WormBase Tree Display for Gene: WBGene00004980
expand all nodes | collapse all nodes | view schema
WBGene00004980 | SMap | S_parent | Sequence | B0464 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | spk-1 | Person_evidence | WBPerson1315 | |||||
Sequence_name | B0464.5 | ||||||||
Molecular_name (13) | |||||||||
Other_name | srk-1 | ||||||||
rsk-1 | Paper_evidence | WBPaper00003988 | |||||||
CELE_B0464.5 | Accession_evidence | NDB | BX284603 | ||||||
Public_name | spk-1 | ||||||||
DB_info | Database (14) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:37 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | spk | ||||||||
Allele (80) | |||||||||
Strain | WBStrain00035941 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (25) | |||||||||
Ortholog (51) | |||||||||
Paralog (21) | |||||||||
Structured_description | Concise_description | spk-1 encodes a serine/threonine kinase orthologous to the highly conserved serine/arginine-rich protein kinases (SRPKs) that phosphorylate SR proteins, essential components of the pre-mRNA splicing machinery; SPK-1, required for embryogenesis and germline development, can directly bind and phosphorylate RSP-3 (CeSF2/ASF), an SR splicing factor homolog; SPK-1 is expressed predominantly in the adult germline; SPK-1 is homologous to human RSK2, which when mutated leads to Coffin-Lowry syndrome (OMIM:303600). | Paper_evidence (2) | ||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Enables protein serine/threonine kinase activity. Involved in embryo development. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including gonad and tail. Is an ortholog of human SRPK1 (SRSF protein kinase 1); SRPK2 (SRSF protein kinase 2); and SRPK3 (SRSF protein kinase 3). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | B0464.5a | |||||||
B0464.5b | |||||||||
B0464.5c | |||||||||
B0464.5d | |||||||||
Corresponding_CDS_history | B0464.5a:wp123 | ||||||||
B0464.5c:wp119 | |||||||||
Corresponding_transcript | B0464.5a.1 | ||||||||
B0464.5a.2 | |||||||||
B0464.5b.1 | |||||||||
B0464.5c.1 | |||||||||
B0464.5d.1 | |||||||||
Other_sequence (83) | |||||||||
Associated_feature (20) | |||||||||
Experimental_info | RNAi_result (17) | ||||||||
Expr_pattern | Chronogram621 | ||||||||
Expr439 | |||||||||
Expr1128 | |||||||||
Expr5076 | |||||||||
Expr1028333 | |||||||||
Expr1032478 | |||||||||
Expr1143250 | |||||||||
Expr2016060 | |||||||||
Expr2034296 | |||||||||
Drives_construct | WBCnstr00004059 | ||||||||
WBCnstr00035294 | |||||||||
Construct_product | WBCnstr00035294 | ||||||||
Microarray_results (50) | |||||||||
Expression_cluster (119) | |||||||||
Interaction (131) | |||||||||
WBProcess | WBbiopr:00000014 | ||||||||
Map_info | Map | III | Position | 0.536942 | Error | 0.008194 | |||
Positive | Positive_clone | B0464 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
T01H8 | |||||||||
Mapping_data | Multi_point | 5000 | |||||||
Pseudo_map_position | |||||||||
Reference (19) | |||||||||
Remark (2) | |||||||||
Method | Gene |