WormBase Tree Display for Gene: WBGene00003638
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| WBGene00003638 | Evidence | Paper_evidence | WBPaper00003416 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| WBPaper00004181 | |||||||||
| SMap | S_parent | Sequence | ZK662 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | nhr-48 | Person_evidence | WBPerson600 | |||||
| Sequence_name | ZK662.3 | ||||||||
| Molecular_name (12) | |||||||||
| Other_name | CELE_ZK662.3 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | nhr-48 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:32 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | nhr | ||||||||
| Allele (172) | |||||||||
| Strain | WBStrain00000017 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Ortholog (37) | |||||||||
| Paralog (217) | |||||||||
| Structured_description | Concise_description | nhr-48 encodes a nuclear receptor that, along with daf-12 and nhr-8, comprise the C. elegans members of a conserved nuclear receptor subfamily that includes Drosophila HR96 and the vertebrate vitamin D, PXR, and CAR proteins; an nhr-48::gfp reporter is expressed in the pharyngeal gland in larvae and adults and in the spermatheca beginning in L4; weak hypodermal expression is also seen in some transgenic lines. | Paper_evidence | WBPaper00004181 | |||||
| WBPaper00006412 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 May 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including anterior gonad arm; pharyngeal gland cell; and spermatheca. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); autosomal recessive limb-girdle muscular dystrophy type 2B; carcinoma (multiple); and lung disease (multiple). Is an ortholog of human VDR (vitamin D receptor). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (53) | ||||||||
| Molecular_info | Corresponding_CDS | ZK662.3a | |||||||
| ZK662.3b | |||||||||
| ZK662.3c | |||||||||
| ZK662.3d | |||||||||
| Corresponding_CDS_history | ZK662.3:wp80 | ||||||||
| ZK662.3a:wp272 | |||||||||
| ZK662.3b:wp272 | |||||||||
| Corresponding_transcript | ZK662.3a.1 | ||||||||
| ZK662.3b.1 | |||||||||
| ZK662.3c.1 | |||||||||
| ZK662.3d.1 | |||||||||
| Other_sequence | ACC30960_1 | ||||||||
| EY465586.1 | |||||||||
| AS13263 | |||||||||
| CBC16456_1 | |||||||||
| JI166537.1 | |||||||||
| CRC04316_1 | |||||||||
| AE01982 | |||||||||
| JI221228.1 | |||||||||
| CR00423 | |||||||||
| Associated_feature (25) | |||||||||
| Transcription_factor | WBTranscriptionFactor000408 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00059624 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00063664 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00063665 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr2867 | ||||||||
| Expr13121 | |||||||||
| Expr14786 | |||||||||
| Expr1027283 | |||||||||
| Expr1031682 | |||||||||
| Expr1163029 | |||||||||
| Expr2014197 | |||||||||
| Expr2032438 | |||||||||
| Drives_construct | WBCnstr00010997 | ||||||||
| WBCnstr00035978 | |||||||||
| Construct_product | WBCnstr00021753 | ||||||||
| WBCnstr00035978 | |||||||||
| Microarray_results (31) | |||||||||
| Expression_cluster (101) | |||||||||
| Interaction (17) | |||||||||
| Map_info | Map | X | Position | 22.9404 | Error | 0.00227 | |||
| Positive | Positive_clone | ZK662 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4383 | |||||||
| 4524 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (14) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
