Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00003464

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00003464SMapS_parentSequenceF32B6
IdentityVersion1
NameCGC_namemsp-77Person_evidenceWBPerson680
Sequence_nameF32B6.6
Molecular_nameF32B6.6
F32B6.6.1
CE09861
Other_nameCELE_F32B6.6Accession_evidenceNDBBX284604
Public_namemsp-77
DB_infoDatabaseAceViewgene4K659
WormQTLgeneWBGene00003464
WormFluxgeneWBGene00003464
NDBlocus_tagCELE_F32B6.6
PanthergeneCAEEL|WormBase=WBGene00003464|UniProtKB=Q9TVW5
familyPTHR22920
NCBIgene177844
RefSeqproteinNM_069380.5
SwissProtUniProtAccQ9TVW5
UniProt_GCRPUniProtAccQ9TVW5
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:32WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classmsp
AlleleWBVar01500079
WBVar01856404
WBVar01498996
WBVar01499925
WBVar00433032
WBVar00934603
WBVar00934604
WBVar00934605
WBVar01500245
Legacy_information[C.elegansII] NMK. Encodes MSP (16kD); defines cluster of 3 genes, 3 pseudogenes. [Ward et al. (1988); BA]
RNASeq_FPKM (74)
GO_annotation00096811
00096812
00096813
00096814
00096815
00096816
00096817
00096818
Ortholog (32)
Paralog (50)
Structured_descriptionConcise_descriptionmsp-77 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.Paper_evidenceWBPaper00001023
WBPaper00002143
WBPaper00003113
WBPaper00004591
WBPaper00005670
Curator_confirmedWBPerson324
Date_last_updated17 May 2005 00:00:00
Automated_descriptionInvolved in oocyte maturation; positive regulation of MAPK cascade; and positive regulation of smooth muscle contraction. Predicted to be located in cytoplasm; cytoskeleton; and pseudopodium. Expressed in gonad; oocyte; and sperm.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF32B6.6
Corresponding_transcriptF32B6.6.1
Other_sequence (36)
Associated_featureWBsf228898
Experimental_infoRNAi_result (20)
Expr_patternExpr3417
Expr1012537
Expr1150000
Expr2013789
Expr2032027
Drives_constructWBCnstr00036103
Construct_productWBCnstr00036103
AntibodyWBAntibody00000037
WBAntibody00000038
WBAntibody00000854
WBAntibody00000855
WBAntibody00000856
WBAntibody00000857
WBAntibody00000858
Microarray_resultsSMD_F32B6.6
Aff_F32B6.6
GPL14144_F32B6.6_48-107_0.926_1_A
GPL3518_CE09861
GPL8673_F32B6_6P00018
Expression_cluster (204)
Interaction (217)
Map_infoMapIVPosition4.4394Error0.000573
PositivePositive_cloneC01D10
F32B6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00001023
WBPaper00004591
WBPaper00014039
WBPaper00024312
WBPaper00028730
WBPaper00040308
WBPaper00057218
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene