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WormBase Tree Display for Gene: WBGene00003430

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Name Class

WBGene00003430SMapS_parentSequenceR05F9
IdentityVersion1
NameCGC_namemsp-32Person_evidenceWBPerson680
Sequence_nameR05F9.3
Molecular_nameR05F9.3
R05F9.3.1
CE52855
Other_nameCELE_R05F9.3Accession_evidenceNDBBX284602
Public_namemsp-32
DB_infoDatabaseAceViewgene2F189
WormQTLgeneWBGene00003430
WormFluxgeneWBGene00003430
NDBlocus_tagCELE_R05F9.3
PanthergeneCAEEL|WormBase=WBGene00003430|UniProtKB=P53018
familyPTHR22920
NCBIgene191709
RefSeqproteinNM_001381404.1
SwissProtUniProtAccP53018
UniProt_GCRPUniProtAccP53018
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:31WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classmsp
Allele (21)
Legacy_information[C.elegansII] NMK. Encodes MSP (16kD); msp-152 cluster. [Ward et al. (1988); BA]
RNASeq_FPKM (74)
GO_annotation00047989
00047990
00047991
00047992
00047993
Ortholog (35)
Paralog (52)
Structured_descriptionConcise_descriptionmsp-32 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-32 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the msp family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes; msp-32 expression is upregulated in animals containing a mutation in C01G5.6, which encodes the C. elegans Ddi1/Vsm1 homolog and is required for normal synaptogenesis.Paper_evidenceWBPaper00001023
WBPaper00002143
WBPaper00004280
WBPaper00004591
WBPaper00005670
WBPaper00040085
Curator_confirmedWBPerson1843
WBPerson324
Date_last_updated16 Aug 2011 00:00:00
Automated_descriptionPredicted to be located in cytoplasm; cytoskeleton; and pseudopodium. Expressed in gonad; oocyte; and sperm.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSR05F9.3
Corresponding_CDS_historyR05F9.3:wp268
Corresponding_transcriptR05F9.3.1
Other_sequence (65)
Experimental_infoRNAi_result (11)
Expr_patternExpr3417
Expr1014283
Expr1155007
Expr2013773
Expr2032010
Drives_constructWBCnstr00036122
Construct_productWBCnstr00036122
AntibodyWBAntibody00000037
WBAntibody00000038
WBAntibody00000854
WBAntibody00000855
WBAntibody00000856
WBAntibody00000857
WBAntibody00000858
Microarray_results (18)
Expression_cluster (89)
Interaction (220)
Map_infoMapIIPosition-2.93824Error0.003799
PositivePositive_cloneR05F9Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00001023
WBPaper00015440
WBPaper00016429
WBPaper00024312
WBPaper00024704
WBPaper00040085
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene