WormBase Tree Display for Gene: WBGene00006529
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| WBGene00006529 | SMap | S_parent | Sequence | C47B2 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | tba-2 | |||||||
| Sequence_name | C47B2.3 | ||||||||
| Molecular_name | C47B2.3 | ||||||||
| C47B2.3.1 | |||||||||
| CE17563 | |||||||||
| C47B2.3.2 | |||||||||
| Other_name | Alpha-tubulin | Accession_evidence | EMBL | D14965 | |||||
| TUBA4B | |||||||||
| mel-45 | Person_evidence | WBPerson399 | |||||||
| CELE_C47B2.3 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | tba-2 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | tba | ||||||||
| Allele (42) | |||||||||
| Legacy_information | [C.elegansII] NMK. Encodes alpha tubulin. tba-2:lacZ expressed in touch cells, motor neurons and certain other neurons. [SQ] | ||||||||
| [Mains PE] Dominant, temperature-sensitive maternal-effect lethal. Defective early cleavage divisions. Homozygous nonconditional maternal-effect lethal. | |||||||||
| Strain | WBStrain00008449 | ||||||||
| WBStrain00008455 | |||||||||
| WBStrain00008457 | |||||||||
| WBStrain00007877 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (24) | |||||||||
| Contained_in_operon | CEOP1680 | ||||||||
| Ortholog (50) | |||||||||
| Paralog (16) | |||||||||
| Structured_description | Concise_description | tba-2 encodes an alpha-tubulin. | Paper_evidence | WBPaper00004402 | |||||
| WBPaper00006395 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 08 Jan 2009 00:00:00 | ||||||||
| Automated_description | Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Involved in several processes, including centrosome localization; establishment of mitotic spindle orientation; and regulation of cytokinesis. Predicted to be located in cytoplasm and microtubule. Expressed in several structures, including body wall musculature; intestine; neurons; pharynx; and ventral nerve cord. Human ortholog(s) of this gene implicated in thrombocytopenia. Is an ortholog of human TUBA8 (tubulin alpha 8) and TUBAL3 (tubulin alpha like 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:1588 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12410) | ||||
| Molecular_info | Corresponding_CDS | C47B2.3 | |||||||
| Corresponding_CDS_history | C47B2.3b:wp123 | ||||||||
| Corresponding_transcript | C47B2.3.1 | ||||||||
| C47B2.3.2 | |||||||||
| Other_sequence (137) | |||||||||
| Associated_feature (11) | |||||||||
| Experimental_info | RNAi_result (52) | ||||||||
| Expr_pattern (11) | |||||||||
| Drives_construct | WBCnstr00009169 | ||||||||
| WBCnstr00012441 | |||||||||
| WBCnstr00039275 | |||||||||
| Construct_product | WBCnstr00004942 | ||||||||
| WBCnstr00015886 | |||||||||
| WBCnstr00038427 | |||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (205) | |||||||||
| Interaction (289) | |||||||||
| Map_info | Map | I | Position | 16.7819 | Error | 0.095464 | |||
| Positive | Positive_clone | C47B2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| NW#A4B | |||||||||
| Mapping_data | Multi_point | 5586 | |||||||
| 5686 | |||||||||
| Reference (57) | |||||||||
| Remark | Sequence connection updated on advice of JAH (was previously connected to F26E4.8) | ||||||||
| Sequence connection from [Gremke L, Culotti JG] | |||||||||
| Method | Gene |
