WormBase Tree Display for Gene: WBGene00005018
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WBGene00005018 | SMap | S_parent | Sequence | F23H12 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | sqt-3 | Person_evidence | WBPerson153 | |||||
Sequence_name | F23H12.4 | ||||||||
Molecular_name | F23H12.4a | ||||||||
F23H12.4a.1 | |||||||||
CE05707 | |||||||||
F23H12.4b | |||||||||
CE46560 | |||||||||
F23H12.4b.1 | |||||||||
Other_name | col-1 | ||||||||
dpy-15 | |||||||||
rol-4 | Paper_evidence | WBPaper00024637 | |||||||
Person_evidence | WBPerson261 | ||||||||
Rol | |||||||||
CELE_F23H12.4 | Accession_evidence | NDB | BX284605 | ||||||
Public_name | sqt-3 | ||||||||
DB_info | Database | AceView | gene | 5M833 | |||||
WormQTL | gene | WBGene00005018 | |||||||
WormFlux | gene | WBGene00005018 | |||||||
NDB | locus_tag | CELE_F23H12.4 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00005018|UniProtKB=P08124 | |||||||
family | PTHR24637 | ||||||||
NCBI | gene | 179693 | |||||||
RefSeq | protein | NM_001269484.3 | |||||||
NM_001269483.3 | |||||||||
SwissProt | UniProtAcc | P08124 | |||||||
TrEMBL | UniProtAcc | H2L2C4 | |||||||
UniProt_GCRP | UniProtAcc | P08124 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:37 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 23 Aug 2005 10:47:27 | WBPerson2970 | Event | Acquires_merge | WBGene00004396 | ||||
Name_change | Other_name | rol-4 | |||||||
Acquires_merge | WBGene00004396 | ||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | sqt | ||||||||
Reference_allele | WBVar00242688 | ||||||||
Allele (64) | |||||||||
Possibly_affected_by | WBVar02157913 | ||||||||
WBVar02157914 | |||||||||
WBVar02157915 | |||||||||
WBVar02157916 | |||||||||
WBVar02157917 | |||||||||
Legacy_information | sc63ts : homozygotes at 25x are non-roller dumpy heterozygotes sc63/+ are non-dumpy left-handed roller in adult high penetrance deformed tail at 25x. ES3 ME0 (25x). At 15x slightly dumpy. NA > 8 (sc80ts (resembles sc63) e24sd ts (pka dpy-15 : dumpy inviable at 25x e24/+ dumpy at 25x) etc.). | ||||||||
See sqt-3. | |||||||||
See also e24, e2117 | |||||||||
[C.elegansII] sc63ts,sd : homozygotes at 25C are non-roller dumpy, heterozygotes sc63/+ are non-dumpy left-handed roller in adult; high penetrance deformed tail at 25C. ES3 ME0 (25C). At 15C slightly dumpy. OA3: sc80ts (resembles sc63), e24sd,ts (pka dpy-15, dumpy inviable at 25C, e24/+ dumpy at 25C, sometimes Lon at15C), sc42 (recessive left roller), e2117ts (extreme dumpy early larval lethal at 25C). Cloned: encodes 295 aa collagen (pka col-1), dpy-13 family; mutations all missense; expressed at each larval stage, 4 - 2.5 hours before lethargus. [Kramer et al. 1982; Keyl et al. 1994; IA] | |||||||||
sc8 : adults and L4 larvae left-handed rollers. ES3 (adult) ME2. NA3 (b238ts : at 25x rolls only in adult at 16x wildtype). | |||||||||
[C.elegansII] sc8 : adults and L4 larvae left-handed rollers. ES3 (adult) ME2. OA2: b238ts (at 25C rolls only in adult, WT at 16C). [Cox et al. 1980] | |||||||||
Strain (23) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00023410 | ||||||||
00023411 | |||||||||
00023412 | |||||||||
00023413 | |||||||||
00038921 | |||||||||
00038922 | |||||||||
00038923 | |||||||||
00038924 | |||||||||
00038925 | |||||||||
00113426 | |||||||||
Ortholog (27) | |||||||||
Paralog (163) | |||||||||
Structured_description | Concise_description | sqt-3 encodes a cuticle collagen; during development, sqt-3 activity is essential for viability and normal body morphology; genetic and expression studies indicate that SQT-3 is a cuticle component at all stages of development and that SQT-3 likely forms higher order cuticular structures with the DPY-17 cuticular collagen, both of which are candidate substrates for the DPY-31 procollagen C-proteinase. | Paper_evidence | WBPaper00000906 | |||||
WBPaper00000927 | |||||||||
WBPaper00002030 | |||||||||
WBPaper00024637 | |||||||||
WBPaper00027067 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 27 Mar 2007 00:00:00 | ||||||||
Automated_description | Predicted to be a structural constituent of cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Located in collagen and cuticulin-based cuticle extracellular matrix. Expressed in hypodermis. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | F23H12.4a | |||||||
F23H12.4b | |||||||||
Corresponding_transcript | F23H12.4a.1 | ||||||||
F23H12.4b.1 | |||||||||
Other_sequence (112) | |||||||||
Associated_feature | WBsf647363 | ||||||||
WBsf647364 | |||||||||
WBsf661887 | |||||||||
WBsf661888 | |||||||||
WBsf661889 | |||||||||
WBsf661890 | |||||||||
WBsf661891 | |||||||||
WBsf661892 | |||||||||
WBsf1001568 | |||||||||
WBsf1020563 | |||||||||
WBsf232637 | |||||||||
WBsf232638 | |||||||||
Experimental_info | RNAi_result (17) | ||||||||
Expr_pattern | Expr609 | ||||||||
Expr617 | |||||||||
Expr751 | |||||||||
Expr4986 | |||||||||
Expr1012789 | |||||||||
Expr1032501 | |||||||||
Expr1149371 | |||||||||
Expr2016118 | |||||||||
Expr2034353 | |||||||||
Drives_construct | WBCnstr00035264 | ||||||||
Construct_product | WBCnstr00035264 | ||||||||
Antibody | WBAntibody00001056 | ||||||||
Microarray_results (24) | |||||||||
Expression_cluster (372) | |||||||||
Interaction (234) | |||||||||
WBProcess | WBbiopr:00000124 | ||||||||
Map_info | Map | V | Position | 4.00808 | Error | 0.002342 | |||
Well_ordered | |||||||||
Positive | Positive_clone | F23H12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
ZC348 | |||||||||
Mapping_data | 2_point (13) | ||||||||
Multi_point (71) | |||||||||
Pos_neg_data | 1745 | ||||||||
1750 | |||||||||
1755 | |||||||||
4300 | |||||||||
6870 | |||||||||
7396 | |||||||||
1758 | |||||||||
Landmark_gene | |||||||||
Reference (159) | |||||||||
Method | Gene |