WormBase Tree Display for Gene: WBGene00003902

WBGene00003902 SMap: S_parent: Sequence: Y106G6H
  Identity: Version: 1
    Name: CGC_name: pab-1 Person_evidence: WBPerson1160
      Sequence_name: Y106G6H.2
      Molecular_name: Y106G6H.2
        Y106G6H.2.1
        CE20412
        Y106G6H.2.2
        Y106G6H.2.3
      Other_name: CELE_Y106G6H.2 Accession_evidence: NDB BX284601
      Public_name: pab-1
    DB_info: Database: AceView gene 1L10
        WormQTL gene WBGene00003902
        WormFlux gene WBGene00003902
        NDB locus_tag CELE_Y106G6H.2
        Panther gene CAEEL|WormBase=WBGene00003902|UniProtKB=Q9U302
          family PTHR24012
        NCBI gene 172920
        RefSeq protein NM_001383718.2
        TrEMBL UniProtAcc Q9U302
        UniProt_GCRP UniProtAcc Q9U302
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:33 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: pab
    Allele (47)
    Strain: WBStrain00036402
      WBStrain00007709
    RNASeq_FPKM (74)
    GO_annotation (39)
    Ortholog: WBGene00059858 Caenorhabditis remanei From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00025293 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00029486 Caenorhabditis briggsae From_analysis: OrthoMCL
      WBGene00143020 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00109656 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00109652 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
      WBGene00137004 Caenorhabditis japonica From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00144584 Caenorhabditis brenneri From_analysis: TreeFam
            WormBase-Compara
      CBOVI.g10111 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g15627 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP21.g5058 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g2871 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g19349 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g9678 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g4173 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g4555 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g5246 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g25593 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g15189 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00031.g1800 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_07908.g21171 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_09871.g22325 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-pab-1 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold475.g1698 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00140.g5433 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_05227 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_002367 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g01841 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g2747 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_10218000 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrI_pilon.g2038 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00264717 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00286480 Trichuris muris From_analysis: WormBase-Compara
      WBGene00301904 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000000967 Saccharomyces cerevisiae From_analysis: Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0265297 Drosophila melanogaster From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-030131-9663 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-030131-5836 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-030131-3238 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:8556 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:8557 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:8554 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:15797 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:31955 Homo sapiens From_analysis: Hieranoid
            OrthoFinder
            Panther
            PhylomeDB
      HGNC:13629 Homo sapiens From_analysis: OrthoFinder
            Panther
            PhylomeDB
      MGI:1349722 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1349723 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1914793 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:2136401 Mus musculus From_analysis: OrthoFinder
            Panther
            PhylomeDB
      MGI:2385206 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      MGI:3643087 Mus musculus From_analysis: Hieranoid
            OrthoFinder
            Panther
            PhylomeDB
      MGI:1922908 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:619838 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1310759 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1311201 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1559517 Rattus norvegicus From_analysis: Hieranoid
            OrthoFinder
            Panther
            PhylomeDB
      RGD:1563142 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1305015 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:1587661 Rattus norvegicus From_analysis: OrthoFinder
            Panther
            PhylomeDB
    Paralog (15)
    Structured_description: Concise_description: pab-1 encodes a polyadenylate-binding protein (i.e., poly(A)-binding protein, or PAB); pab-1 is essential for germline proliferation, regulation of adult lifespan, and normal body size; PAB-1 forms a complex with ATX-2, the C. elegans ataxin 2 ortholog, which is also required for germline development; PAB-1 has been successfully used as an epitope-tagged transgenic reagent for tissue-specific isolation of mRNAs. Paper_evidence: WBPaper00005068
            WBPaper00005428
            WBPaper00012788
            WBPaper00012830
            WBPaper00012882
            WBPaper00012897
            WBPaper00013003
            WBPaper00024364
            WBPaper00024924
          Curator_confirmed: WBPerson1843
            WBPerson567
          Date_last_updated: 07 Jul 2008 00:00:00
      Automated_description: Enables mRNA binding activity. Involved in several processes, including gamete generation; positive regulation of reproductive process; and regulation of cell cycle. Located in P granule and P-body. Part of polysome. Expressed in intestine. Is an ortholog of several human genes including PABPC1 (poly(A) binding protein cytoplasmic 1); PABPC3 (poly(A) binding protein cytoplasmic 3); and PABPC4 (poly(A) binding protein cytoplasmic 4). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y106G6H.2
    Corresponding_CDS_history: Y106G6H.2b:wp274
      Y106G6H.2c:wp274
    Corresponding_transcript: Y106G6H.2.1
      Y106G6H.2.2
      Y106G6H.2.3
    Other_sequence (258)
    Associated_feature (13)
  Experimental_info: RNAi_result (45)
    Expr_pattern: Expr8554
      Expr13363
      Expr1022819
      Expr1031839
      Expr1158811
      Expr2014674
      Expr2032907
    Drives_construct: WBCnstr00035807
    Construct_product (13)
    Antibody: WBAntibody00002359
      WBAntibody00002494
      WBAntibody00002700
      WBAntibody00002921
    Microarray_results (47)
    Expression_cluster (180)
    Interaction (595)
  Map_info: Map: I Position: 5.02503 Error: 0.008962
    Positive: Positive_clone: Y106G6H Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5441
        5711
  Reference (46)
  Method: Gene