WormBase Tree Display for Gene: WBGene00006410

WBGene00006410 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: ZK470
  Identity: Version: 2
    Name: CGC_name: nck-1 Person_evidence: WBPerson103
      Sequence_name: ZK470.5
      Molecular_name: ZK470.5a
        ZK470.5a.1
        CE31270
        ZK470.5b
        CE53627
        ZK470.5b.1
      Other_name: tag-22 Person_evidence: WBPerson201
        CELE_ZK470.5 Accession_evidence: NDB BX284606
      Public_name: nck-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:40 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 24 Aug 2005 11:18:38 WBPerson2970 Name_change: CGC_name: nck-1
                Other_name: tag-22
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: nck
    Allele (104)
    Strain: WBStrain00002409
      WBStrain00002332
      WBStrain00031573
      WBStrain00035589
    RNASeq_FPKM (74)
    GO_annotation: 00087952
      00087953
      00087954
      00087955
      00087956
      00087957
      00087958
      00087959
      00087960
    Ortholog (44)
    Paralog: WBGene00004774 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: nck-1 encodes an SH2/SH3 domain-containing protein orthologous to the human NCK adaptor proteins that link tyrosine kinase signaling to actin cytoskeleton reorganization; in C. elegans, nck-1 activity is required for excretory canal migration and full axon migration in mechanosensory neurons; a nck-1::gfp promoter fusion is expressed in the excretory cell and ventral cord motorneurons. Paper_evidence: WBPaper00032514
          Curator_confirmed: WBPerson48
            WBPerson1843
          Date_last_updated: 21 Aug 2009 00:00:00
      Automated_description: Predicted to enable receptor tyrosine kinase binding activity and signaling adaptor activity. Predicted to be involved in cell migration and signal transduction. Located in cytoplasm and nucleus. Expressed in several structures, including egg-laying apparatus; gonad; hypodermis; neuroblasts; and neurons. Is an ortholog of human NCK1 (NCK adaptor protein 1) and NCK2 (NCK adaptor protein 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: ZK470.5a
      ZK470.5b
    Corresponding_CDS_history: ZK470.5b:wp272
    Corresponding_transcript: ZK470.5a.1
      ZK470.5b.1
    Other_sequence (15)
    Associated_feature (19)
  Experimental_info: RNAi_result (12)
    Expr_pattern (18)
    Drives_construct: WBCnstr00002061
      WBCnstr00003001
      WBCnstr00004496
      WBCnstr00013363
      WBCnstr00013801
      WBCnstr00013802
      WBCnstr00013803
      WBCnstr00014491
      WBCnstr00034367
    Construct_product: WBCnstr00013802
      WBCnstr00013803
      WBCnstr00014490
      WBCnstr00014491
      WBCnstr00014494
      WBCnstr00021621
      WBCnstr00034367
    Antibody: WBAntibody00002579
      WBAntibody00003056
    Microarray_results (31)
    Expression_cluster (130)
    Interaction: WBInteraction000032625
      WBInteraction000032893
      WBInteraction000033397
      WBInteraction000033398
      WBInteraction000033790
      WBInteraction000033962
      WBInteraction000034071
      WBInteraction000034111
      WBInteraction000034367
      WBInteraction000043567
      WBInteraction000043568
      WBInteraction000043569
      WBInteraction000043570
      WBInteraction000047406
      WBInteraction000047483
      WBInteraction000049428
      WBInteraction000049770
      WBInteraction000120080
      WBInteraction000122869
      WBInteraction000123841
      WBInteraction000149440
      WBInteraction000156537
      WBInteraction000156538
      WBInteraction000156539
      WBInteraction000159756
      WBInteraction000159795
      WBInteraction000161837
      WBInteraction000161846
      WBInteraction000163038
      WBInteraction000163059
      WBInteraction000164233
      WBInteraction000164243
      WBInteraction000165101
      WBInteraction000167149
      WBInteraction000167338
      WBInteraction000167652
      WBInteraction000167739
      WBInteraction000169587
      WBInteraction000173996
      WBInteraction000174055
      WBInteraction000174110
      WBInteraction000174289
      WBInteraction000174474
      WBInteraction000183079
      WBInteraction000210239
      WBInteraction000213258
      WBInteraction000264918
      WBInteraction000278936
      WBInteraction000323014
      WBInteraction000339775
      WBInteraction000347801
      WBInteraction000357316
      WBInteraction000361788
      WBInteraction000373578
      WBInteraction000394611
      WBInteraction000418037
      WBInteraction000437397
      WBInteraction000501253
      WBInteraction000501254
      WBInteraction000501255
      WBInteraction000541272
      WBInteraction000541292
      WBInteraction000541293
      WBInteraction000541294
      WBInteraction000546213
      WBInteraction000546214
      WBInteraction000546215
      WBInteraction000546216
      WBInteraction000546217
      WBInteraction000546218
      WBInteraction000546219
      WBInteraction000546220
      WBInteraction000546221
      WBInteraction000546222
      WBInteraction000546223
      WBInteraction000546224
      WBInteraction000546225
      WBInteraction000546226
      WBInteraction000546227
      WBInteraction000546228
      WBInteraction000546229
      WBInteraction000546230
      WBInteraction000546231
      WBInteraction000546232
      WBInteraction000546233
      WBInteraction000546234
      WBInteraction000546235
      WBInteraction000546236
      WBInteraction000546237
      WBInteraction000546238
      WBInteraction000546239
      WBInteraction000546240
      WBInteraction000546241
      WBInteraction000546242
      WBInteraction000546243
      WBInteraction000546244
      WBInteraction000546245
      WBInteraction000552114
      WBInteraction000563425
      WBInteraction000568599
      WBInteraction000568600
      WBInteraction000568601
      WBInteraction000568602
      WBInteraction000579114
      WBInteraction000579115
      WBInteraction000579116
      WBInteraction000579117
  Map_info: Map: X Position: -8.1368 Error: 0.089595
    Positive: Positive_clone: ZK470 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4949
        5017
    Pseudo_map_position
  Reference (21)
  Remark: Gene name created from parsing 'genotype' field from CGC strain information CGC_data_submission
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene