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WormBase Tree Display for Gene: WBGene00003922

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Name Class

WBGene00003922EvidenceCGC_data_submission
SMapS_parentSequenceC15H11
IdentityVersion1
NameCGC_namepas-1Person_evidenceWBPerson1551
Sequence_nameC15H11.7
Molecular_nameC15H11.7
C15H11.7.1
CE08184
Other_nameCELE_C15H11.7Accession_evidenceNDBBX284605
Public_namepas-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpas
Allele (24)
StrainWBStrain00036322
RNASeq_FPKM (74)
GO_annotation (15)
Contained_in_operonCEOP5416
Ortholog (43)
Paralog (13)
Structured_descriptionConcise_descriptionpas-1 encodes a type 6 alpha subunit of the 26S proteasome's 20S protease core particle (CP); PAS-1 is required for embryonic development and by homology, is predicted to comprise the outer rings of the proteasome and to play a role in selective degradation of ubiquitinated proteins during development; in vitro, PAS-1 interacts with VET-1, a coiled-coil domain-containing protein expressed in the early embryo and ATN-1, an alpha-actinin, in addition to other members of the proteasome.Paper_evidenceWBPaper00004888
WBPaper00005553
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to be involved in proteasomal protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome core complex, alpha-subunit complex. Human ortholog(s) of this gene implicated in myocardial infarction. Is an ortholog of human PSMA6 (proteasome 20S subunit alpha 6).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:5844Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9535)
Molecular_infoCorresponding_CDSC15H11.7
Corresponding_transcriptC15H11.7.1
Other_sequence (117)
Associated_featureWBsf234945
Experimental_infoRNAi_result (15)
Expr_patternExpr13736
Expr1021243
Expr1031855
Expr1144680
Expr2014740
Expr2032974
Microarray_results (21)
Expression_cluster (145)
Interaction (254)
Map_infoMapVPosition6.30322Error0.000935
PositivePositive_cloneC15H11Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00026640
WBPaper00029221
WBPaper00031906
WBPaper00038491
WBPaper00049828
WBPaper00055090
WBPaper00056008
WBPaper00056554
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene