WormBase Tree Display for Gene: WBGene00004827

WBGene00004827 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: K08H2
  Identity: Version: 1
    Name: CGC_name: skr-21 Person_evidence: WBPerson322
      Sequence_name: K08H2.1
      Molecular_name: K08H2.1
        K08H2.1.1
        CE06159
      Other_name: CELE_K08H2.1 Accession_evidence: NDB BX284606
      Public_name: skr-21
    DB_info: Database: AceView gene XN844
        WormQTL gene WBGene00004827
        WormFlux gene WBGene00004827
        NDB locus_tag CELE_K08H2.1
        Panther gene CAEEL|WormBase=WBGene00004827|UniProtKB=Q21367
          family PTHR11165
        NCBI gene 54162166
        RefSeq protein NM_001381130.1
        TREEFAM TREEFAM_ID TF300142
        TrEMBL UniProtAcc Q21367
        UniProt_GCRP UniProtAcc Q21367
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:36 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: skr
    Allele (13)
    RNASeq_FPKM (74)
    GO_annotation: 00071444
      00071445
      00071446
      00071447
      00113233
    Ortholog (22)
    Paralog (20)
    Structured_description: Concise_description: The skr-21 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-21(RNAi) animals are at least superficially normal. Paper_evidence: WBPaper00005128
            WBPaper00005129
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: K08H2.1
    Corresponding_transcript: K08H2.1.1
    Other_sequence: CRC09334_1
      CBC13717_1
      CGC01386_1
      CR05264
    Associated_feature: WBsf654514
      WBsf654515
      WBsf1007569
      WBsf1024207
      WBsf238111
      WBsf238112
      WBsf238113
      WBsf238114
  Experimental_info: RNAi_result: WBRNAi00086808 Inferred_automatically: RNAi_primary
      WBRNAi00069098 Inferred_automatically: RNAi_primary
      WBRNAi00094811 Inferred_automatically: RNAi_primary
      WBRNAi00086800 Inferred_automatically: RNAi_primary
      WBRNAi00034168 Inferred_automatically: RNAi_primary
      WBRNAi00050351 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1028200
      Expr1032402
      Expr1154054
      Expr2015849
      Expr2034082
    Drives_construct: WBCnstr00035359
    Construct_product: WBCnstr00035359
    Microarray_results (15)
    Expression_cluster: WBPaper00028451:Oogenic_protein
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:dopaminergic-neurons_larva_enriched
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:Harposporium_24hr_downregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_downregulated_TilingArray
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00042561:smg-2(RNAi)_downregulated
      WBPaper00042561:smgl-1(RNAi)_downregulated
      WBPaper00044260:1-methylnicotinamide_downregulated
      WBPaper00044260:nicotic-acid_downregulated
      WBPaper00044316:CH3HgCl_7.5uM_downregulated
      WBPaper00044426:rotenone_5day_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045390:ubc-9(RNAi)_downregulated
      WBPaper00045417:128Q-huntingtin_downreglated
      WBPaper00045521:Oogenic
      WBPaper00045729:gld-2(RNAi)_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00048988:neuron_expressed
      WBPaper00049098:heat-induced_hrde-1(tm1200)
      WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
      WBPaper00049954:BPS_upregulated
      WBPaper00050163:chd-3(eh4)_upregulated_24-cell-embryo
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:daf-2(e1370)_vs_daf-2(e1370);mir-34(gk437)_regulated_dauer_25C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050903:mir-35-41(nDf50)_25C_downregulated
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00051352:Long-Term-Association-Memory_upregulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053321:embryo-to-L1_downregulated_nos-1(gv5)nos-2(RNAi)_SMARTseq
      WBPaper00053321:PGCs_depleted_NuGen
      WBPaper00053388:dauer_regulated_Cluster4
      WBPaper00053599:female_vs_male_upregulated
      WBPaper00053599:mitosis_vs_meiosis_downregulated
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053814:15C_downregulated_OP50
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055226:ADR-2_target_adr-1(tm668)
      WBPaper00055354:Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Metformin_upregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055386:eat-2(ad465)_downregulated
      WBPaper00055827:daf-2(e1370)_upregulated
      WBPaper00055827:pfd-6(gk493446)_upregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055971:nhl-2(ok818)_20C_upregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056161:hermaphrodite_enriched_siRNA
      WBPaper00056167:Cry5B_upregulated
      WBPaper00056284:ints-1(RNAi)_downregulated
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056443:DietaryRestriction_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056619:CEPsh_enriched
      WBPaper00056826:SGP_biased
      WBPaper00057006:DietaryRestriction_downregulated
      WBPaper00057068:Cadmium_upregulated
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058691:cfp-1(tm6369)_downregulated
      WBPaper00058691:sin-3(tm1276)_downregulated
      WBPaper00059224:tph-1(mg280)_upregulated
      WBPaper00059334:sacy-1(depletion)_regulated
      WBPaper00059471:EGL-43_interacting
      WBPaper00059763:neuron_expressed
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060459:bcat-1(RNAi)_downregulated
      WBPaper00060526:plp-1(ok2155)_downregulated
      WBPaper00060634:fhod-1(tm2363)_upregulated
      WBPaper00060764:swsn-1(os22ts)_downregulated
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00060921:tdc-1(n3419)_downregulated
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061274:microgravity_upregulated
      WBPaper00061340:ABarpaaa_lineage
      WBPaper00061340:ADA_ADE_grandparent
      WBPaper00061340:ADL_parent
      WBPaper00061340:AIN_parent
      WBPaper00061340:AMso_parent
      WBPaper00061340:AVH_parent
      WBPaper00061340:Ciliated_amphid_neuron
      WBPaper00061340:Ciliated_non_amphid_neuron
      WBPaper00061340:g2_parent
      WBPaper00061340:Glia
      WBPaper00061340:I1_parent
      WBPaper00061340:I2_grandparent
      WBPaper00061340:IL1_parent
      WBPaper00061340:M1_parent
      WBPaper00061340:Neuroblast_ADE_ADA
      WBPaper00061340:Neuroblast_AFD_RMD
      WBPaper00061340:Neuroblast_ALA_RMED
      WBPaper00061340:Neuroblast_ASG_AWA
      WBPaper00061340:Neuroblast_ASH_RIB
      WBPaper00061340:Neuroblast_AVG_RIR
      WBPaper00061340:Neuroblast_AWC_SAAVx
      WBPaper00061340:Neuroblast_BAG_SMDVx
      WBPaper00061340:Neuroblast_HSN_PHB
      WBPaper00061340:Neuroblast_IL1_IL2
      WBPaper00061340:Neuroblast_M2_M3
      WBPaper00061340:Neuroblast_PVC_LUA
      WBPaper00061340:NSM_parent
      WBPaper00061340:OLL_parent
      WBPaper00061340:Parents_of_U_F_B_DVA
      WBPaper00061340:Parents_of_Y_DA6_DA7_DA9
      WBPaper00061340:Parent_of_exc_duct_pore_DB_1_3
      WBPaper00061340:Parent_of_hyp1V_and_ant_arc_V
      WBPaper00061340:Parent_of_hyp3_ILsoDx
      WBPaper00061340:Parent_of_K_Kprime
      WBPaper00061340:Pharyngeal_neuron
      WBPaper00061340:RIA_parent
      WBPaper00061340:RID_parent
      WBPaper00061340:RIM_parent
      WBPaper00061340:RME_LR_parent
      WBPaper00061340:URA_parent
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061424:Diet_MYb120_downregulated
      WBPaper00061424:Diet_MYb131_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061527:cfz-2_18944-cfz-2_2268
      WBPaper00061527:utx-1_2886-swan-1_2192
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00061952:daf-18(yh1)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_upregulated_N2
      WBPaper00062440:crh-1(n3315)_downregulated
      WBPaper00062456:doxycycline_downregulated_CB4856_transcript
      WBPaper00062497:xpf-1(tm2842)_upregulated
      WBPaper00062585:hlh-26(ok1453)_downregulated_E.faecium
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064156:lbp-3(overexpress)_downregulated
      WBPaper00064156:lipl-4(overexpress)_downregulated
      WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064532:pals-22(jy3)_upregulated
      WBPaper00064632:daf-2(e1370)_upregulated_intestine
      WBPaper00064716:paraquat_upregulated
      WBPaper00064769:him-17(me24)_downregulated
      WBPaper00064871:hypoxia_downregulated_F2
      WBPaper00064999:miR-229-64-65-66_upregulated
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C
      WBPaper00065158:25C_vs_15C_upregulated_AFD
      WBPaper00065158:25C_vs_15C_upregulated_WholeAnimal
      WBPaper00065749:endu-2(tm4977)_upregulated
      WBPaper00065835:Day11_vs_Day1_upregulated
      WBPaper00065841:41_1
      WBPaper00065841:41_2
      WBPaper00065841:74_0
      WBPaper00065841:94_0
      WBPaper00065841:112_0
      WBPaper00065975:P-body_vs_WholeAnimal_enriched
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066038:mip-1(how5)_downregulated
      WBPaper00066093:E.coli-purE_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4386_cluster_6_2
      cgc4489_group_9
      WBPaper00024393:strongly_regulated_dauer_genes
      WBPaper00025032:cluster_2
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00034739:N2lessDR1350
      WBPaper00035227:heat_shock_regulated
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:osm-11_regulated
      WBPaper00036383:ash-2_Day8_regulated
      WBPaper00038231:Cry5B_1.5-fold_upregulated
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040963:Q50_down
      WBPaper00040963:Q100_down
      WBPaper00040963:Q200_down
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HF_11d_2.0mM_Down
      WBPaper00041174:environmental
      WBPaper00041174:genotype_environment_interaction
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041906:I-3690_vs_OP50_3d
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00041960:daf-16_fasting_upregulated
      WBPaper00041960:kgb-1_fasting_upregulated
      WBPaper00041960:N2_fasting_upregulated
      WBPaper00041960:N2_fasting_upregulated_9hto12h
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00042258:DA1877_downregulated_GravidAdult
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00046639:tyrosol_upregulated
      WBPaper00048989:N2_allantoin_upregulated
      WBPaper00050767:Octopamine_induced
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc5767]:cluster_5
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(66_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
    Interaction (165)
  Map_info: Map: X Position: 10.416
    Positive: Positive_clone: K08H2 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene