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WormBase Tree Display for Gene: WBGene00003902

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Name Class

WBGene00003902SMapS_parentSequenceY106G6H
Identity (6)
Gene_infoBiotypeSO:0001217
Gene_classpab
Allele (47)
StrainWBStrain00036402
WBStrain00007709
RNASeq_FPKM (74)
GO_annotation (39)
Ortholog (59)
Paralog (15)
Structured_descriptionConcise_descriptionpab-1 encodes a polyadenylate-binding protein (i.e., poly(A)-binding protein, or PAB); pab-1 is essential for germline proliferation, regulation of adult lifespan, and normal body size; PAB-1 forms a complex with ATX-2, the C. elegans ataxin 2 ortholog, which is also required for germline development; PAB-1 has been successfully used as an epitope-tagged transgenic reagent for tissue-specific isolation of mRNAs.Paper_evidenceWBPaper00005068
WBPaper00005428
WBPaper00012788
WBPaper00012830
WBPaper00012882
WBPaper00012897
WBPaper00013003
WBPaper00024364
WBPaper00024924
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated07 Jul 2008 00:00:00
Automated_descriptionEnables mRNA binding activity. Involved in several processes, including gamete generation; positive regulation of reproductive process; and regulation of cell cycle. Located in P granule and P-body. Part of polysome. Expressed in intestine. Is an ortholog of several human genes including PABPC1 (poly(A) binding protein cytoplasmic 1); PABPC3 (poly(A) binding protein cytoplasmic 3); and PABPC4 (poly(A) binding protein cytoplasmic 4).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY106G6H.2
Corresponding_CDS_historyY106G6H.2b:wp274
Y106G6H.2c:wp274
Corresponding_transcriptY106G6H.2.1
Y106G6H.2.2
Y106G6H.2.3
Other_sequence (258)
Associated_feature (13)
Experimental_infoRNAi_result (45)
Expr_patternExpr8554
Expr13363
Expr1022819
Expr1031839
Expr1158811
Expr2014674
Expr2032907
Drives_constructWBCnstr00035807
Construct_product (13)
AntibodyWBAntibody00002359
WBAntibody00002494
WBAntibody00002700
WBAntibody00002921
Microarray_results (47)
Expression_cluster (180)
Interaction (595)
Map_infoMapIPosition5.02503Error0.008962
PositivePositive_cloneY106G6HInferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point5441
5711
Reference (46)
MethodGene