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WormBase Tree Display for Gene: WBGene00006333

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Name Class

WBGene00006333SMapS_parentSequenceC48C5
IdentityVersion1
NameCGC_namesup-28Person_evidenceWBPerson261
Sequence_nameC48C5.t6
Molecular_nameC48C5.t6
Other_namertw-8
CELE_C48C5.T6Accession_evidenceNDBBX284606
Public_namesup-28
DB_infoDatabaseNDBlocus_tagCELE_C48C5.T6
NCBIgene192050
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:40WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001272
Gene_classsup
Reference_alleleWBVar00144527
Allele (13)
Legacy_informatione2058 (pka sup-21) : amber suppressor suppresses tra-3(e1107) dpy-20(e2017) but not unc-13(e450); no gross phenotype alone; probably alteration in tRNATrp gene. ES3 in presence of tra-3(e1107) ME3. NA1.
See also e2226
StrainWBStrain00004514
RNASeq_FPKM (74)
Structured_descriptionConcise_descriptionsup-28 encodes a tRNA-Trp that was initially identified in screens for suppressors of amber mutations in the sex determination gene tra-3; sup-28 mutations behave as informational suppressors, inserting tryptophan at premature stop codons; however, as sup-28 mutations do not suppress all known amber mutations, sup-28 may be expressed in a tissue-specific manner; sup-28 is an X-linked gene, but does not appear to be dosage compensated, as it is expressed at lower levels in XO males when compared to XX hermaphrodites.Paper_evidenceWBPaper00001009
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionExpressed in body wall musculature; hermaphrodite gonad; hypodermis; intestine; and vulva.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_transcriptC48C5.t6
Experimental_infoExpr_patternExpr13224
Expression_clusterWBPaper00065975:P-body_vs_oocyte_depleted
WBPaper00065975:P-body_vs_WholeAnimal_depleted
InteractionWBInteraction000000021
WBInteraction000000022
WBInteraction000002805
WBInteraction000030353
WBInteraction000031804
WBInteraction000031805
Map_infoMapXPosition0.451293Error0.00257
Well_ordered
PositivePositive_cloneD1073
TP3
Mapping_data2_point3179
Multi_point3209
3212
3288
4714
5638
Reference (14)
RemarkBlastN of the embl sequence to genomic gives 100% matches including the flanking sequences to D1073.t1, disitnguishing it from nearby sup-33.[sdm 0005]
sequence connection to D1073.t1 was incorrect. C48C5.t6(aka D1073.t2)Person_evidenceWBPerson261
MethodGene