WormBase Tree Display for Gene: WBGene00003471

WBGene00003471 SMap: S_parent: Sequence: CHROMOSOME_I
  Identity: Version: 1
    Name: CGC_name: mtd-1 Person_evidence: WBPerson95
      Sequence_name: ZK337.5
      Molecular_name: ZK337.5
        ZK337.5.1
        CE24721
      Other_name: CELE_ZK337.5 Accession_evidence: NDB BX284601
      Public_name: mtd-1
    DB_info: Database: AceView gene 1P599
        WormQTL gene WBGene00003471
        WormFlux gene WBGene00003471
        NDB locus_tag CELE_ZK337.5
        NCBI gene 191285
        RefSeq protein NM_061214.9
        SwissProt UniProtAcc G5ECI1
        UniProt_GCRP UniProtAcc G5ECI1
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:32 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: mtd
    Allele (89)
    Strain: WBStrain00031389
    RNASeq_FPKM (74)
    GO_annotation: 00011867
      00011868
      00011869
      00011870
      00011871
    Ortholog (27)
    Structured_description: Concise_description: mtd-1 encodes a novel protein, with an N-terminal extracellular domain and a C-terminal transmembrane domain, that is expressed in touch receptor neurons; loss of mtd-1 function (by either RNAi or a deletion mutation) has no obvious phenotype alone, but specifically enhances touch insensitivity of the temperature-sensitive mec-6(u247). Paper_evidence: WBPaper00005559
          Curator_confirmed: WBPerson567
          Date_last_updated: 07 Jul 2004 00:00:00
      Automated_description: Involved in positive regulation of detection of mechanical stimulus involved in sensory perception of touch. Located in plasma membrane. Expressed in touch receptor neurons. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: ZK337.5
    Corresponding_transcript: ZK337.5.1
    Other_sequence: Name_isotig06195
      HBC04259_1
      EX910572.1
      CJC13596_1
      Hbac_isotig05294
      CBC08810_1
      EX916207.1
    Associated_feature: WBsf643878
      WBsf657153
  Experimental_info: RNAi_result: WBRNAi00059348 Inferred_automatically: RNAi_primary
      WBRNAi00022754 Inferred_automatically: RNAi_primary
      WBRNAi00038261 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr2285
      Expr1016086
      Expr1162775
      Expr2013802
      Expr2032042
    Drives_construct: WBCnstr00010751
      WBCnstr00036096
    Construct_product: WBCnstr00010751
      WBCnstr00036096
    Microarray_results (17)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032031:DConiospora_upregulated_OligoArray_24h
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_larva_enriched
      WBPaper00037950:all-neurons_larva_SelectivelyEnriched
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00040420:ALM_PLM_enriched
      WBPaper00040420:FLP_enriched
      WBPaper00044736:flat_dev_expression
      WBPaper00045417:128Q-huntingtin_downreglated
      WBPaper00046012:tdp-1(ok803)_upregulated
      WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
      WBPaper00048988:neuron_enriched
      WBPaper00048988:neuron_expressed
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050344:ASER-neuron_enriched
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050743:elli-1(sam-3)_downregulated
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(ot267)_upregulated
      WBPaper00053295:lin-22(ot269)_upregulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00054758:alg-1(gk204)_upregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin-Psora_downregulated
      WBPaper00055648:male-tail_expressed
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00058958:100mGy-irradiation-72h_upregulated
      WBPaper00059027:neuron-synapses_depleted
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060445:nfki-1(cer1)_downregulated_L4
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061340:ALM_BDU
      WBPaper00061340:ALM_PLM
      WBPaper00061340:PLM
      WBPaper00061466:nath-10(icb99)_downregulated
      WBPaper00061466:nath-10(icb102)_downregulated
      WBPaper00061527:mtd-1-mec-18
      WBPaper00061651:ALM_enriched
      WBPaper00061651:AVM_enriched
      WBPaper00061651:PLM_enriched
      WBPaper00061651:PVM_enriched
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00061995:mter-4(syb3662syb3403)_downregulated
      WBPaper00062103:neuron_enriched
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062167:mbl-1(tm1563)_downregulated
      WBPaper00062197:TRN_enriched
      WBPaper00064005:starvation_downregulated_N2_mRNA
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064716:paraquat_downregulated
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065623:67
      WBPaper00065841:20_0
      WBPaper00065841:20_1
      WBPaper00065841:20_2
      WBPaper00065841:54_0
      WBPaper00065841:70_0
      WBPaper00065841:75_0
      WBPaper00065841:137_0
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00030839:Embryo_Pan_Neuronal
      WBPaper00030839:Larval_Pan_Neuronal
      WBPaper00031532:Larva_Pan_Neuronal_Enriched
      WBPaper00036286:Pattern_C
      WBPaper00038060:SUMO-1_downregulated
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-exposed_51h
      WBPaper00042258:DA1877_upregulated_GravidAdult
    Interaction (12)
  Map_info: Map: I Position: 29.1761 Error: 0.091432
    Positive: Positive_clone: ZK337 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4499
    Pseudo_map_position
  Reference: WBPaper00005559
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene