WormBase Tree Display for Gene: WBGene00004270
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| WBGene00004270 | SMap | S_parent | Sequence | T25G12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | rab-6.2 | Person_evidence | WBPerson451 | |||||
| Sequence_name | T25G12.4 | ||||||||
| Molecular_name | T25G12.4 | ||||||||
| T25G12.4.1 | |||||||||
| CE07541 | |||||||||
| Other_name | CELE_T25G12.4 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | rab-6.2 | ||||||||
| DB_info | Database | AceView | gene | XR837 | |||||
| WormQTL | gene | WBGene00004270 | |||||||
| WormFlux | gene | WBGene00004270 | |||||||
| NDB | locus_tag | CELE_T25G12.4 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004270|UniProtKB=Q22782 | |||||||
| family | PTHR24073 | ||||||||
| NCBI | gene | 181759 | |||||||
| RefSeq | protein | NM_078389.7 | |||||||
| SwissProt | UniProtAcc | Q22782 | |||||||
| TREEFAM | TREEFAM_ID | TF300803 | |||||||
| UniProt_GCRP | UniProtAcc | Q22782 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rab | ||||||||
| Allele (29) | |||||||||
| Strain | WBStrain00001717 | ||||||||
| WBStrain00001718 | |||||||||
| WBStrain00037087 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (36) | |||||||||
| Ortholog (50) | |||||||||
| Paralog (32) | |||||||||
| Structured_description | Concise_description | rab-6.2 encodes a small, monomeric Rab GTPase that is most closely related to the Drosophila and mammalian Rab6 GTPases; by homology, RAB-6.2 is predicted to function in the regulation of intracellular membrane trafficking; RNAi experiments indicate that rab-6.2 is required redundantly with rab-6.1 for normal embryonic development and reproduction; a RAB-6.2::GFP fusion protein localizes to the Golgi cisternae; RAB-6.2 physically interacts with VPS-52, a GARP (Golgi associated retrograde protein) complex subunit, in vivo. | Paper_evidence | WBPaper00030808 | |||||
| WBPaper00038455 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 13 Jan 2012 00:00:00 | ||||||||
| Automated_description | Enables GTP binding activity. Involved in several processes, including early endosome to Golgi transport; positive regulation of feeding behavior; and protein stabilization. Located in Golgi trans cisterna. Expressed in several structures, including coelomocyte; command interneuron; gonad; pharynx; and vulva. Is an ortholog of human RAB6A (RAB6A, member RAS oncogene family) and RAB6B (RAB6B, member RAS oncogene family). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T25G12.4 | |||||||
| Corresponding_transcript | T25G12.4.1 | ||||||||
| Other_sequence (50) | |||||||||
| Associated_feature | WBsf655243 | ||||||||
| WBsf1008841 | |||||||||
| WBsf1024977 | |||||||||
| WBsf236886 | |||||||||
| WBsf236887 | |||||||||
| WBsf236888 | |||||||||
| WBsf236889 | |||||||||
| WBsf236890 | |||||||||
| Experimental_info | RNAi_result (11) | ||||||||
| Expr_pattern (11) | |||||||||
| Drives_construct | WBCnstr00002541 | ||||||||
| WBCnstr00002542 | |||||||||
| WBCnstr00014399 | |||||||||
| WBCnstr00015514 | |||||||||
| WBCnstr00018181 | |||||||||
| WBCnstr00035597 | |||||||||
| Construct_product | WBCnstr00008290 | ||||||||
| WBCnstr00014399 | |||||||||
| WBCnstr00015121 | |||||||||
| WBCnstr00015514 | |||||||||
| WBCnstr00019185 | |||||||||
| WBCnstr00035597 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (151) | |||||||||
| Interaction (108) | |||||||||
| Map_info | Map | X | Position | 24.0866 | Error | 0.000393 | |||
| Positive | Positive_clone | T25G12 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 5259 | |||||||
| 4748 | |||||||||
| 5589 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (24) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
