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WormBase Tree Display for Gene: WBGene00004027

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Name Class

WBGene00004027SMapS_parentSequenceY49E10
IdentityVersion1
NameCGC_namepie-1Person_evidenceWBPerson498
Sequence_nameY49E10.14
Molecular_nameY49E10.14a
Y49E10.14a.1
CE28134
Y49E10.14b
CE45773
Y49E10.14b.1
Other_namepic-1
CELE_Y49E10.14Accession_evidenceNDBBX284603
Public_namepie-1
DB_infoDatabaseAceViewgene3N517
WormQTLgeneWBGene00004027
WormFluxgeneWBGene00004027
NDBlocus_tagCELE_Y49E10.14
PanthergeneCAEEL|WormBase=WBGene00004027|UniProtKB=Q94131
familyPTHR12547
NCBIgene176667
RefSeqproteinNM_001268238.3
NM_001268237.2
SwissProtUniProtAccQ94131
TREEFAMTREEFAM_IDTF318914
UniProt_GCRPUniProtAccQ94131
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpie
Allele (78)
Legacy_information[C.elegansII] zu154 : maternal effect lethal, often with two distinct pharynges; additional pharynx and intestinal tissue from P2 (transformed to EMS fate).OA1. Cloned: encodes zinc finger protein, localized to nuclei of germ line blastomeres. [Mello et al. 1992; Mango et al. 1994; EU; JJ]
StrainWBStrain00000051
WBStrain00000054
WBStrain00000344
WBStrain00000345
WBStrain00000347
WBStrain00000348
WBStrain00000349
WBStrain00000350
WBStrain00007241
WBStrain00022176
WBStrain00022243
WBStrain00022248
WBStrain00022249
WBStrain00022250
WBStrain00022252
WBStrain00022253
WBStrain00022257
WBStrain00022258
WBStrain00022322
WBStrain00022323
WBStrain00022324
WBStrain00022325
WBStrain00022326
WBStrain00022327
WBStrain00022328
WBStrain00022329
WBStrain00022330
WBStrain00023577
WBStrain00023578
WBStrain00029017
WBStrain00029019
WBStrain00029177
WBStrain00029208
WBStrain00029210
WBStrain00029211
WBStrain00029212
WBStrain00029213
WBStrain00029214
WBStrain00029217
WBStrain00029218
WBStrain00029220
WBStrain00029221
WBStrain00029222
WBStrain00029226
WBStrain00029227
WBStrain00029228
WBStrain00029229
WBStrain00029230
WBStrain00029231
WBStrain00033545
WBStrain00034444
WBStrain00034450
WBStrain00034458
WBStrain00034707
WBStrain00034708
WBStrain00034710
WBStrain00034711
WBStrain00034713
WBStrain00034719
WBStrain00035074
WBStrain00035075
WBStrain00035077
WBStrain00035078
WBStrain00035079
WBStrain00035080
WBStrain00035085
WBStrain00040371
WBStrain00040382
WBStrain00040383
WBStrain00040388
WBStrain00022474
WBStrain00007105
WBStrain00007250
WBStrain00040389
WBStrain00050674
WBStrain00051046
RNASeq_FPKM (74)
GO_annotation (33)
Ortholog (26)
Paralog (20)
Structured_descriptionConcise_descriptionpie-1 encodes a C-x8-C-x5-C-x3-H-type zinc-finger protein; maternally provided PIE-1 is essential for germline cell fate determination, as it functions as a repressor of RNA polymerase II-dependent gene expression in the developing germ line; PIE-1 localization, initially uniform and then concentrated in the posterior germ cell lineages, is regulated by other maternally supplied gene products including PAR-1, MEX-5, and MEX-6.Paper_evidenceWBPaper00004304
WBPaper00004631
WBPaper00005297
WBPaper00005347
WBPaper00005605
WBPaper00005735
WBPaper00005791
Curator_confirmedWBPerson1843
Date_last_updated30 Nov 2004 00:00:00
Automated_descriptionPredicted to enable mRNA 3'-UTR binding activity. Involved in several processes, including embryonic pattern specification; formation of primary germ layer; and negative regulation of nitrogen compound metabolic process. Located in several cellular components, including P granule; centrosome; and cytosol. Expressed in germ line; head muscle; and nerve ring.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY49E10.14a
Y49E10.14b
Corresponding_CDS_historyY49E10.14:wp52
Corresponding_transcriptY49E10.14a.1
Y49E10.14b.1
Other_sequenceU62896
CBC08706_1
CRC03076_1
Associated_featureWBsf047506
WBsf645660
WBsf659608
WBsf976032
WBsf976033
WBsf976034
WBsf978688
WBsf994644
WBsf225904
Transcription_factorWBTranscriptionFactor000460
Experimental_infoRNAi_result (65)
Expr_pattern (17)
Drives_construct (720)
Construct_product (18)
Regulate_expr_clusterWBPaper00061478:pie-1(ne4303)_upregulated
WBPaper00061478:pie-1(ne4433)_upregulated
AntibodyWBAntibody00000118
WBAntibody00000189
WBAntibody00000697
WBAntibody00001076
WBAntibody00001395
WBAntibody00001588
WBAntibody00001589
Microarray_results (24)
Expression_cluster (152)
Interaction (309)
WBProcessWBbiopr:00000017
Map_infoMapIIIPosition17.7453Error0.045821
Well_ordered
PositiveInside_rearrctDf3
Positive_clonepJP604
Y49E10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point (11)
Pos_neg_data8413
8414
8548
8557
Landmark_gene
Reference (314)
MethodGene