WormBase Tree Display for Gene: WBGene00003828
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WBGene00003828 | Evidence | Paper_evidence | WBPaper00003957 | ||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | C07B5 | ||||||
Identity | Version | 1 | |||||||
Name | CGC_name | nuc-1 | Person_evidence | WBPerson261 | |||||
Sequence_name | C07B5.5 | ||||||||
Molecular_name | C07B5.5 | ||||||||
C07B5.5.1 | |||||||||
CE00895 | |||||||||
Other_name | CELE_C07B5.5 | Accession_evidence | NDB | BX284606 | |||||
Public_name | nuc-1 | ||||||||
DB_info | Database (12) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | nuc | ||||||||
Reference_allele | WBVar00143968 | ||||||||
Allele (36) | |||||||||
Legacy_information | e1392amber : major endodeoxyribonuclease reduced > 95%; condensed chromatin persists after programmed cell death DNA in intestinal lumen not degraded. ES1 ME3. NA3 (n887 (resembles e1392) n334 (weaker allele)). | ||||||||
See also e1392, n334, n887 | |||||||||
[C.elegansII] e1392amb : major endodeoxyribonuclease reduced >95%; condensed chromatin persists after programmed cell death DNA in intestinal lumen not degraded. ES1 ME3. OA2: n887 (resembles e1392), n334 (weaker allele). [Hedgecock et al. 1983; Ellis et al. 1991; MT] | |||||||||
Strain | WBStrain00027342 | ||||||||
WBStrain00004233 | |||||||||
WBStrain00004320 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (21) | |||||||||
Ortholog (43) | |||||||||
Paralog | WBGene00000799 | Caenorhabditis elegans | From_analysis | Panther | |||||
WormBase-Compara | |||||||||
WBGene00007056 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | The nuc-1 gene encodes a DNase II homolog similar to mammalian and Drosophila DNaseII enzymes and is required for DNA degradation during apoptosis as well as for degradation of dietary DNA during normal feeding; during apoptosis, NUC-1 functions in apoptotic cells at an intermediate stage of DNA degradation, after the killing step, but prior to cell-corpse engulfment. | Paper_evidence | WBPaper00003957 | |||||
WBPaper00005291 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Enables deoxyribonuclease II activity. Involved in apoptotic DNA fragmentation. Acts upstream of or within with a positive effect on negative regulation of antimicrobial peptide production. Located in lysosome. Expressed in body wall musculature; head; intestinal cell; and vulva. Is an ortholog of human DNASE2 (deoxyribonuclease 2, lysosomal) and DNASE2B (deoxyribonuclease 2 beta). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | C07B5.5 | |||||||
Corresponding_transcript | C07B5.5.1 | ||||||||
Other_sequence (24) | |||||||||
Associated_feature | WBsf648415 | ||||||||
WBsf648416 | |||||||||
WBsf663170 | |||||||||
WBsf663171 | |||||||||
WBsf663172 | |||||||||
WBsf1006465 | |||||||||
WBsf1023584 | |||||||||
WBsf236169 | |||||||||
WBsf236170 | |||||||||
Experimental_info | RNAi_result | WBRNAi00039986 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00063204 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00010375 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00087544 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00028623 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00007199 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr15882 | ||||||||
Expr1018429 | |||||||||
Expr1031803 | |||||||||
Expr1144064 | |||||||||
Expr2014522 | |||||||||
Expr2032761 | |||||||||
Drives_construct | WBCnstr00005863 | ||||||||
WBCnstr00005864 | |||||||||
WBCnstr00005865 | |||||||||
WBCnstr00005866 | |||||||||
WBCnstr00005871 | |||||||||
WBCnstr00005872 | |||||||||
WBCnstr00005873 | |||||||||
WBCnstr00020428 | |||||||||
WBCnstr00035848 | |||||||||
WBCnstr00042575 | |||||||||
Construct_product (13) | |||||||||
Microarray_results (21) | |||||||||
Expression_cluster (273) | |||||||||
Interaction (47) | |||||||||
WBProcess | WBbiopr:00000013 | ||||||||
Map_info | Map | X | Position | 1.41821 | Error | 0.022587 | |||
Well_ordered | |||||||||
Positive | Positive_clone | C07B5 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | 2_point | 166 | |||||||
188 | |||||||||
Multi_point | 282 | ||||||||
445 | |||||||||
643 | |||||||||
795 | |||||||||
3318 | |||||||||
4086 | |||||||||
4087 | |||||||||
4088 | |||||||||
4089 | |||||||||
4333 | |||||||||
Pos_neg_data | 659 | ||||||||
666 | |||||||||
Reference (93) | |||||||||
Method | Gene |