WormBase Tree Display for Gene: WBGene00004374

WBGene00004374 SMap: S_parent: Sequence: T11F8
  Identity: Version: 1
    Name: CGC_name: rme-2 Person_evidence: WBPerson259
      Sequence_name: T11F8.3
      Molecular_name: T11F8.3a
        T11F8.3a.1
        CE22368
        T11F8.3b
        CE49356
        T11F8.3b.1
      Other_name: CELE_T11F8.3 Accession_evidence: NDB BX284604
      Public_name: rme-2
    DB_info: Database: AceView gene 4G237
        WormQTL gene WBGene00004374
        WormFlux gene WBGene00004374
        NDB locus_tag CELE_T11F8.3
        Panther gene CAEEL|WormBase=WBGene00004374|UniProtKB=O44191
          family PTHR46513
        NCBI gene 177329
        RefSeq protein NM_068414.7
            NM_001380231.1
        TrEMBL UniProtAcc V6CIR8
            O44191
        UniProt_GCRP UniProtAcc O44191
        OMIM gene 131530
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:35 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info (11)
  Disease_info: Potential_model (21)
  Modifies_disease: DOID:14175
  Modifies_disease_in_annotation: WBDOannot00000601
  Molecular_info: Corresponding_CDS: T11F8.3a
      T11F8.3b
    Corresponding_CDS_history: T11F8.3:wp86
    Corresponding_transcript: T11F8.3a.1
      T11F8.3b.1
    Other_sequence (30)
    Associated_feature (12)
  Experimental_info: RNAi_result (35)
    Expr_pattern (11)
    Drives_construct: WBCnstr00001790
      WBCnstr00035528
    Construct_product: WBCnstr00001790
      WBCnstr00035528
    Antibody: WBAntibody00000259
      WBAntibody00000260
      WBAntibody00001446
      WBAntibody00001603
      WBAntibody00001930
      WBAntibody00002024
    Microarray_results (22)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00033065:isp-1-1(qm150)_upregulated
      WBPaper00035073:mitochondria_protein
      WBPaper00037047:aging_accelerated_insoluble_protein
      WBPaper00037047:insoluble_protein
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:pharyngeal-muscle_embryo_enriched
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00038168:lin-15B(n744)_upregulated
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00041954:ethanol_upregulated
      WBPaper00042477:rsr-2(RNAi)_downregulated_TilingArray
      WBPaper00044037:eat-2_downregulated
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:rising_dev_expression
      WBPaper00044786:emr-1(gk119)_downregulated
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated
      WBPaper00045050:csr-1(hypomorph)_downregulated
      WBPaper00045050:drh-3 (ne4253)_downregulated
      WBPaper00045316:prg-1_downregulated_L4
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Oogenic
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00045618:fbf-1_downregulated
      WBPaper00045618:puf-8_downregulated
      WBPaper00046012:tdp-1(ok803)_downregulated
      WBPaper00046337:monosomal_N2_vs_daf-2_upregulated
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_upregulated
      WBPaper00046337:polysomal_N2_vs_daf-2_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046691:P1_enriched
      WBPaper00046795:starvation_downregulated
      WBPaper00048579:aging_downregulated
      WBPaper00048611:MnCl2_downregulated
      WBPaper00048762:FOG-1_associated
      WBPaper00048762:FOG-3_associated
      WBPaper00048988:neuron_expressed
      WBPaper00049920:Glucose-Diet_downregulated_N2
      WBPaper00049942:HeatShock_upregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00049954:BPA_downregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_24-cell-embryo
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050522:mafr-1(tm6082)_downregulated
      WBPaper00050686:glp-1(e2141)_downregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:downregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:downregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051265:F1_morc-1(tm6048)_downregulated
      WBPaper00051265:F4_morc-1(tm6048)_upregulated
      WBPaper00051437:Cit-SPIONs_upregulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053154:human-amyloid-beta_tau_regulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053295:lin-22(icb38)_downregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:PGCs_enriched_NuGen
      WBPaper00053599:female_vs_male_upregulated
      WBPaper00053599:mitosis_vs_meiosis_downregulated
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
      WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_upregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_downregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00054493:hpl-2(tm1489)_downregulated
      WBPaper00054792:FOG-3_interacting
      WBPaper00055013:hmg-3(bar24)_upregulated
      WBPaper00055049:S.gordonii_downregulated
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055354:Rapamycin-Allantoin_upregulated
      WBPaper00055354:Rapamycin_upregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055364:uaf-1(n4588)_upregulated
      WBPaper00055482:pmt-2(RNAi)_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00055804:FBF-1-FBF-2-associated_oogenic-enriched
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055941:atfs-1(et15)_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056161:hermaphrodite_enriched_siRNA
      WBPaper00056169:rrf-3(pk1426)_downregulated_embryo
      WBPaper00056169:rrf-3(pk1426)_upregulated_L4
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056290:hsp-6(mg585)_downregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056826:hmc_biased
      WBPaper00056997:nmad-1(ok3133)_downregulated_germline_25C
      WBPaper00057006:DietaryRestriction_downregulated
      WBPaper00057154:HeatShock_downregulated_mRNA
      WBPaper00057288:Cold_downregulated_protein
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058691:cfp-1(tm6369)_upregulated
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00058948:PA14_upregulated
      WBPaper00059174:MEG-3_interacting
      WBPaper00059605:MUT-16_interacting
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00059739:hira-1(gk835598)_upregulated_L4
      WBPaper00060014:set-2(zr2012)_downregulated
      WBPaper00060100:SiNP_upregulated_mRNA
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060445:ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060459:bcat-1(RNAi)_downregulated
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00061007:HB101_downregulated
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061045:Y56A3A.22(cck200)_downregulated
      WBPaper00061340:Germline
      WBPaper00061340:PVR
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061478:SUMO-conjugated_protein
      WBPaper00061479:HDA-1_interacting_protein
      WBPaper00061527:T24D1.3-egg-1
      WBPaper00061753:csr-1(tor159)_downregulated_25C
      WBPaper00062056:lin-35(n745)_upregulated
      WBPaper00062118:neural-HSF-1_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062446:nhr-8(hd117)_downregulated
      WBPaper00062456:doxycycline_downregulated_CB4856_protein
      WBPaper00062456:doxycycline_downregulated_CB4856_transcript
      WBPaper00062456:doxycycline_downregulated_N2_protein
      WBPaper00062497:xpf-1(tm2842)_downregulated
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064005:starvation_downregulated_aptf-1(gk794)_protein
      WBPaper00064005:starvation_upregulated_N2_protein
      WBPaper00064055:trl-1(cas1077)_upregulated_non-starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064163:ZNFX-1_interacting_embryo
      WBPaper00064163:ZNFX-1_interacting_young-adult
      WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated
      WBPaper00064403:Heat-killed-E.Coli_upregulated
      WBPaper00064505:tamoxifen_upregulated
      WBPaper00064532:pals-25(icb98)_upregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00064735:bet-1(uth41)_vs_N2_downregulated
      WBPaper00064769:him-17(me24)_downregulated
      WBPaper00064871:hypoxia_upregulated_F1
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065096:npr-8(ok1439)_downregulated_Day1_25C
      WBPaper00065096:npr-8(ok1439)_upregulated_Day1_20C
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065132:asna-1(ok938)_downregulated_protein
      WBPaper00065288:mdt-15(tm2182)_upregulated
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_upregulated_Ref
      WBPaper00065926:pgph-2(overepxreesion)_upregulated
      WBPaper00065984:pals-17(syb3980)_upregulated
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066085:hda-3(ok1991)_downregulated
      WBPaper00066085:sin-3(syb2172)_downregulated
      WBPaper00066110:Doxorubicin_downregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4386_cluster_3_1
      cgc4489_group_2
      cgc4489_group_9
      WBPaper00025032:cluster_41
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00027758:Group_I
      WBPaper00028948:cep-1(gk138)+UV_upregulated
      WBPaper00030985:Enterococcus_faecalis_downregulated
      WBPaper00032165:differentially_expressed_with_age_medoid_5
      WBPaper00035479:daf-16(RNAi)_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_F
      WBPaper00037611:RNP-8-associated
      WBPaper00037901:GLD-1_mRNA_targets
      WBPaper00038060:SUMO-1_upregulated
      WBPaper00038172:aak-2overexpression_up_regulated
      WBPaper00040210:Diazinon_24C_regulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040963:TA100_down
      WBPaper00040963:TA300_down
      WBPaper00041002:HF_11d_2.0mM_Up
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00046548:dafachronic-acid_downregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00051387:Triclosan_downregulated
      WBPaper00055435:AuNPs_downregulated
      WBPaper00056330:mrps-5(RNAi)_downregulated
      [cgc5767]:cluster_1
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_MD_pd(PC32)
      [cgc5767]:expression_class_SM
      [cgc5767]:expression_class_SMD
      [cgc6390]:Cluster_E
      [cgc6390]:intrinsic
    Interaction (376)
    WBProcess: WBbiopr:00000068
  Map_info: Map: IV Position: 1.68692 Error: 0.007682
    Well_ordered
    Positive: Inside_rearr: mDf4
        nDf41
      Positive_clone: T11F8 Author_evidence: sequence alterations,
          Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 3827
        3828
        3829
        4614
      Pos_neg_data: 10282
        10284
  Reference (82)
  Method: Gene