WormBase Tree Display for Gene: WBGene00003939

WBGene00003939 Evidence: Person_evidence: WBPerson96
  SMap: S_parent: Sequence: CHROMOSOME_II
  Identity: Version: 1
    Name: CGC_name: pax-3 Person_evidence: WBPerson96
      Sequence_name: F27E5.2
      Molecular_name: F27E5.2
        F27E5.2.1
        CE35862
      Other_name: CELE_F27E5.2 Accession_evidence: NDB BX284602
      Public_name: pax-3
    DB_info: Database: AceView gene 2K439
        WormFlux gene WBGene00003939
        NDB locus_tag CELE_F27E5.2
        Panther gene CAEEL|WormBase=WBGene00003939|UniProtKB=G5ED66
          family PTHR45636
        NCBI gene 185022
        RefSeq protein NM_063788.3
        SwissProt UniProtAcc G5ED66
        TREEFAM TREEFAM_ID TF351610
        UniProt_GCRP UniProtAcc G5ED66
        OMIM gene 167410
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:33 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: pax
    Allele (109)
    Strain: WBStrain00028931
    RNASeq_FPKM (74)
    GO_annotation (16)
    Ortholog (46)
    Paralog (22)
    Structured_description: Concise_description: pax-3 encodes a divergent paired-like homeodomain protein that does not belong to the Q50, K50, or S50 classes; PAX-3 is required for locomotion and vulval development; pax-3(RNAi) animals have consistent Pvl and Unc phenotypes (as well as less consistent Bmd, Rup, and Stp phenotypes). Paper_evidence: WBPaper00005654
            WBPaper00006395
            WBPaper00012756
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in epidermal cell fate specification; gonad morphogenesis; and hemidesmosome assembly. Located in nucleus. Expressed in several structures, including AB lineage cell; E lineage cell; P9/10L; hypodermal cell; and tail. Human ortholog(s) of this gene implicated in alveolar rhabdomyosarcoma and congenital myopathy 19. Is an ortholog of human PAX7 (paired box 7). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0081351 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:8621)
      DOID:4051 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:8621)
  Molecular_info: Corresponding_CDS: F27E5.2
    Corresponding_CDS_history: F27E5.2:wp111
    Corresponding_transcript: F27E5.2.1
    Other_sequence (13)
    Associated_feature (18)
    Transcription_factor: WBTranscriptionFactor000298
  Experimental_info: RNAi_result (16)
    Expr_pattern (13)
    Drives_construct: WBCnstr00005879
      WBCnstr00005880
      WBCnstr00005881
      WBCnstr00005882
      WBCnstr00012916
      WBCnstr00014228
      WBCnstr00015305
      WBCnstr00015306
      WBCnstr00035784
    Construct_product: WBCnstr00035784
    Microarray_results (20)
    Expression_cluster (94)
    Interaction (139)
  Map_info: Map: II Position: 2.03217 Error: 0.043029
    Positive: Positive_clone: F27E5 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5093
    Pseudo_map_position
  Reference (18)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene