WormBase Tree Display for Gene: WBGene00003888

WBGene00003888 SMap: S_parent: Sequence: R07G3
  Identity: Version: 2
    Name: CGC_name: osm-8 Paper_evidence: WBPaper00040819
          Person_evidence: WBPerson242
      Sequence_name: R07G3.6
      Molecular_name: R07G3.6
        R07G3.6.1
        CE50739
      Other_name: CELE_R07G3.6 Accession_evidence: NDB BX284602
      Public_name: osm-8
    DB_info: Database: WormFlux gene WBGene00003888
        NDB locus_tag CELE_R07G3.6
        NCBI gene 187684
        RefSeq protein NM_063194.8
        SwissProt UniProtAcc Q09423
        UniProt_GCRP UniProtAcc Q09423
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:33 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 25 Apr 2012 09:54:21 WBPerson2970 Event: Acquires_merge: WBGene00019942
              Name_change: Sequence_name: R07G3.6
      Acquires_merge: WBGene00019942
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: osm
    Allele (19)
    Legacy_information: [C.elegansII] n1518 : defective osmotic avoidance. NA1. [MT; JT]
    Strain: WBStrain00027074
      WBStrain00033230
    RNASeq_FPKM (74)
    GO_annotation: 00053788
      00053789
      00053790
      00053791
      00053792
    Ortholog (20)
    Structured_description: Concise_description: osm-8 encodes a mucin-like secreted protein with a PST (proline/serine/threonine) domain similar to the PST domain in human mucin, Muc2; osm-8 is a negative regulator of the osmotic stress response, mutants for osm-8 show inappropriate activation of physiological responses to osmotic stress; osm-8 acts through the hypodermally expressed transmembrane protein PTR-23 to activate osmosensitive gene expression, glycerol accumulation and other responses to osmotic stimuli; osm-8 is expressed in the hypodermis and is most likely secreted from the hypodermal apical membrane. Paper_evidence: WBPaper00038064
          Curator_confirmed: WBPerson324
          Date_last_updated: 21 Feb 2012 00:00:00
      Automated_description: Involved in regulation of gene expression and response to osmotic stress. Located in extracellular space. Expressed in hyp7 syncytium. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: R07G3.6
    Corresponding_CDS_history: R07G3.6:wp248
    Corresponding_transcript: R07G3.6.1
    Other_sequence: Dviv_isotig26472
      Dviv_isotig29429
    Associated_feature: WBsf650241
      WBsf223355
      WBsf223356
  Experimental_info: RNAi_result: WBRNAi00026059 Inferred_automatically: RNAi_primary
      WBRNAi00027434 Inferred_automatically: RNAi_primary
      WBRNAi00017565 Inferred_automatically: RNAi_primary
      WBRNAi00051501 Inferred_automatically: RNAi_primary
      WBRNAi00026060 Inferred_automatically: RNAi_primary
      WBRNAi00034724 Inferred_automatically: RNAi_primary
      WBRNAi00051503 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr11207
      Expr1031831
      Expr1155181
      Expr2014647
      Expr2032880
    Drives_construct: WBCnstr00018220
      WBCnstr00035812
    Construct_product: WBCnstr00035812
    Regulate_expr_cluster: WBPaper00035873:osm-8_regulated
    Microarray_results (18)
    Expression_cluster (170)
    Interaction: WBInteraction000504743
  Map_info: Map: II Position: 0.5056
    Positive: Positive_clone: R07G3 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 1361
      Pos_neg_data: 3715
        3716
  Reference (15)
  Method: Gene