SRX343304 |
| | | | 41.8805 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004015.SRP029448.SRX343305 |
| | | | 6.56962 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0008115.SRP029448.SRX343342 |
| | | | 9.09011 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0003810.SRP029448.SRX343324 |
| | | WBls:0000020 (16) |
| | | WBls:0000021 (20) |
| | | WBls:0000023 | 0.621136 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000023.Hermaphrodite.WBbt:0007833.SRP015688.SRX185639 |
| | | WBls:0000024 (71) |
| | | WBls:0000027 (15) |
| | | WBls:0000031 | 12.8461 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX047470 |
| | | | 13.949 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX103277 |
| | | | 37.2022 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX103275 |
| | | | 40.3848 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX103273 |
| | | | 41.3129 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX103274 |
| | | | 44.4984 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX103276 |
| | | | 44.5242 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX008139 |
| | | WBls:0000032 | 13.2161 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP000401.SRX008138 |
| | | | 14.7033 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP000401.SRX103985 |
| | | | 15.2325 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP000401.SRX103983 |
| | | | 16.6306 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP000401.SRX103984 |
| | | | 7.59587 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP058023.SRX1019178 |
| | | | 8.59818 | From_analysis | RNASeq.elegans.WBls:0000032.control_mean |
| | | | | | RNASeq.elegans.WBls:0000032.control_median |
| | | | 9.60048 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP058023.SRX1019179 |
| | | WBls:0000035 (26) |
| | | WBls:0000038 (85) |
| | | WBls:0000041 (30) |
| | | WBls:0000052 | 13.4945 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103278 |
| | | | 13.4957 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103280 |
| | | | 14.7599 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103281 |
| | | | 16.0209 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103279 |
| | | | 18.8143 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103270 |
| | | | 19.0561 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103269 |
| | | | 19.3627 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103271 |
| | | | 20.5448 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103272 |
| | | | 5.3193 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX008140 |
| | | | 8.04115 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX037199 |
| | | WBls:0000063 (103) |
| | | WBls:0000064 (14) |
| | | WBls:0000065 (16) |
| | | WBls:0000068 | 2.7163 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265364 |
| | | | 3.08083 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265361 |
| | | | 3.16937 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265360 |
| | | | 3.36493 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265362 |
| | | | 3.4156 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265363 |
| | | | 3.591 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265365 |
| | | WBls:0000131 | 0.0243741 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0004015.SRP029448.SRX343228 |
| | | | 0.0618474 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0006876.SRP029448.SRX343222 |
| | | | 0.102435 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0004015.SRP029448.SRX343227 |
| | | | 0.164328 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0004015.SRP029448.SRX343220 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0004015.SRP029448.SRX343229 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0006771.SRP029448.SRX343225 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0006771.SRP029448.SRX343226 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0006876.SRP029448.SRX343221 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0006876.SRP029448.SRX343223 |
| | | WBls:0000141 | 0.0814034 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000141.Hermaphrodite.WBbt:0007833.SRP029448.SRX343161 |
| | | WBls:0000151 | 0.0435724 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0004804.SRP029448.SRX343230 |
| | | | 0.0862448 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0004804.SRP029448.SRX343232 |
| | | | 0.182452 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0007833.SRP029448.SRX343162 |
| | | | 0.566157 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0004015.SRP029448.SRX343280 |
| | | | 0.747005 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0004458.SRP029448.SRX343256 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0003810.SRP029448.SRX343308 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0004015.SRP029448.SRX343281 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0004015.SRP029448.SRX343282 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0004458.SRP029448.SRX343255 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0004458.SRP029448.SRX343257 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0004804.SRP029448.SRX343231 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0008115.SRP029448.SRX343326 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0008115.SRP029448.SRX343327 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0008115.SRP029448.SRX343328 |
| | | WBls:0000171 | 0.000208048 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000171.Hermaphrodite.WBbt:0003810.SRP029448.SRX343309 |
| | | | 0.0452658 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000171.Hermaphrodite.WBbt:0004804.SRP029448.SRX343233 |
| | | | 0.0742037 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000171.Hermaphrodite.WBbt:0004804.SRP029448.SRX343234 |
| | | | 0.130057 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000171.Hermaphrodite.WBbt:0004458.SRP029448.SRX343259 |
| | | | 1.66759e-14 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000171.Hermaphrodite.WBbt:0004804.SRP029448.SRX343235 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000171.Hermaphrodite.WBbt:0003810.SRP029448.SRX343310 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000171.Hermaphrodite.WBbt:0003810.SRP029448.SRX343311 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000171.Hermaphrodite.WBbt:0004015.SRP029448.SRX343283 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000171.Hermaphrodite.WBbt:0004015.SRP029448.SRX343284 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000171.Hermaphrodite.WBbt:0004015.SRP029448.SRX343285 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000171.Hermaphrodite.WBbt:0004458.SRP029448.SRX343260 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000171.Hermaphrodite.WBbt:0007833.SRP029448.SRX343163 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000171.Hermaphrodite.WBbt:0008115.SRP029448.SRX343330 |
| | | | 8.77152 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000171.Hermaphrodite.WBbt:0008115.SRP029448.SRX343329 |
| | | | 9.38461e-12 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000171.Hermaphrodite.WBbt:0004458.SRP029448.SRX343258 |
| | | WBls:0000181 | 0.244198 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000181.Hermaphrodite.WBbt:0007833.SRP029448.SRX343164 |
| | | WBls:0000191 | 0.11568 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000191.Hermaphrodite.WBbt:0007833.SRP029448.SRX343165 |
| | | WBls:0000201 | 1e-10 | From_analysis (12) |
| | | WBls:0000221 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0003810.SRP029448.SRX343314 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0003810.SRP029448.SRX343315 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004015.SRP029448.SRX343290 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004015.SRP029448.SRX343291 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004458.SRP029448.SRX343264 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004458.SRP029448.SRX343265 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004458.SRP029448.SRX343266 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004804.SRP029448.SRX343241 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0008115.SRP029448.SRX343333 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0008115.SRP029448.SRX343334 |
| | | WBls:0000231 | 0.161124 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000231.Hermaphrodite.WBbt:0007833.SRP029448.SRX343167 |
| | | WBls:0000251 | 0.100793 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0007833.SRP029448.SRX343168 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0003810.SRP029448.SRX343317 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0004458.SRP029448.SRX343268 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0004804.SRP029448.SRX343242 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0004804.SRP029448.SRX343243 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0004804.SRP029448.SRX343244 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0008115.SRP029448.SRX343335 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0008115.SRP029448.SRX343336 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0008115.SRP029448.SRX343337 |
| | | | 4.67348e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0004015.SRP029448.SRX343292 |
| | | WBls:0000261 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000261.Hermaphrodite.WBbt:0007833.SRP029448.SRX343169 |
| | | WBls:0000281 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000281.Hermaphrodite.WBbt:0007833.SRP029448.SRX343170 |
| | | WBls:0000291 | 1.08042 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0003810.SRP029448.SRX343318 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004015.SRP029448.SRX343296 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004458.SRP029448.SRX343271 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004458.SRP029448.SRX343272 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004804.SRP029448.SRX343245 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004804.SRP029448.SRX343246 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004804.SRP029448.SRX343247 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0008115.SRP029448.SRX343338 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0008115.SRP029448.SRX343339 |
| | | | 2.72633 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004015.SRP029448.SRX343294 |
| | | | 3.30804 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004015.SRP029448.SRX343295 |
| | | | 0 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0007833.SRP029448.SRX343171 |
| | | | 8.93459e-08 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0003810.SRP029448.SRX343319 |
| | | WBls:0000301 | 0.101536 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000301.Hermaphrodite.WBbt:0007833.SRP029448.SRX343172 |
| | | WBls:0000311 | 0.350292 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000311.Hermaphrodite.WBbt:0007833.SRP029448.SRX343173 |
| | | WBls:0000321 | 0.870008 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000321.Hermaphrodite.WBbt:0007833.SRP029448.SRX343174 |
| | | WBls:0000331 | 0.283384 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000331.Hermaphrodite.WBbt:0007833.SRP029448.SRX343175 |
| | | | 0.728585 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000331.Hermaphrodite.WBbt:0007833.SRP029448.SRX343176 |
| | | WBls:0000351 | 0.575478 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000351.Hermaphrodite.WBbt:0007833.SRP029448.SRX343179 |
| | | | 0.97766 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000351.Hermaphrodite.WBbt:0007833.SRP029448.SRX343178 |
| | | WBls:0000361 | 0.754634 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000361.Hermaphrodite.WBbt:0007833.SRP029448.SRX343180 |
| | | WBls:0000381 | 0.215487 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004804.SRP029448.SRX343248 |
| | | | 0.247776 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004015.SRP029448.SRX343297 |
| | | | 0.853103 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004015.SRP029448.SRX343299 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0003810.SRP029448.SRX343320 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004458.SRP029448.SRX343274 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004458.SRP029448.SRX343275 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004804.SRP029448.SRX343249 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004804.SRP029448.SRX343250 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0008115.SRP029448.SRX343340 |
| | | WBls:0000391 | 2.5882 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000391.Hermaphrodite.WBbt:0007833.SRP029448.SRX343181 |
| | | WBls:0000401 | 3.09519 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000401.Hermaphrodite.WBbt:0007833.SRP029448.SRX343182 |
| | | WBls:0000421 | 4.14759 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000421.Hermaphrodite.WBbt:0007833.SRP029448.SRX343184 |
| | | WBls:0000431 | 5.28358 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000431.Hermaphrodite.WBbt:0007833.SRP029448.SRX343185 |
| | | WBls:0000451 | 6.20419 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000451.Hermaphrodite.WBbt:0007833.SRP029448.SRX343186 |
| | | WBls:0000461 | 8.04505 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000461.Hermaphrodite.WBbt:0007833.SRP029448.SRX343187 |
| | | WBls:0000471 | 0.0365289 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0004015.SRP029448.SRX343301 |
| | | | 11.7144 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0007833.SRP029448.SRX343189 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0004458.SRP029448.SRX343276 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0004804.SRP029448.SRX343251 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0008115.SRP029448.SRX343341 |
| | | | 2.96466 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0004015.SRP029448.SRX343300 |
| | | | 3.46217 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0004015.SRP029448.SRX343302 |
| | | WBls:0000491 | 8.89626 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000491.Hermaphrodite.WBbt:0007833.SRP029448.SRX343191 |
| | | WBls:0000501 | 20.0513 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000501.Hermaphrodite.WBbt:0007833.SRP029448.SRX343192 |
| | | WBls:0000511 | 22.0475 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000511.Hermaphrodite.WBbt:0007833.SRP029448.SRX343194 |
| | | WBls:0000521 | 23.6318 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000521.Hermaphrodite.WBbt:0007833.SRP029448.SRX343195 |
| | | WBls:0000531 | 20.2697 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000531.Hermaphrodite.WBbt:0007833.SRP029448.SRX343196 |
| | | | 37.2273 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000531.Hermaphrodite.WBbt:0007833.SRP029448.SRX343197 |
| | | WBls:0000541 | 12.6512 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000541.Hermaphrodite.WBbt:0007833.SRP029448.SRX343199 |
| | | | 26.8007 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000541.Hermaphrodite.WBbt:0007833.SRP029448.SRX343198 |
| | | WBls:0000551 | 35.8778 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000551.Hermaphrodite.WBbt:0007833.SRP029448.SRX343200 |
| | | WBls:0000561 | 36.5237 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000561.Hermaphrodite.WBbt:0007833.SRP029448.SRX343201 |
| | | WBls:0000581 | 35.931 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000581.Hermaphrodite.WBbt:0007833.SRP029448.SRX343202 |
| | | WBls:0000621 | 33.9959 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000621.Hermaphrodite.WBbt:0007833.SRP029448.SRX343203 |
| | | WBls:0000674 | 4.34203 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265366 |
| | | | 4.64475 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265370 |
| | | | 5.06998 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265367 |
| | | | 5.27654 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265369 |
| | | | 5.37835 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265371 |
| | | | 5.65087 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265368 |
| | | WBls:0000676 | 14.9867 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000676.Hermaphrodite.WBbt:0007833.SRP021083.SRX265372 |
| | | | 16.4801 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000676.Hermaphrodite.WBbt:0007833.SRP021083.SRX265374 |
| | | | 16.5617 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000676.Hermaphrodite.WBbt:0007833.SRP021083.SRX265375 |
| | | | 16.5755 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000676.Hermaphrodite.WBbt:0007833.SRP021083.SRX265373 |
| | | WBls:0000694 | 26.7259 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000694.Hermaphrodite.WBbt:0007833.SRP029448.SRX343205 |
| | | WBls:0000695 | 21.6355 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000695.Hermaphrodite.WBbt:0007833.SRP029448.SRX343206 |
| | | WBls:0000696 | 16.7369 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000696.Hermaphrodite.WBbt:0007833.SRP029448.SRX343207 |
| | | WBls:0000697 | 16.8117 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000697.Hermaphrodite.WBbt:0007833.SRP029448.SRX343208 |
| | | WBls:0000699 | 7.33556 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000699.Hermaphrodite.WBbt:0007833.SRP029448.SRX343210 |
| | | WBls:0000700 | 4.4398 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000700.Hermaphrodite.WBbt:0007833.SRP029448.SRX343211 |
| | | WBls:0000701 | 6.20558 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000701.Hermaphrodite.WBbt:0007833.SRP029448.SRX343212 |
| | | WBls:0000702 | 3.14799 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000702.Hermaphrodite.WBbt:0007833.SRP029448.SRX343213 |
| | | WBls:0000703 | 3.44045 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000703.Hermaphrodite.WBbt:0007833.SRP029448.SRX343214 |
| | GO_annotation (21) |
| | Ortholog (46) |
| | Structured_description | Concise_description | unc-53 encodes at least five large (~1200-1600 residue) proteins, orthologous to human NAV1, NAV2/RAINB1 (OMIM:607026), and NAV3, and homologous to Drosophila CG10662; UNC-53 proteins are required for anteroposterior guidance of migrating cells, axons, and excretory cell canals; unc-53 mutations affect egg laying, backward locomotion, body size, and male mating; UNC-53 proteins vary in their N-terminal regions but share common C-terminal sequences with a AAA-ATPase domain; the UNC-53 N-terminus physically interacts with ABI-1, suggesting that UNC-53 may function as a scaffold to link the ARP2/3 complex to ABI-1; UNC-53 also interacts both physically and genetically with SEM-5; unc-53 is expressed in those cells requiring it, suggesting that its function is cell-autonomous; overexpression of unc-53 induces excess cellular outgrowth. | Paper_evidence (11) |
| | | | | Curator_confirmed | WBPerson1843 |
| | | | | | WBPerson567 |
| | | | | Date_last_updated | 13 Nov 2012 00:00:00 |
| | | Automated_description | Predicted to enable actin filament binding activity. Involved in several processes, including backward locomotion; positive regulation of locomotion; and reproductive behavior. Located in cytoplasm. Expressed in several structures, including excretory cell; hermaphrodite distal tip cell; neurons; non-striated muscle; and socket cell. Is an ortholog of human NAV1 (neuron navigator 1). | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Disease_info | Potential_model | DOID:2559 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:15998) |
| Molecular_info | Corresponding_CDS | F45E10.1a |
| | | F45E10.1b |
| | | F45E10.1c |
| | | F45E10.1d |
| | | F45E10.1e |
| | | F45E10.1f |
| | | F45E10.1g |
| | | F45E10.1h |
| | Corresponding_CDS_history | F45E10.1:wp82 |
| | Corresponding_transcript | F45E10.1a.1 |
| | | F45E10.1b.1 |
| | | F45E10.1c.1 |
| | | F45E10.1d.1 |
| | | F45E10.1e.1 |
| | | F45E10.1f.1 |
| | | F45E10.1g.1 |
| | | F45E10.1h.1 |
| | Other_sequence (27) |
| | Associated_feature (66) |
| Experimental_info | RNAi_result (14) |
| | Expr_pattern (12) |
| | Drives_construct (25) |
| | Construct_product | WBCnstr00009444 |
| | | WBCnstr00010519 |
| | | WBCnstr00010520 |
| | | WBCnstr00010521 |
| | | WBCnstr00034150 |
| | Antibody | WBAntibody00001615 |
| | | WBAntibody00001625 |
| | Microarray_results (40) |
| | Expression_cluster (219) |
| | Interaction (103) |
| | Anatomy_function | WBbtf0113 |
| | | WBbtf0114 |
| | | WBbtf0118 |
| | | WBbtf0119 |
| Map_info | Map | II | Position | 3.16568 | Error | 0.005694 |
| | Well_ordered |
| | Positive | Positive_clone | F45E10 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | | | T28D2 |
| | Mapping_data | 2_point | 43 |
| | | Multi_point (11) |
| | | Pos_neg_data | 2145 |
| | | | 2146 |
| | | | 2159 |
| | | | 2163 |
| | | | 4533 |
| | | | 4534 |
| | | | 4535 |
| | | | 4536 |
| | | | 4539 |
| | | | 10562 |
| Reference (99) |
| Method | Gene |
