WormBase Tree Display for Gene: WBGene00003474
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WBGene00003474 | SMap | S_parent | Sequence | T08G5 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | mtl | ||||||
Allele (15) | |||||||
Legacy_information | [C.elegansII] NMK. Encodes 63 aa metallothionein; accumulates after exposure to CdCl2. mtl-1:lacZ expressed in intestine after cadmium treatment or heat shock. [Freedman et al. 1993] | ||||||
Strain | WBStrain00005079 | ||||||
WBStrain00005080 | |||||||
WBStrain00005081 | |||||||
WBStrain00005101 | |||||||
WBStrain00040877 | |||||||
WBStrain00035525 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00039557 | ||||||
00039558 | |||||||
00106045 | |||||||
00106046 | |||||||
00106267 | |||||||
00106268 | |||||||
Ortholog | WBGene00027389 | Caenorhabditis briggsae | From_analysis | OrthoMCL | |||
OMA | |||||||
WBGene00027390 | Caenorhabditis briggsae | From_analysis | OrthoMCL | ||||
Inparanoid_8 | |||||||
WormBase-Compara | |||||||
WBGene00151369 | Caenorhabditis brenneri | From_analysis | OMA | ||||
Inparanoid_8 | |||||||
WormBase-Compara | |||||||
WBGene00271681 | Caenorhabditis briggsae | From_analysis | WormBase-Compara | ||||
FL83_06429 | Caenorhabditis latens | From_analysis | WormBase-Compara | ||||
GCK72_020394 | Caenorhabditis remanei | From_analysis | WormBase-Compara | ||||
chrV_pilon.g16404 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00057046 | Caenorhabditis remanei | From_analysis | WormBase-Compara | ||||
Structured_description | Concise_description | mtl-2 encodes one of two C. elegans metallothioneins, small, cysteine-rich, metal-binding proteins; MTL-2 functions in metal detoxification and homeostasis and stress adaptation; in addition, mtl-2 plays a role in regulating growth and fertility; mtl-2 expression is induced in larval and adult intestinal cells following exposure to cadmium or heat shock; MTL-2 intestinal expression is dependent upon ELT-2, an intestine-specific GATA-type transcription factor; mtl-2 is downregulated by DAF-16 in daf-2 mutants. | Paper_evidence | WBPaper00001688 | |||
WBPaper00003700 | |||||||
WBPaper00004299 | |||||||
WBPaper00004381 | |||||||
WBPaper00005295 | |||||||
WBPaper00005976 | |||||||
WBPaper00028866 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 07 May 2007 00:00:00 | ||||||
Automated_description | Enables cadmium ion binding activity and zinc ion binding activity. Involved in response to cadmium ion and response to heat. Expressed in intestinal cell and intestine. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | T08G5.10 | |||||
Corresponding_transcript | T08G5.10.1 | ||||||
Other_sequence | CBC00932_1 | ||||||
CBC01514_2 | |||||||
FD517649.1 | |||||||
CBC01514_1 | |||||||
CJC01860_1 | |||||||
CSC00487_1 | |||||||
FD517704.1 | |||||||
Associated_feature | WBsf653359 | ||||||
WBsf919637 | |||||||
WBsf919638 | |||||||
WBsf982357 | |||||||
WBsf982358 | |||||||
WBsf234895 | |||||||
Experimental_info | RNAi_result (11) | ||||||
Expr_pattern | Expr1380 | ||||||
Expr1509 | |||||||
Expr3079 | |||||||
Expr1020789 | |||||||
Expr1156496 | |||||||
Expr2013808 | |||||||
Expr2032048 | |||||||
Drives_construct (15) | |||||||
Construct_product | WBCnstr00007972 | ||||||
WBCnstr00007973 | |||||||
WBCnstr00011119 | |||||||
WBCnstr00036093 | |||||||
Microarray_results (19) | |||||||
Expression_cluster (257) | |||||||
Interaction (39) | |||||||
WBProcess | WBbiopr:00000039 | ||||||
WBbiopr:00000050 | |||||||
WBbiopr:00000053 | |||||||
WBbiopr:00000096 | |||||||
Map_info | Map | V | Position | 6.07164 | Error | 0.009738 | |
Positive | Positive_clone | CR#MT2 | |||||
T08G5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | Multi_point | 4288 | |||||
4500 | |||||||
Pseudo_map_position | |||||||
Reference (74) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |