WormBase Tree Display for Gene: WBGene00003514
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| WBGene00003514 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | myo-2 | Person_evidence | WBPerson261 | |||||
| Sequence_name | T18D3.4 | ||||||||
| Molecular_name | T18D3.4 | ||||||||
| T18D3.4.1 | |||||||||
| CE31619 | |||||||||
| Other_name | CELE_T18D3.4 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | myo-2 | ||||||||
| DB_info | Database | AceView | gene | XN91 | |||||
| WormQTL | gene | WBGene00003514 | |||||||
| WormFlux | gene | WBGene00003514 | |||||||
| NDB | locus_tag | CELE_T18D3.4 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003514|UniProtKB=P12845 | |||||||
| family | PTHR45615 | ||||||||
| NCBI | gene | 181404 | |||||||
| RefSeq | protein | NM_077691.5 | |||||||
| SwissProt | UniProtAcc | P12845 | |||||||
| UniProt_GCRP | UniProtAcc | P12845 | |||||||
| OMIM | gene | 160710 | |||||||
| 160720 | |||||||||
| 160740 | |||||||||
| 160741 | |||||||||
| 160760 | |||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:32 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | myo | ||||||||
| Allele (116) | |||||||||
| Possibly_affected_by | WBVar02157816 | ||||||||
| Legacy_information | No mutations known. Pharyngeal myosin. | ||||||||
| [C.elegansII] NMK. Encodes pharyngeal myosin. [Dibb et al. 1989; Okkema and Fire 1994] | |||||||||
| Strain (1278) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (22) | |||||||||
| Ortholog (56) | |||||||||
| Paralog (21) | |||||||||
| Structured_description | Concise_description | myo-2 encodes a muscle-type specific myosin heavy chain isoform; myo-2 is expressed in pharyngeal muscle. | Paper_evidence | WBPaper00000129 | |||||
| WBPaper00001124 | |||||||||
| WBPaper00001807 | |||||||||
| WBPaper00002476 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| Date_last_updated | 21 Jan 2005 00:00:00 | ||||||||
| Automated_description | Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in muscle contraction and sarcomere organization. Predicted to be located in cytoplasm and myosin filament. Predicted to be part of muscle myosin complex. Expressed in neurons and pharynx. Human ortholog(s) of this gene implicated in several diseases, including congenital heart disease (multiple); distal myopathy 1; and intrinsic cardiomyopathy (multiple). Is an ortholog of several human genes including MYH1 (myosin heavy chain 1); MYH2 (myosin heavy chain 2); and MYH3 (myosin heavy chain 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (30) | ||||||||
| Molecular_info | Corresponding_CDS | T18D3.4 | |||||||
| Corresponding_CDS_history | T18D3.4:wp83 | ||||||||
| Corresponding_transcript | T18D3.4.1 | ||||||||
| Other_sequence (54) | |||||||||
| Associated_feature (24) | |||||||||
| Gene_product_binds | WBsf919639 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00053468 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00000326 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (30) | |||||||||
| Drives_construct (140) | |||||||||
| Construct_product | WBCnstr00010324 | ||||||||
| WBCnstr00015775 | |||||||||
| WBCnstr00018825 | |||||||||
| WBCnstr00018826 | |||||||||
| WBCnstr00018827 | |||||||||
| WBCnstr00018828 | |||||||||
| WBCnstr00018829 | |||||||||
| WBCnstr00018830 | |||||||||
| WBCnstr00036080 | |||||||||
| Antibody | WBAntibody00000013 | ||||||||
| Microarray_results (24) | |||||||||
| Expression_cluster (288) | |||||||||
| Interaction (174) | |||||||||
| Map_info | Map | X | Position | 7.10914 | Error | 0.00154 | |||
| Positive | Positive_clone | PGBC6S | |||||||
| T18D3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
| YK1044 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (195) | |||||||||
| Remark | Map X | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
