WormBase Tree Display for Gene: WBGene00003485
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| WBGene00003485 | SMap | S_parent | Sequence | W10G6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | mua-6 | Person_evidence | WBPerson1052 | |||||
| Sequence_name | W10G6.3 | ||||||||
| Molecular_name | W10G6.3 | ||||||||
| W10G6.3.1 | |||||||||
| CE18354 | |||||||||
| Other_name | Cel IF A2 | Accession_evidence | EMBL | X70835 | |||||
| CelIF a2 | |||||||||
| ifa-2 | |||||||||
| A2 | Paper_evidence | WBPaper00006137 | |||||||
| CELE_W10G6.3 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | mua-6 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:32 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | mua | ||||||||
| Allele (56) | |||||||||
| Legacy_information | [C.elegansII] rh85 : progressive paralysis, defective muscle attachments like Mua-1; poor growth; most homozygotes arrest as larvae; adults Egl; Smg suppressible. NA1. [NJ] | ||||||||
| Strain | WBStrain00028839 | ||||||||
| WBStrain00034473 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Ortholog (53) | |||||||||
| Paralog (12) | |||||||||
| Structured_description | Concise_description | mua-6 encodes an essential intermediate filament protein (MUA-6/IFA-2) that is coexpressed with the essential IF protein IFB-1; MUA-6 is required for hypodermal integrity and for lasting attachment of muscles to the body wall; MUA-6 is also required for normal positioning of excretory canals and muscles; MUA-6 forms heteropolymeric intermediate filaments in vitro with an equimolar mixture of IFB-1; mua-6 is transcribed from L1 larval to adult stages; MUA-6 resides in main body hypodermal desmosomes, but not in seam cells. | Paper_evidence | WBPaper00001981 | |||||
| WBPaper00004103 | |||||||||
| WBPaper00004661 | |||||||||
| WBPaper00004761 | |||||||||
| WBPaper00005492 | |||||||||
| WBPaper00006137 | |||||||||
| WBPaper00006210 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to be a structural constituent of cytoskeleton. Involved in cell-cell adhesion. Located in hemidesmosome. Expressed in hypodermis; touch receptor neurons; uterus; and ventral cord neurons. Human ortholog(s) of this gene implicated in partial lipodystrophy; primary autosomal recessive microcephaly; and progressive myoclonus epilepsy 9. Is an ortholog of human LMNB2 (lamin B2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111450 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||
| DOID:0070296 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||||
| DOID:0080299 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||||
| Molecular_info | Corresponding_CDS | W10G6.3 | |||||||
| Corresponding_transcript | W10G6.3.1 | ||||||||
| Other_sequence (76) | |||||||||
| Associated_feature | WBsf671428 | ||||||||
| WBsf1008482 | |||||||||
| WBsf1008483 | |||||||||
| WBsf1008484 | |||||||||
| WBsf1024760 | |||||||||
| WBsf1024761 | |||||||||
| WBsf1024762 | |||||||||
| WBsf238385 | |||||||||
| WBsf238386 | |||||||||
| Experimental_info | RNAi_result (22) | ||||||||
| Expr_pattern | Expr2259 | ||||||||
| Expr2768 | |||||||||
| Expr12514 | |||||||||
| Expr1031598 | |||||||||
| Expr1158649 | |||||||||
| Expr2013823 | |||||||||
| Expr2032063 | |||||||||
| Drives_construct | WBCnstr00010734 | ||||||||
| WBCnstr00010941 | |||||||||
| WBCnstr00036088 | |||||||||
| Construct_product | WBCnstr00010941 | ||||||||
| WBCnstr00036088 | |||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (246) | |||||||||
| Interaction (81) | |||||||||
| Map_info | Map | X | Position | 23.7205 | Error | 0.005559 | |||
| Positive | Positive_clone | W10G6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 2239 | |||||||
| 2240 | |||||||||
| 4658 | |||||||||
| Reference (40) | |||||||||
| Method | Gene |
