WormBase Tree Display for Gene: WBGene00006516
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| WBGene00006516 | SMap | S_parent | Sequence | C05D11 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | vps-16 | Person_evidence | WBPerson253 | |||||
| Sequence_name | C05D11.2 | ||||||||
| Molecular_name | C05D11.2 | ||||||||
| C05D11.2.1 | |||||||||
| CE24785 | |||||||||
| Other_name | tag-171 | Person_evidence | WBPerson201 | ||||||
| CELE_C05D11.2 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | vps-16 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 25 Apr 2005 13:36:33 | WBPerson2970 | Name_change | CGC_name | vps-16 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | vps | ||||||||
| Allele (32) | |||||||||
| Strain | WBStrain00035863 | ||||||||
| WBStrain00035869 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (19) | |||||||||
| Contained_in_operon | CEOP3376 | ||||||||
| Ortholog (34) | |||||||||
| Structured_description | Concise_description | vps-16 encodes the C. elegans homolog of the Saccharomyces cerevisiae vacuolar sorting protein Vps16p; in C. elegans, vps-16 activity is required for biogenesis of the lysosome-related gut granules and for embryonic development; in addition, vps-16 is required for normal body morphology and regulation of germline apoptosis. | Paper_evidence | WBPaper00005654 | |||||
| WBPaper00025054 | |||||||||
| WBPaper00025087 | |||||||||
| WBPaper00025094 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 23 Jan 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable actin binding activity. Involved in digestive tract development and embryo development. Predicted to be located in endosome. Predicted to be part of HOPS complex. Human ortholog(s) of this gene implicated in dystonia. Is an ortholog of human VPS16 (VPS16 core subunit of CORVET and HOPS complexes). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:543 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:14584) | ||||
| Molecular_info | Corresponding_CDS | C05D11.2 | |||||||
| Corresponding_transcript | C05D11.2.1 | ||||||||
| Other_sequence (15) | |||||||||
| Associated_feature | WBsf992763 | ||||||||
| WBsf225102 | |||||||||
| Experimental_info | RNAi_result (26) | ||||||||
| Expr_pattern | Chronogram238 | ||||||||
| Chronogram1216 | |||||||||
| Expr1013287 | |||||||||
| Expr1032671 | |||||||||
| Expr1143826 | |||||||||
| Expr2018011 | |||||||||
| Expr2036148 | |||||||||
| Drives_construct | WBCnstr00034330 | ||||||||
| Construct_product | WBCnstr00034330 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (97) | |||||||||
| Interaction (62) | |||||||||
| Map_info | Map | III | Position | -1.27394 | Error | 0.002006 | |||
| Positive | Positive_clone | C05D11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5643 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00025719 | ||||||||
| WBPaper00031212 | |||||||||
| WBPaper00031805 | |||||||||
| WBPaper00032272 | |||||||||
| WBPaper00036342 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
