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WormBase Tree Display for Gene: WBGene00004882

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Name Class

WBGene00004882SMapS_parentSequenceF46B6
IdentityVersion1
NameCGC_namesmg-4Person_evidenceWBPerson261
Sequence_nameF46B6.3
Molecular_nameF46B6.3a
F46B6.3a.1
CE26973
F46B6.3b
CE30440
F46B6.3b.1
Other_namemab-14
CELE_F46B6.3Accession_evidenceNDBBX284605
Public_namesmg-4
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:36WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classsmg
Reference_alleleWBVar00088765
Allele (31)
Legacy_informationSee also ma116
[C.elegansII] ma116 : adult male has swollen bursa, adult hermaphrodite has protruding vulva. ME1. Recessive suppressor of unc-54(r293),tra-2(e1209), etc.; suppression reduced bymaternal rescue. unc-54 nonsense RNAs accumulate. OA3: r1181, e2615psu, e2616psu. Cloned: YAC and phage rescue. [Hodgkin et al. 1989; Pulak and Anderson 1993; CB; TR]
StrainWBStrain00034951
WBStrain00004551
WBStrain00004567
WBStrain00051118
WBStrain00055592
WBStrain00055594
WBStrain00055593
RNASeq_FPKM (74)
GO_annotation (13)
Contained_in_operonCEOP5236
Ortholog (30)
Structured_descriptionAutomated_descriptionPredicted to enable mRNA binding activity. Involved in male genitalia development; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; and obsolete hermaphrodite genitalia development. Located in nucleus and perinuclear region of cytoplasm. Expressed in intestinal cell; muscle cell; and neurons. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability 14. Is an ortholog of human UPF3A (UPF3A regulator of nonsense mediated mRNA decay) and UPF3B (UPF3B regulator of nonsense mediated mRNA decay).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0060821Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:20439)
Molecular_infoCorresponding_CDSF46B6.3a
F46B6.3b
Corresponding_CDS_historyF46B6.3:wp46
F46B6.3:wp69
F46B6.3b:wp76
Corresponding_transcriptF46B6.3a.1
F46B6.3b.1
Other_sequenceCBC05396_1
Associated_featureWBsf234278
WBsf234279
Experimental_infoRNAi_resultWBRNAi00094500Inferred_automaticallyRNAi_primary
WBRNAi00008069Inferred_automaticallyRNAi_primary
WBRNAi00047495Inferred_automaticallyRNAi_primary
WBRNAi00085061Inferred_automaticallyRNAi_primary
WBRNAi00094403Inferred_automaticallyRNAi_primary
WBRNAi00015065Inferred_automaticallyRNAi_primary
WBRNAi00047493Inferred_automaticallyRNAi_primary
WBRNAi00094395Inferred_automaticallyRNAi_primary
Expr_patternExpr110
Expr1337
Expr1022685
Expr1032421
Expr1151332
Expr2015910
Expr2034143
Drives_constructWBCnstr00010227
WBCnstr00035343
Construct_productWBCnstr00035343
AntibodyWBAntibody00001272
Microarray_results (28)
Expression_cluster (112)
Interaction (50)
Map_infoMapVPosition2.19411Error0.006525
Well_ordered
PositiveInside_rearreDf1
Positive_cloneF46B6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_data2_point3387
Multi_point1192
3101
3102
5376
Pos_neg_data4574
4575
Reference (38)
MethodGene