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WormBase Tree Display for Gene: WBGene00003650

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Name Class

WBGene00003650EvidencePaper_evidenceWBPaper00003416
SMapS_parentSequenceF57A10
IdentityVersion1
NameCGC_namenhr-60Person_evidenceWBPerson600
Sequence_nameF57A10.5
Molecular_nameF57A10.5
F57A10.5.1
CE16151
Other_nameCELE_F57A10.5Accession_evidenceNDBBX284605
Public_namenhr-60
DB_infoDatabaseAceViewgene5Q252
WormQTLgeneWBGene00003650
WormFluxgeneWBGene00003650
NDBlocus_tagCELE_F57A10.5
PanthergeneCAEEL|WormBase=WBGene00003650|UniProtKB=O17898
familyPTHR24083
NCBIgene180059
RefSeqproteinNM_074529.4
SwissProtUniProtAccO17898
TREEFAMTREEFAM_IDTF321099
UniProt_GCRPUniProtAccO17898
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:32WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classnhr
Allele (71)
StrainWBStrain00032105
WBStrain00032123
RNASeq_FPKM (74)
GO_annotation (15)
Ortholog (31)
Paralog (42)
Structured_descriptionConcise_descriptionnhr-60 encodes a nuclear hormone receptor required for seam cell development, and for embryonic and early larval viability; NHR-60 has no obvious non-nematode orthologs, and is thus classified as 'supplementary'; NHR-60 is expressed throughout development in most cells from one-cell embryos to adults, and is noticeably enriched in seam cells and germline; NHR-60's germline enrichment suggests that it is maternally contributed to oocytes; subcellularly, NHR-60 is localized to the nuclear periphery; nhr-60 is transcribed in embryonic seam cell precursors, and in larval seam cells, pharyngeal gland cells, and uterine vulval uv1 cells; NHR-23 is required for nhr-60 transcription in seam cells but not in pharynx; a dominant-negative NHR-60 isoform displaces endogeneous NHR-60 from the nuclear periphery.Paper_evidenceWBPaper00003416
WBPaper00030774
Curator_confirmedWBPerson567
Date_last_updated27 Mar 2008 00:00:00
Automated_descriptionPredicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Located in nuclear envelope. Expressed in several structures, including VC neuron; pharyngeal gland cell; ray; seam cell; and uv1.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF57A10.5
Corresponding_transcriptF57A10.5.1
Other_sequenceMI07063
JI176107.1
MIC06343_1
Associated_featureWBsf978703
WBsf1002349
WBsf1021061
WBsf235086
WBsf235087
Transcription_factorWBTranscriptionFactor000272
Experimental_infoRNAi_resultWBRNAi00032996Inferred_automaticallyRNAi_primary
WBRNAi00077959Inferred_automaticallyRNAi_primary
WBRNAi00015860Inferred_automaticallyRNAi_primary
WBRNAi00077957Inferred_automaticallyRNAi_primary
WBRNAi00048799Inferred_automaticallyRNAi_primary
WBRNAi00077958Inferred_automaticallyRNAi_primary
WBRNAi00077956Inferred_automaticallyRNAi_primary
Expr_patternExpr8038
Expr8039
Expr8040
Expr8041
Expr1025577
Expr1031691
Expr1152551
Expr2014211
Expr2032452
Drives_constructWBCnstr00013072
WBCnstr00035970
Construct_productWBCnstr00035970
AntibodyWBAntibody00001268
WBAntibody00001269
WBAntibody00001437
Microarray_results (17)
Expression_cluster (76)
InteractionWBInteraction000031383
WBInteraction000358037
WBInteraction000401242
WBInteraction000429708
WBInteraction000502939
WBInteraction000540179
WBInteraction000541735
Map_infoMapVPosition8.81205Error0.020519
PositivePositive_cloneF57A10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5006
5343
Pseudo_map_position
ReferenceWBPaper00024846
WBPaper00025032
WBPaper00026048
WBPaper00027309
WBPaper00027468
WBPaper00030453
WBPaper00030774
WBPaper00042128
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene