WormBase Tree Display for Gene: WBGene00005018
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| WBGene00005018 | SMap | S_parent | Sequence | F23H12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | sqt-3 | Person_evidence | WBPerson153 | |||||
| Sequence_name | F23H12.4 | ||||||||
| Molecular_name | F23H12.4a | ||||||||
| F23H12.4a.1 | |||||||||
| CE05707 | |||||||||
| F23H12.4b | |||||||||
| CE46560 | |||||||||
| F23H12.4b.1 | |||||||||
| Other_name | col-1 | ||||||||
| dpy-15 | |||||||||
| rol-4 | Paper_evidence | WBPaper00024637 | |||||||
| Person_evidence | WBPerson261 | ||||||||
| Rol | |||||||||
| CELE_F23H12.4 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | sqt-3 | ||||||||
| DB_info | Database | AceView | gene | 5M833 | |||||
| WormQTL | gene | WBGene00005018 | |||||||
| WormFlux | gene | WBGene00005018 | |||||||
| NDB | locus_tag | CELE_F23H12.4 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00005018|UniProtKB=P08124 | |||||||
| family | PTHR24637 | ||||||||
| NCBI | gene | 179693 | |||||||
| RefSeq | protein | NM_001269484.3 | |||||||
| NM_001269483.3 | |||||||||
| SwissProt | UniProtAcc | P08124 | |||||||
| TrEMBL | UniProtAcc | H2L2C4 | |||||||
| UniProt_GCRP | UniProtAcc | P08124 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:37 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 23 Aug 2005 10:47:27 | WBPerson2970 | Event | Acquires_merge | WBGene00004396 | ||||
| Name_change | Other_name | rol-4 | |||||||
| Acquires_merge | WBGene00004396 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sqt | ||||||||
| Reference_allele | WBVar00242688 | ||||||||
| Allele (64) | |||||||||
| Possibly_affected_by | WBVar02157913 | ||||||||
| WBVar02157914 | |||||||||
| WBVar02157915 | |||||||||
| WBVar02157916 | |||||||||
| WBVar02157917 | |||||||||
| Legacy_information | sc63ts : homozygotes at 25x are non-roller dumpy heterozygotes sc63/+ are non-dumpy left-handed roller in adult high penetrance deformed tail at 25x. ES3 ME0 (25x). At 15x slightly dumpy. NA > 8 (sc80ts (resembles sc63) e24sd ts (pka dpy-15 : dumpy inviable at 25x e24/+ dumpy at 25x) etc.). | ||||||||
| See sqt-3. | |||||||||
| See also e24, e2117 | |||||||||
| [C.elegansII] sc63ts,sd : homozygotes at 25C are non-roller dumpy, heterozygotes sc63/+ are non-dumpy left-handed roller in adult; high penetrance deformed tail at 25C. ES3 ME0 (25C). At 15C slightly dumpy. OA3: sc80ts (resembles sc63), e24sd,ts (pka dpy-15, dumpy inviable at 25C, e24/+ dumpy at 25C, sometimes Lon at15C), sc42 (recessive left roller), e2117ts (extreme dumpy early larval lethal at 25C). Cloned: encodes 295 aa collagen (pka col-1), dpy-13 family; mutations all missense; expressed at each larval stage, 4 - 2.5 hours before lethargus. [Kramer et al. 1982; Keyl et al. 1994; IA] | |||||||||
| sc8 : adults and L4 larvae left-handed rollers. ES3 (adult) ME2. NA3 (b238ts : at 25x rolls only in adult at 16x wildtype). | |||||||||
| [C.elegansII] sc8 : adults and L4 larvae left-handed rollers. ES3 (adult) ME2. OA2: b238ts (at 25C rolls only in adult, WT at 16C). [Cox et al. 1980] | |||||||||
| Strain (23) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00023410 | ||||||||
| 00023411 | |||||||||
| 00023412 | |||||||||
| 00023413 | |||||||||
| 00038921 | |||||||||
| 00038922 | |||||||||
| 00038923 | |||||||||
| 00038924 | |||||||||
| 00038925 | |||||||||
| 00113426 | |||||||||
| Ortholog (27) | |||||||||
| Paralog (163) | |||||||||
| Structured_description | Concise_description | sqt-3 encodes a cuticle collagen; during development, sqt-3 activity is essential for viability and normal body morphology; genetic and expression studies indicate that SQT-3 is a cuticle component at all stages of development and that SQT-3 likely forms higher order cuticular structures with the DPY-17 cuticular collagen, both of which are candidate substrates for the DPY-31 procollagen C-proteinase. | Paper_evidence | WBPaper00000906 | |||||
| WBPaper00000927 | |||||||||
| WBPaper00002030 | |||||||||
| WBPaper00024637 | |||||||||
| WBPaper00027067 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 27 Mar 2007 00:00:00 | ||||||||
| Automated_description | Predicted to be a structural constituent of cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Located in collagen and cuticulin-based cuticle extracellular matrix. Expressed in hypodermis. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F23H12.4a | |||||||
| F23H12.4b | |||||||||
| Corresponding_transcript | F23H12.4a.1 | ||||||||
| F23H12.4b.1 | |||||||||
| Other_sequence (112) | |||||||||
| Associated_feature (12) | |||||||||
| Experimental_info | RNAi_result (17) | ||||||||
| Expr_pattern | Expr609 | ||||||||
| Expr617 | |||||||||
| Expr751 | |||||||||
| Expr4986 | |||||||||
| Expr1012789 | |||||||||
| Expr1032501 | |||||||||
| Expr1149371 | |||||||||
| Expr2016118 | |||||||||
| Expr2034353 | |||||||||
| Drives_construct | WBCnstr00035264 | ||||||||
| Construct_product | WBCnstr00035264 | ||||||||
| Antibody | WBAntibody00001056 | ||||||||
| Microarray_results (24) | |||||||||
| Expression_cluster (372) | |||||||||
| Interaction (234) | |||||||||
| WBProcess | WBbiopr:00000124 | ||||||||
| Map_info | Map | V | Position | 4.00808 | Error | 0.002342 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | F23H12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| ZC348 | |||||||||
| Mapping_data | 2_point (13) | ||||||||
| Multi_point (71) | |||||||||
| Pos_neg_data | 1745 | ||||||||
| 1750 | |||||||||
| 1755 | |||||||||
| 4300 | |||||||||
| 6870 | |||||||||
| 7396 | |||||||||
| 1758 | |||||||||
| Landmark_gene | |||||||||
| Reference (159) | |||||||||
| Method | Gene |
