WormBase Tree Display for Gene: WBGene00004192

WBGene00004192 SMap: S_parent: Sequence: ZK809
  Identity: Version: 1
    Name: CGC_name: prx-2
      Sequence_name: ZK809.7
      Molecular_name: ZK809.7
        ZK809.7.1
        CE40543
      Other_name: CELE_ZK809.7 Accession_evidence: NDB BX284604
      Public_name: prx-2
    DB_info: Database: AceView gene 4M411
        WormQTL gene WBGene00004192
        WormFlux gene WBGene00004192
        NDB locus_tag CELE_ZK809.7
        NCBI gene 178094
        RefSeq protein NM_069800.5
        TREEFAM TREEFAM_ID TF105312
        TrEMBL UniProtAcc Q23601
        UniProt_GCRP UniProtAcc Q23601
        OMIM gene 170993
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:34 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: prx
    Allele (19)
    RNASeq_FPKM (74)
    GO_annotation (11)
    Ortholog: WBGene00062604 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00073570 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00028435 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00145935 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            WormBase-Compara
      WBGene00194229 Caenorhabditis brenneri From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      CBOVI.g8242 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP26.g20556 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g573 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g658 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g7770 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g9904 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g13702 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g20908 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP39.g9737 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g763 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00011.g844 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-prx-2 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp5_scaffold_00092.g4017 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_21331 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_014133 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g08957 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g5726 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_40324600 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIV_pilon.g11901 Caenorhabditis elegans From_analysis: WormBase-Compara
      FB:FBgn0035876 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      ZFIN:ZDB-GENE-070530-2 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      HGNC:9717 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            PhylomeDB
      MGI:107486 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      RGD:61814 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
    Structured_description: Concise_description: prx-2 is orthologous to the human gene PEROXISOMAL MEMBRANE PROTEIN 3 (PXMP3; OMIM:170993), which when mutated leads to Zellweger syndrome 3 or infantile Refsum disease. Curator_confirmed: WBPerson1823
            WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable transferase activity and zinc ion binding activity. Predicted to be involved in protein import into peroxisome matrix. Predicted to be located in peroxisomal membrane. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 5A. Is an ortholog of human PEX2 (peroxisomal biogenesis factor 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080480 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9717)
      DOID:0080377 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9717)
  Molecular_info: Corresponding_CDS: ZK809.7
    Corresponding_CDS_history: ZK809.7:wp166
    Corresponding_transcript: ZK809.7.1
    Associated_feature: WBsf646399
      WBsf660747
      WBsf997895
      WBsf997896
      WBsf1018238
  Experimental_info: RNAi_result (19)
    Expr_pattern: Expr1016339
      Expr1032052
      Expr1163151
      Expr2015125
      Expr2033363
    Drives_construct: WBCnstr00035646
    Construct_product: WBCnstr00035646
    Microarray_results (16)
    Expression_cluster (90)
    Interaction (42)
  Map_info: Map: IV Position: 5.10274 Error: 0.002069
    Positive: Positive_clone: ZK809 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00005877
    WBPaper00006517
    WBPaper00026667
    WBPaper00027315
    WBPaper00031003
    WBPaper00038491
    WBPaper00055090
    WBPaper00056693
    WBPaper00059323
  Remark: Note that some Authors have incorrectly published prx genes as pex genes. pex genes are a separate class of gene not related to prx genes [JAH][030108 ck1]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene