The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
Enriched in anterior ganglion (ant); head mesodermal cell; hypodermis; interfacial epithelial cell; and mechanosensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-one chemicals including hydrogen sulfide; methylmercury hydroxide; and 1-methylnicotinamide based on microarray and RNA-seq studies.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.