WormBase Tree Display for Gene: WBGene00004324
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| WBGene00004324 | SMap | S_parent | Sequence | F21C3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | rde-2 | Person_evidence | WBPerson419 | |||||
| Sequence_name | F21C3.4 | ||||||||
| Molecular_name | F21C3.4a | ||||||||
| F21C3.4a.1 | |||||||||
| CE37005 | |||||||||
| F21C3.4b | |||||||||
| CE38174 | |||||||||
| F21C3.4b.1 | |||||||||
| Other_name | mut-8 | Paper_evidence | WBPaper00003956 | ||||||
| Person_evidence | WBPerson2587 | ||||||||
| CELE_F21C3.4 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | rde-2 | ||||||||
| DB_info | Database | WormQTL | gene | WBGene00004324 | |||||
| WormFlux | gene | WBGene00004324 | |||||||
| NDB | locus_tag | CELE_F21C3.4 | |||||||
| NCBI | gene | 172473 | |||||||
| RefSeq | protein | NM_001026227.3 | |||||||
| NM_001026228.4 | |||||||||
| TrEMBL | UniProtAcc | Q19672 | |||||||
| Q58AA4 | |||||||||
| UniProt_GCRP | UniProtAcc | Q19672 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 14 Jan 2005 10:37:35 | WBPerson2970 | Event | Acquires_merge | WBGene00003505 | ||||
| 3 | 14 Jan 2005 10:41:26 | WBPerson2970 | Event | Acquires_merge | WBGene00009003 | ||||
| Acquires_merge | WBGene00003505 | ||||||||
| WBGene00009003 | |||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rde | ||||||||
| Allele (31) | |||||||||
| Strain | WBStrain00029016 | ||||||||
| WBStrain00040416 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00065442 | ||||||||
| 00065443 | |||||||||
| 00065444 | |||||||||
| 00065445 | |||||||||
| 00065446 | |||||||||
| 00065447 | |||||||||
| 00065448 | |||||||||
| 00065449 | |||||||||
| 00065450 | |||||||||
| Contained_in_operon | CEOP1384 | ||||||||
| Ortholog (20) | |||||||||
| Structured_description | Concise_description | rde-2 encodes a novel protein that is conserved in at least two other Caenorhabditis species; rde-2 is required for the functional silencing of chromosomal loci by transgenes (cosuppression) and promotes the effects of RNAi in a step after the formation of a heritable interfering agent, also affects X-chromosome nondisjunction and transposon activation; functions downstream of rde-1 in the RNAi pathway most effective against germline, but not somatically expressed, genes; RDE-2 is present predominantly in the cytosol, in complexes with MUT-7, a predicted exoribonuclease also required for RNA interference. | Paper_evidence | WBPaper00003711 | |||||
| WBPaper00003964 | |||||||||
| WBPaper00004198 | |||||||||
| WBPaper00005368 | |||||||||
| WBPaper00024699 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 22 Feb 2006 00:00:00 | ||||||||
| Automated_description | Involved in several processes, including meiotic chromosome segregation and regulatory ncRNA-mediated gene silencing. Located in cytosol and mutator focus. Expressed in germ line. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F21C3.4a | |||||||
| F21C3.4b | |||||||||
| Corresponding_CDS_history | F21C3.4:wp47 | ||||||||
| F21C3.4:wp128 | |||||||||
| Corresponding_transcript | F21C3.4a.1 | ||||||||
| F21C3.4b.1 | |||||||||
| Other_sequence | CBC00924_1 | ||||||||
| Associated_feature | WBsf219729 | ||||||||
| WBsf219730 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00086733 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00003411 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00061788 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00003412 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00092968 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00076321 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00086728 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00031209 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00116531 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00045182 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr10156 | ||||||||
| Expr1018003 | |||||||||
| Expr1032149 | |||||||||
| Expr1149122 | |||||||||
| Expr2015285 | |||||||||
| Expr2033519 | |||||||||
| Drives_construct | WBCnstr00014701 | ||||||||
| WBCnstr00014703 | |||||||||
| Construct_product | WBCnstr00014701 | ||||||||
| WBCnstr00014703 | |||||||||
| Antibody | WBAntibody00000829 | ||||||||
| Microarray_results (25) | |||||||||
| Expression_cluster (112) | |||||||||
| Interaction (33) | |||||||||
| Map_info | Map | I | Position | 1.87282 | Error | 0.000485 | |||
| Positive | Positive_clone | F21C3 | Inferred_automatically | From From sequence, transcript, pseudogene data | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 5087 | |||||||
| 4953 | |||||||||
| 5331 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (51) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
