WormBase Tree Display for Gene: WBGene00003837
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| WBGene00003837 | SMap | S_parent | Sequence | T01B11 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | oat-1 | |||||||
| Sequence_name | T01B11.7 | ||||||||
| Molecular_name | T01B11.7 | ||||||||
| T01B11.7.1 | |||||||||
| CE30160 | |||||||||
| Other_name | CELE_T01B11.7 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | oat-1 | ||||||||
| DB_info | Database | AceView | gene | 4J230 | |||||
| WormQTL | gene | WBGene00003837 | |||||||
| WormFlux | gene | WBGene00003837 | |||||||
| NDB | locus_tag | CELE_T01B11.7 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003837|UniProtKB=G5EDU0 | |||||||
| family | PTHR24064 | ||||||||
| NCBI | gene | 177649 | |||||||
| RefSeq | protein | NM_069041.6 | |||||||
| TrEMBL | UniProtAcc | G5EDU0 | |||||||
| UniProt_GCRP | UniProtAcc | G5EDU0 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | oat | ||||||||
| Allele (93) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00014764 | ||||||||
| 00014765 | |||||||||
| 00111879 | |||||||||
| 00111880 | |||||||||
| 00111881 | |||||||||
| Ortholog (90) | |||||||||
| Paralog (27) | |||||||||
| Structured_description | Concise_description | oat-1 encodes a transmembrane organic anion transporter; although loss of oat-1 activity via large-scale RNAi screens results in no obvious abnormalities, when expressed in mammalian cells OAT-1 can transport a variety of structurally diverse organic anions via an anion exchange mechanism that is functionally coupled to a sodium-coupled dicarboxylate transporter; by homology with mammalian OAT1 transporters, C. elegans OAT-1 is predicted to function in xenobiotic elimination. | Paper_evidence | WBPaper00003716 | |||||
| WBPaper00004424 | |||||||||
| WBPaper00005654 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 19 Jan 2005 00:00:00 | ||||||||
| Automated_description | Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Lynch syndrome and mismatch repair cancer syndrome. Is an ortholog of several human genes including SLC22A17 (solute carrier family 22 member 17); SLC22A6 (solute carrier family 22 member 6); and SLC22A8 (solute carrier family 22 member 8). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:3883 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16261) | ||||
| DOID:0112182 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16261) | ||||||
| Molecular_info | Corresponding_CDS | T01B11.7 | |||||||
| Corresponding_transcript | T01B11.7.1 | ||||||||
| Other_sequence (26) | |||||||||
| Associated_feature | WBsf1017850 | ||||||||
| WBsf230432 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00052074 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00017933 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00052075 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00034997 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00017932 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1013385 | ||||||||
| Expr1155705 | |||||||||
| Expr2014588 | |||||||||
| Expr2032821 | |||||||||
| Drives_construct | WBCnstr00035843 | ||||||||
| Construct_product | WBCnstr00035843 | ||||||||
| Microarray_results | SMD_6T01B11.7 | ||||||||
| SMD_T01B11.6 | |||||||||
| SMD_T01B11.7 | |||||||||
| 172063_x_at | |||||||||
| 172866_x_at | |||||||||
| 191435_s_at | |||||||||
| A_12_P103394 | |||||||||
| A_12_P140820 | |||||||||
| A_12_P140821 | |||||||||
| Aff_T01B11.6 | |||||||||
| Aff_T01B11.7 | |||||||||
| GPL13394_WBGene00003837 | |||||||||
| GPL13914_T01B11.7 | |||||||||
| GPL14144_T01B11.7_405-464_0.870_37_C | |||||||||
| GPL14144_T01B11.7_694-753_0.893_22_A | |||||||||
| GPL14144_T01B11.7_789-848_0.873_34_B | |||||||||
| GPL19516_CGZ0032508 | |||||||||
| GPL19516_CGZ0032509 | |||||||||
| GPL21109_T01B11.7.1 | |||||||||
| GPL3518_CE30160 | |||||||||
| GPL8304_CE_WBGene00003837_A | |||||||||
| GPL8673_T01B11_7P00224 | |||||||||
| GPL8673_T01B11_7P00611 | |||||||||
| GPL8673_T01B11_7P01070 | |||||||||
| GPL9450_T01B11.7 | |||||||||
| cea2.c.30736 | |||||||||
| Expression_cluster (167) | |||||||||
| Interaction (11) | |||||||||
| Map_info | Map | IV | Position | 3.83208 | Error | 0.002368 | |||
| Positive | Positive_clone | T01B11 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00003716 | ||||||||
| Remark | Sequence connection from [George RL, Ganapathy V] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
