WormBase Tree Display for Gene: WBGene00004192

WBGene00004192 SMap: S_parent: Sequence: ZK809
  Identity: Version: 1
    Name: CGC_name: prx-2
      Sequence_name: ZK809.7
      Molecular_name: ZK809.7
        ZK809.7.1
        CE40543
      Other_name: CELE_ZK809.7 Accession_evidence: NDB BX284604
      Public_name: prx-2
    DB_info: Database: AceView gene 4M411
        WormQTL gene WBGene00004192
        WormFlux gene WBGene00004192
        NDB locus_tag CELE_ZK809.7
        NCBI gene 178094
        RefSeq protein NM_069800.5
        TREEFAM TREEFAM_ID TF105312
        TrEMBL UniProtAcc Q23601
        UniProt_GCRP UniProtAcc Q23601
        OMIM gene 170993
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:34 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: prx
    Allele (19)
    RNASeq_FPKM (74)
    GO_annotation (11)
    Ortholog (29)
    Structured_description: Concise_description: prx-2 is orthologous to the human gene PEROXISOMAL MEMBRANE PROTEIN 3 (PXMP3; OMIM:170993), which when mutated leads to Zellweger syndrome 3 or infantile Refsum disease. Curator_confirmed: WBPerson1823
            WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable transferase activity and zinc ion binding activity. Predicted to be involved in protein import into peroxisome matrix. Predicted to be located in peroxisomal membrane. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 5A. Is an ortholog of human PEX2 (peroxisomal biogenesis factor 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080480 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9717)
      DOID:0080377 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9717)
  Molecular_info: Corresponding_CDS: ZK809.7
    Corresponding_CDS_history: ZK809.7:wp166
    Corresponding_transcript: ZK809.7.1
    Associated_feature: WBsf646399
      WBsf660747
      WBsf997895
      WBsf997896
      WBsf1018238
  Experimental_info: RNAi_result (19)
    Expr_pattern: Expr1016339
      Expr1032052
      Expr1163151
      Expr2015125
      Expr2033363
    Drives_construct: WBCnstr00035646
    Construct_product: WBCnstr00035646
    Microarray_results (16)
    Expression_cluster (90)
    Interaction (42)
  Map_info: Map: IV Position: 5.10274 Error: 0.002069
    Positive: Positive_clone: ZK809 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00005877
    WBPaper00006517
    WBPaper00026667
    WBPaper00027315
    WBPaper00031003
    WBPaper00038491
    WBPaper00055090
    WBPaper00056693
    WBPaper00059323
  Remark: Note that some Authors have incorrectly published prx genes as pex genes. pex genes are a separate class of gene not related to prx genes [JAH][030108 ck1]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene