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WormBase Tree Display for Gene: WBGene00004269

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Name Class

WBGene00004269SMapS_parentSequenceF59B2
IdentityVersion1
NameCGC_namerab-6.1Person_evidenceWBPerson451
Sequence_nameF59B2.7
Molecular_nameF59B2.7
F59B2.7.1
CE00234
Other_nameP34213Paper_evidenceWBPaper00041995
CELE_F59B2.7Accession_evidenceNDBBX284603
Public_namerab-6.1
DB_infoDatabaseAceViewgene3K94
WormQTLgeneWBGene00004269
WormFluxgeneWBGene00004269
NDBlocus_tagCELE_F59B2.7
PanthergeneCAEEL|WormBase=WBGene00004269|UniProtKB=P34213
familyPTHR24073
NCBIgene176275
RefSeqproteinNM_066592.7
SwissProtUniProtAccP34213
TREEFAMTREEFAM_IDTF300803
UniProt_GCRPUniProtAccP34213
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:34WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrab
Allele (22)
RNASeq_FPKM (74)
GO_annotation (29)
Ortholog (43)
Paralog (32)
Structured_descriptionConcise_descriptionrab-6.1 encodes a small, monomeric Rab GTPase that is most closely related to the Drosophila and mammalian Rab6 GTPases; by homology, RAB-6.1 is predicted to function in the regulation of intracellular membrane trafficking; RNAi experiments indicate that rab-6.1 is required redundantly with rab-6.2 for normal embryonic development and reproduction; a RAB-6.1::GFP fusion protein localizes to the Golgi cisternae; RAB-6.1 physically interacts with VPS-52, a GARP (Golgi associated retrograde protein) complex subunit, in vivo.Paper_evidenceWBPaper00030808
WBPaper00038455
Curator_confirmedWBPerson1843
Date_last_updated13 Jan 2012 00:00:00
Automated_descriptionPredicted to enable GTPase activity. Involved in cortical granule exocytosis and cuticle development. Located in Golgi cisterna and cortical granule. Expressed in several structures, including RIG; command interneuron; gonad; intestine; and vulva. Is an ortholog of human RAB6A (RAB6A, member RAS oncogene family).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF59B2.7
Corresponding_transcriptF59B2.7.1
Other_sequenceEL888321.1
XIC03786_1
Tcir_isotig14388
JI172655.1
PPC17073_1
CBC04025_1
XI03944
Associated_featureWBsf227222
Experimental_infoRNAi_result (14)
Expr_patternExpr9
Expr10203
Expr12748
Expr1017645
Expr1032108
Expr1152894
Expr2015229
Expr2033463
Drives_constructWBCnstr00015513
WBCnstr00022749
WBCnstr00035598
Construct_productWBCnstr00015122
WBCnstr00015123
WBCnstr00015513
WBCnstr00022747
WBCnstr00022748
WBCnstr00022749
WBCnstr00035598
Microarray_results (22)
Expression_cluster (126)
Interaction (102)
Map_infoMapIIIPosition0.082312Error0.009627
PositivePositive_cloneF59B2Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point5517
4764
4799
Pseudo_map_position
Reference (14)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene