WormBase Tree Display for Gene: WBGene00004976
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| WBGene00004976 | SMap | S_parent | Sequence | K01A11 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | spe-41 | Person_evidence | WBPerson252 | |||||
| Sequence_name | K01A11.4 | ||||||||
| Molecular_name | K01A11.4a | ||||||||
| K01A11.4a.1 | |||||||||
| CE03452 | |||||||||
| K01A11.4b | |||||||||
| CE46278 | |||||||||
| K01A11.4b.1 | |||||||||
| Other_name | strpc3 | Accession_evidence | EMBL | AJ276029 | |||||
| trp-3 | CGC_data_submission | ||||||||
| CELE_K01A11.4 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | spe-41 | ||||||||
| DB_info | Database | AceView | gene | 3E530 | |||||
| WormQTL | gene | WBGene00004976 | |||||||
| WormFlux | gene | WBGene00004976 | |||||||
| NDB | locus_tag | CELE_K01A11.4 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004976|UniProtKB=G5EF09 | |||||||
| family | PTHR10117 | ||||||||
| NCBI | gene | 175446 | |||||||
| RefSeq | protein | NM_001393307.1 | |||||||
| NM_001267943.4 | |||||||||
| TREEFAM | TREEFAM_ID | TF320153 | |||||||
| TrEMBL | UniProtAcc | G3MTY7 | |||||||
| G5EF09 | |||||||||
| UniProt_GCRP | UniProtAcc | G5EF09 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:37 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | spe | ||||||||
| Allele (124) | |||||||||
| Strain | WBStrain00030942 | ||||||||
| WBStrain00036378 | |||||||||
| WBStrain00044684 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (20) | |||||||||
| Ortholog (36) | |||||||||
| Paralog | WBGene00006614 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00006615 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | spe-41 encodes one of three C. elegans calcium-permeable cation channels that are members of the TRPC (transient receptor potential canonical) subfamily of TRP channels; spe-41 activity is required in sperm for productive sperm-oocyte interactions during fertilization, after the point of gamete contact; SPE-41 is expressed solely in sperm and upon sperm activation, translocalizes from the membranous organelles of spermatids to the plasma membranes of the cell body and pseudopod of mature sperm, consistent with the observation that the activity of store-operated calcium channels in C. elegans is much higher in mature sperm than in spermatids; when expressed in mammalian tissue culture cells, SPE-41 activity is sufficient to enhance calcium influx; SPE-41 is also required for the generation of a rapid local calcium rise in the oocyte upon fertilization. | Paper_evidence | WBPaper00006041 | |||||
| WBPaper00049488 | |||||||||
| Person_evidence | WBPerson5535 | ||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Oct 2016 00:00:00 | ||||||||
| Automated_description | Enables store-operated calcium channel activity. Involved in calcium ion transport; intracellular calcium ion homeostasis; and single fertilization. Located in cytoplasmic vesicle and pseudopodium membrane. Expressed in sperm and spermatid. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | K01A11.4a | |||||||
| K01A11.4b | |||||||||
| Corresponding_transcript | K01A11.4a.1 | ||||||||
| K01A11.4b.1 | |||||||||
| Other_sequence | AJ276029 | ||||||||
| AY342006 | |||||||||
| Dviv_isotig19920 | |||||||||
| Associated_feature (11) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00001767 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00033799 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00016362 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00006311 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00049581 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr2639 | ||||||||
| Expr9972 | |||||||||
| Expr12933 | |||||||||
| Expr1014668 | |||||||||
| Expr1153307 | |||||||||
| Expr2016040 | |||||||||
| Expr2034275 | |||||||||
| Drives_construct | WBCnstr00022856 | ||||||||
| WBCnstr00022865 | |||||||||
| Construct_product | WBCnstr00022864 | ||||||||
| WBCnstr00022865 | |||||||||
| WBCnstr00022866 | |||||||||
| WBCnstr00023017 | |||||||||
| Antibody | WBAntibody00000663 | ||||||||
| WBAntibody00000880 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (183) | |||||||||
| Interaction (20) | |||||||||
| WBProcess | WBbiopr:00000067 | ||||||||
| Map_info | Map | III | Position | -6.94653 | Error | 0.048033 | |||
| Positive | Positive_clone | K01A11 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4362 | |||||||
| 4491 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (23) | |||||||||
| Remark | Gene name created from parsing 'genotype' field from CGC strain information [krb 020721] | ||||||||
| Sequence connection from [Smith H, Ward S], [krb 020722] | |||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
