WormBase Tree Display for Gene: WBGene00004962
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| WBGene00004962 | SMap | S_parent | Sequence | F53G12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | spe-8 | Person_evidence | WBPerson252 | |||||
| Sequence_name | F53G12.6 | ||||||||
| Molecular_name | F53G12.6 | ||||||||
| F53G12.6.1 | |||||||||
| CE29331 | |||||||||
| Other_name | CELE_F53G12.6 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | spe-8 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:37 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | spe | ||||||||
| Reference_allele | WBVar00087754 | ||||||||
| Allele (58) | |||||||||
| Legacy_information | hc40 : hermaphrodites and males produce nonfunctional nonmotile sperm with uniformly aberrant pseudopods. Self-fertility < 1% (16x or 25x). ES2 (adult). NA6 (hc50 hc53 etc.). | ||||||||
| [C.elegansII] hc40 : hermaphrodites produce nonfunctional nonmotile sperm with uniformly aberrant pseudopods; male sperm normal. Self-fertility < 1% (16C or 25C). ES2 (adult). OA5: hc50. hc53 etc. [L'Hernault et al. 1988; Shakes and Ward 1989a; BA] | |||||||||
| Strain | WBStrain00000280 | ||||||||
| WBStrain00000388 | |||||||||
| WBStrain00000389 | |||||||||
| WBStrain00000390 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (27) | |||||||||
| Ortholog (30) | |||||||||
| Paralog (60) | |||||||||
| Structured_description | Concise_description | spe-8 is predicted to encode a non-receptor tyrosine kinase with a SH2 domain; spe-8 is required for hermaphrodite spermatogenesis or sperm activation but not for male-derived sperm activation (sperm activation is the morphogenesis of a round non-motile spermatid to an amoeboid crawling sperm); however, mutant hermaphrodite spe-8 spermatids can transactivate and form functional sperm during mating with males; genetic and phenotypic evidence suggests that spe-8 acts in a common pathway with spe-12, spe-19, spe-27 and spe-29. | Paper_evidence | WBPaper00001166 | |||||
| WBPaper00001174 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 26 Jul 2010 00:00:00 | ||||||||
| Automated_description | Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Involved in spermatid development. Located in plasma membrane. Expressed in sperm and spermatocyte. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F53G12.6 | |||||||
| Corresponding_transcript | F53G12.6.1 | ||||||||
| Other_sequence | AW562244.1 | ||||||||
| OVC03170_1 | |||||||||
| JI465799.1 | |||||||||
| Acan_isotig15604 | |||||||||
| Associated_feature | WBsf982404 | ||||||||
| WBsf982405 | |||||||||
| WBsf982406 | |||||||||
| WBsf982407 | |||||||||
| WBsf1009031 | |||||||||
| WBsf1009032 | |||||||||
| WBsf217100 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00092942 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00070649 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00048171 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00070648 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00003757 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr11879 | ||||||||
| Expr11880 | |||||||||
| Expr1026654 | |||||||||
| Expr1151986 | |||||||||
| Expr2016050 | |||||||||
| Expr2034285 | |||||||||
| Drives_construct | WBCnstr00019504 | ||||||||
| WBCnstr00035304 | |||||||||
| Construct_product | WBCnstr00019504 | ||||||||
| WBCnstr00035304 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (117) | |||||||||
| Interaction (38) | |||||||||
| WBProcess | WBbiopr:00000069 | ||||||||
| Map_info | Map | I | Position | -19.2006 | Error | 0.152057 | |||
| Positive | Positive_clone | F53G12 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | 2_point | 3196 | |||||||
| Multi_point | 1045 | ||||||||
| 2661 | |||||||||
| 5490 | |||||||||
| Pos_neg_data | 6286 | ||||||||
| Reference (84) | |||||||||
| Remark | sequence is F53G12.6 [eamil from P.Muhlrad to J.Speith. [sdm 0109] | ||||||||
| Method | Gene |
