WormBase Tree Display for Gene: WBGene00004015
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WBGene00004015 | SMap | S_parent | Sequence | T24H7 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | phb | ||||||
Allele (14) | |||||||
Strain | WBStrain00002997 | ||||||
WBStrain00005595 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (26) | |||||||
Ortholog (43) | |||||||
Paralog | WBGene00004014 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | |||||||
Structured_description | Concise_description | phb-2 encodes the C. elegans ortholog of prohibitin PHB2; loss of phb-2 activity via RNAi indicates that phb-2 function is required for mitochondrial organization and morphology and for embryonic, germline, and somatic gonad development; PHB-2, along with prohibitin subunit PHB-1, forms a macromolecular complex that localizes to mitochondrial membranes; PHB-1 and PHB-2 are dependent upon one another for stability: loss of either phb-1 or phb-2 activity via RNAi results in depletion of both protein products. | Paper_evidence | WBPaper00006039 | |||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 20 Dec 2010 00:00:00 | ||||||
Automated_description | Predicted to enable protein homodimerization activity. Involved in several processes, including defecation; developmental process involved in reproduction; and mitochondrion organization. Located in mitochondrial membrane. Part of mitochondrial prohibitin complex. Expressed in body wall musculature; excretory canal; hypodermis; intestine; and neurons. Is an ortholog of human PHB2 (prohibitin 2). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | T24H7.1 | |||||
Corresponding_CDS_history | T24H7.1:wp171 | ||||||
Corresponding_transcript | T24H7.1.1 | ||||||
Other_sequence (133) | |||||||
Associated_feature | WBsf654875 | ||||||
WBsf657672 | |||||||
WBsf981206 | |||||||
WBsf988112 | |||||||
WBsf221408 | |||||||
WBsf221409 | |||||||
WBsf221410 | |||||||
WBsf221411 | |||||||
WBsf221412 | |||||||
Experimental_info | RNAi_result (154) | ||||||
Expr_pattern | Chronogram1286 | ||||||
Expr6760 | |||||||
Expr8824 | |||||||
Expr1013402 | |||||||
Expr1031922 | |||||||
Expr1157630 | |||||||
Expr2014889 | |||||||
Expr2033124 | |||||||
Drives_construct | WBCnstr00003500 | ||||||
WBCnstr00013546 | |||||||
WBCnstr00035740 | |||||||
Construct_product | WBCnstr00013546 | ||||||
WBCnstr00035740 | |||||||
Microarray_results (19) | |||||||
Expression_cluster (156) | |||||||
Interaction (292) | |||||||
Map_info | Map | II | Position | -0.394252 | Error | 0.000796 | |
Positive | Positive_clone | T24H7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference (26) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |