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WormBase Tree Display for Gene: WBGene00006713

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Name Class

WBGene00006713SMapS_parentSequenceR01H2
IdentityVersion1
NameCGC_nameubc-18Person_evidenceWBPerson89
Sequence_nameR01H2.6
Molecular_nameR01H2.6
R01H2.6.1
CE25067
Other_nameCELE_R01H2.6Accession_evidenceNDBBX284603
Public_nameubc-18
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:41WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classubc
Allele (15)
StrainWBStrain00005857
WBStrain00040591
WBStrain00005852
WBStrain00005853
WBStrain00005855
WBStrain00005856
RNASeq_FPKM (74)
GO_annotation (28)
Contained_in_operonCEOP3408
Ortholog (39)
ParalogWBGene00002344Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00006708Caenorhabditis elegansFrom_analysisPanther
WBGene00006717Caenorhabditis elegansFrom_analysisPanther
WBGene00006719Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00006720Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionubc-18 encodes an E2 ubiquitin-conjugating enzyme related to human UBCH7 (OMIM:603731); UBC-18 activity is required for normal growth and reproduction, and UBC-18 functions redundantly with LIN-35/Rb and other class B synthetic multivulval (SynMuv) gene products to regulate pharyngeal morphogenesis during embryonic development; ubc-18 transcripts are detected in the germline, embryos, late larval stages, and adults, suggesting that UBC-18 may function maternally to regulate several aspects of C. elegans development; the substrates of UBC-18 are not yet known.Paper_evidenceWBPaper00005337
WBPaper00005931
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnables ubiquitin conjugating enzyme activity and ubiquitin protein ligase binding activity. Involved in determination of adult lifespan; embryonic digestive tract morphogenesis; and protein metabolic process. Acts upstream of or within animal organ morphogenesis. Predicted to be located in nucleus. Predicted to be part of ubiquitin ligase complex. Is an ortholog of human UBE2L3 (ubiquitin conjugating enzyme E2 L3) and UBE2L5 (ubiquitin conjugating enzyme E2 L5).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSR01H2.6
Corresponding_transcriptR01H2.6.1
Other_sequence (80)
Associated_featureWBsf651163
WBsf651164
WBsf1015192
WBsf226895
WBsf226896
Experimental_infoRNAi_result (20)
Expr_patternExpr9706
Expr1011748
Expr1032796
Expr1154820
Expr1200345
Expr2017704
Expr2035842
Drives_constructWBCnstr00034199
Construct_productWBCnstr00034199
Microarray_results (19)
Expression_cluster (133)
Interaction (63)
Map_infoMapIIIPosition-0.799521Error0.00164
PositivePositive_cloneR01H2Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4747
Pseudo_map_position
Reference (42)
RemarkSequence connection from [Jones D, Crowe E, Stevens TA, Candido EPM], 02/06/10 krb.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene