WormBase Tree Display for Gene: WBGene00003789
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| WBGene00003789 | SMap | S_parent | Sequence | K12D12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | npp-3 | Person_evidence | WBPerson1780 | |||||
| Sequence_name | K12D12.2 | ||||||||
| Molecular_name | K12D12.2 | ||||||||
| K12D12.2.1 | |||||||||
| CE02271 | |||||||||
| Other_name | CELE_K12D12.2 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | npp-3 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | npp | ||||||||
| Allele (170) | |||||||||
| Strain | WBStrain00036647 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (19) | |||||||||
| Ortholog (59) | |||||||||
| Structured_description | Concise_description | npp-3 encodes a nucleoporin that is a homolog of vertebrate Nup205; npp-3 is required for normal nuclear pore complex distribution in the nuclear envelope, nuclear exclusion of large non-nuclear macromolecules, chromatin condensation, proper mitotic spindle orientation, early embryonic viability, body integrity, and locomotion. | Paper_evidence | WBPaper00005654 | |||||
| WBPaper00006202 | |||||||||
| WBPaper00026966 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 08 Apr 2008 00:00:00 | ||||||||
| Automated_description | Predicted to be a structural constituent of nuclear pore. Involved in several processes, including establishment of localization in cell; positive regulation of nematode male tail tip morphogenesis; and regulation of cell cycle. Predicted to be located in nucleus. Predicted to be part of nuclear pore inner ring. Expressed in embryonic cell. Human ortholog(s) of this gene implicated in nephrotic syndrome type 13. Is an ortholog of human NUP205 (nucleoporin 205). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0080381 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:18658) | ||||
| Molecular_info | Corresponding_CDS | K12D12.2 | |||||||
| Corresponding_transcript | K12D12.2.1 | ||||||||
| Other_sequence | CRC06602_1 | ||||||||
| CJC11499_1 | |||||||||
| ACC13806_1 | |||||||||
| EX566231.1 | |||||||||
| CR03689 | |||||||||
| CBC16193_1 | |||||||||
| CBC01448_1 | |||||||||
| Acan_isotig08559 | |||||||||
| EY459769.1 | |||||||||
| EX556621.1 | |||||||||
| Associated_feature (11) | |||||||||
| Experimental_info | RNAi_result (12) | ||||||||
| Expr_pattern | Expr10099 | ||||||||
| Expr1014247 | |||||||||
| Expr1031775 | |||||||||
| Expr1154367 | |||||||||
| Expr2014388 | |||||||||
| Expr2032629 | |||||||||
| Drives_construct | WBCnstr00035866 | ||||||||
| Construct_product | WBCnstr00035866 | ||||||||
| Antibody | WBAntibody00002370 | ||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (129) | |||||||||
| Interaction (54) | |||||||||
| Map_info | Map | II | Position | 4.09903 | Error | 0.00412 | |||
| Positive | Positive_clone | K12D12 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (14) | |||||||||
| Remark | Sequence connection from [Askjaer P, Mattaj IW]. krb 13/11/01 | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
