WormBase Tree Display for Gene: WBGene00004728

WBGene00004728 SMap: S_parent: Sequence: F21H11
  Identity: Version: 2
    Name: CGC_name: sax-2 Person_evidence: WBPerson42
      Sequence_name: F21H11.2
      Molecular_name: F21H11.2a
        F21H11.2a.1
        CE38067
        F21H11.2b
        CE38068
        F21H11.2b.1
      Other_name: CELE_F21H11.2 Accession_evidence: NDB BX284603
      Public_name: sax-2
    DB_info: Database: AceView gene 3G219
        WormQTL gene WBGene00004728
        WormFlux gene WBGene00004728
        NDB locus_tag CELE_F21H11.2
        Panther gene CAEEL|WormBase=WBGene00004728|UniProtKB=Q5DX48
          family PTHR12295
        NCBI gene 175697
        RefSeq protein NM_171118.6
            NM_171117.5
        TREEFAM TREEFAM_ID TF313568
        TrEMBL UniProtAcc Q5DX48
            H2KZU6
        UniProt_GCRP UniProtAcc Q5DX48
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:36 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 26 Nov 2004 09:02:28 WBPerson2970 Event: Acquires_merge: WBGene00017682
      Acquires_merge: WBGene00017682
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: sax
    Allele (298)
    Strain: WBStrain00005244
    RNASeq_FPKM (74)
    GO_annotation: 00022537
      00022538
      00022539
      00022540
      00022541
      00113102
    Ortholog (54)
    Structured_description: Concise_description: sax-2 encodes a conserved protein that contains HEAT/Armadillo repeats and is related to Drosophila furry; sax-2 activity is required for maintaining normal neuronal morphology, particularly proper neurite outgrowth and termination; sax-2 activity is also required for normal male mating behavior and gonad morphogenesis in both sexes; a sax-2 reporter gene fusion indicates that sax-2 is expressed in head, tail, and ventral cord neurons. Paper_evidence: WBPaper00003665
            WBPaper00004340
            WBPaper00024477
            WBPaper00027335
          Curator_confirmed: WBPerson1843
          Date_last_updated: 24 Jan 2008 00:00:00
      Automated_description: Involved in neuron projection development. Predicted to be located in cell cortex and site of polarized growth. Expressed in head neurons; tail neurons; and ventral nerve cord. Is an ortholog of human FRY (FRY microtubule binding protein) and FRYL (FRY like transcription coactivator). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F21H11.2a
      F21H11.2b
    Corresponding_CDS_history: F21H11.2a:wp138
      F21H11.2b:wp138
    Corresponding_transcript: F21H11.2a.1
      F21H11.2b.1
    Other_sequence (24)
    Associated_feature (23)
  Experimental_info: RNAi_result (13)
    Expr_pattern: Expr3110
      Expr1020311
      Expr1032332
      Expr1149172
      Expr2015607
      Expr2033842
    Drives_construct: WBCnstr00035425
    Construct_product: WBCnstr00035425
    Microarray_results (27)
    Expression_cluster (155)
    Interaction (38)
  Map_info: Map: III Position: -2.13133 Error: 0.008596
    Positive: Positive_clone: F21H11 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4046
        4725
  Reference (29)
  Remark: Description and Allele (ky216) data extracted from Zallen JA, Kirch SA, Bargmann CI [ck1 020828]
  Method: Gene