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WormBase Tree Display for Gene: WBGene00006385

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Name Class

WBGene00006385SMapS_parentSequenceR119
IdentityVersion1
NameCGC_nametaf-4
Sequence_nameR119.6
Molecular_nameR119.6
R119.6.1
CE39613
Other_nameCELE_R119.6Accession_evidenceNDBBX284601
Public_nametaf-4
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:40WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classtaf
AlleleWBVar00606608
WBVar00606609
WBVar00606610
WBVar00606611
WBVar00606612
WBVar00606613
WBVar00606614
WBVar01529629
WBVar00606615
WBVar00606616
WBVar01529630
WBVar00606617
WBVar00606618
WBVar00606619
WBVar01267250
WBVar00606620
WBVar00606621
WBVar00606622
WBVar01992710
WBVar00606623
WBVar01992711
WBVar00606624
WBVar00606625
WBVar00266746
WBVar00606626
WBVar00606627
WBVar00606628
WBVar00606629
WBVar00606630
WBVar00606631
WBVar00606632
WBVar00606633
WBVar00606634
WBVar00606635
WBVar00606636
WBVar00606637
WBVar00606638
WBVar01265028
WBVar00606639
WBVar01402426
WBVar01270583
WBVar01835298
WBVar00232878
WBVar00003091
WBVar00003096
WBVar00003101
WBVar01711312
WBVar00254913
WBVar01711313
WBVar00324017
WBVar01711314
WBVar00092614
WBVar00324018
WBVar01271694
WBVar00324019
WBVar00324020
WBVar01782656
WBVar00324021
WBVar01474548
WBVar01474549
WBVar00324022
WBVar01474550
WBVar00324023
WBVar00324024
WBVar01272805
WBVar01988300
WBVar02005846
WBVar02005847
WBVar02005848
WBVar01269472
WBVar02005849
WBVar01403366
WBVar01403378
WBVar01898004
WBVar01499786
WBVar02028067
WBVar01403389
WBVar01497400
WBVar01403400
WBVar01403411
WBVar01639968
WBVar02088496
WBVar01639969
WBVar02151158
WBVar01639970
WBVar01499619
WBVar01639971
WBVar01639972
WBVar01680536
WBVar01680537
WBVar01955587
WBVar01268361
WBVar01929917
WBVar01929918
WBVar01929919
WBVar00095211
WBVar00095212
WBVar01929920
WBVar00095213
WBVar01929921
WBVar01761527
WBVar01761528
WBVar00235212
WBVar00147317
WBVar00147318
WBVar00147319
WBVar00147320
WBVar00147321
WBVar02125922
WBVar00147322
WBVar01622487
WBVar00147324
WBVar01266139
WBVar00147325
WBVar00147327
WBVar00147329
WBVar00147330
WBVar00606604
WBVar00147331
WBVar00606605
WBVar00147332
WBVar00606606
WBVar00147333
WBVar00606607
StrainWBStrain00036170
RNASeq_FPKM (74)
GO_annotation (22)
Ortholog (40)
Structured_descriptionConcise_descriptiontaf-4 encodes a TAFII (TBP(TATA-binding protein)-associated factor) that is orthologous to human TAF4 (hTAFII130); TAF-4 is predicted to be a component of the TFIID mRNA transcription complex and is generally required for early embryonic mRNA transcription; consistent with this observation, taf-4(RNAi) results in embryonic lethality at the ~100-cell stage with little cell differentiation, similar to the loss of AMA-1/RNA polymerase II activity; TAF-4 is detected in nuclei in the adult germline, oocytes, and embryo, from the 2-cell stage through early morphogenesis.Paper_evidenceWBPaper00004890
Curator_confirmedWBPerson1843
Date_last_updated26 Jan 2005 00:00:00
Automated_descriptionPredicted to enable DNA binding activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Involved in several processes, including determination of adult lifespan; regulation of mitotic cell cycle, embryonic; and transcription initiation at RNA polymerase II promoter. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in spermatogenic failure 13. Is an ortholog of human TAF4B (TATA-box binding protein associated factor 4b).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0070182Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11538)
Molecular_infoCorresponding_CDSR119.6
Corresponding_CDS_historyR119.6:wp153
Corresponding_transcriptR119.6.1
Other_sequence (39)
Associated_featureWBsf643011
WBsf980924
WBsf982485
WBsf1009079
WBsf217127
WBsf217128
Transcription_factorWBTranscriptionFactor000206
WBTranscriptionFactor000442
Experimental_infoRNAi_result (40)
Expr_patternExpr1027683
Expr1032582
Expr1155419
Expr2017214
Expr2035350
Construct_productWBCnstr00005322
WBCnstr00005323
AntibodyWBAntibody00000409
Microarray_results (21)
Expression_cluster (84)
Interaction (90)
Map_info (3)
Reference (17)
RemarkSequence connection from [source: A Walker]
This gene was previously called taf-5. [krb 020614]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene