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WormBase Tree Display for Gene: WBGene00003426

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Name Class

WBGene00003426SMapS_parentSequenceF36H12
IdentityVersion1
NameCGC_namemsp-19Person_evidenceWBPerson680
Sequence_nameF36H12.7
Molecular_nameF36H12.7
F36H12.7.1
CE02806
Other_nameCELE_F36H12.7Accession_evidenceNDBBX284604
Public_namemsp-19
DB_infoDatabaseAceViewgene4G25
WormQTLgeneWBGene00003426
WormFluxgeneWBGene00003426
NDBlocus_tagCELE_F36H12.7
PanthergeneCAEEL|WormBase=WBGene00003426|UniProtKB=P53017
familyPTHR22920
NCBIgene177305
RefSeqproteinNM_001380219.1
SwissProtUniProtAccP53017
UniProt_GCRPUniProtAccP53017
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:31WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classmsp
AlleleWBVar00276507
WBVar01499365
WBVar00909457
WBVar01499754
WBVar01499395
WBVar01499396
WBVar00424881
WBVar01499242
WBVar01499633
WBVar01500245
Legacy_information[C.elegansII] NMK. Encodes MSP (16kD); msp-113 cluster. [Ward et al. (1988); BA]
RNASeq_FPKM (74)
GO_annotation00047984
00047985
00047986
00047987
00047988
Ortholog (22)
Paralog (50)
Structured_descriptionConcise_descriptionmsp-19 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-19 has a homolog in C. briggsae as predicted by the Wobble Aware Bulk Aligner (WABA); the msp gene family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.Paper_evidenceWBPaper00001023
WBPaper00002143
WBPaper00004280
WBPaper00004591
WBPaper00005670
Curator_confirmedWBPerson324
Date_last_updated26 Apr 2005 00:00:00
Automated_descriptionPredicted to be located in cytoplasm; cytoskeleton; and pseudopodium. Expressed in gonad; oocyte; and sperm.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF36H12.7
Corresponding_transcriptF36H12.7.1
Other_sequenceGW407950.1
GW409550.1
HC04637
GW411381.1
PTC01347_1
GW407605.1
Associated_featureWBsf228280
Experimental_infoRNAi_result (18)
Expr_patternExpr3417
Expr1150418
Expr2013772
Expr2032008
Drives_constructWBCnstr00036124
Construct_productWBCnstr00036124
AntibodyWBAntibody00000037
WBAntibody00000038
WBAntibody00000854
WBAntibody00000855
WBAntibody00000856
WBAntibody00000857
WBAntibody00000858
Microarray_resultsSMD_F36H12.7
SMD_F36H12.7:2
Aff_F36H12.7
GPL13394_WBGene00003426
GPL13914_F36H12.7
GPL8673_F36H12_7P00044
Expression_cluster (205)
SAGE_tagSAGE:gtggatcaactccaagtStrandAntisense
SAGE:tggagttctcgacccaaStrandSense
SAGE:gtggatcaacStrandAntisense
SAGE:tggagttctcStrandSense
Interaction (190)
Map_infoMapIVPosition1.58398Error0.000697
PositivePositive_cloneF36H12Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00001023
WBPaper00001024
WBPaper00015440
WBPaper00024312
WBPaper00041549
WBPaper00057218
Remarkremoved from gmap IV 1.61 [jah/sdm 5/99
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene