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WormBase Tree Display for Gene: WBGene00003411

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Name Class

WBGene00003411SMapS_parentSequenceCHROMOSOME_X
IdentityVersion1
NameCGC_namemrp-5Person_evidenceWBPerson490
Sequence_nameF14F4.3
Molecular_nameF14F4.3
F14F4.3.1
CE23650
Other_nameCELE_F14F4.3Accession_evidenceNDBBX284606
Public_namemrp-5
DB_infoDatabaseAceViewgeneXP558
WormQTLgeneWBGene00003411
WormFluxgeneWBGene00003411
NDBlocus_tagCELE_F14F4.3
PanthergeneCAEEL|WormBase=WBGene00003411|UniProtKB=G5EE72
familyPTHR24223
NCBIgene181587
RefSeqproteinNM_078078.4
SwissProtUniProtAccG5EE72
UniProt_GCRPUniProtAccG5EE72
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:31WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classmrp
Allele (124)
StrainWBStrain00002784
WBStrain00036722
RNASeq_FPKM (74)
GO_annotation (16)
Ortholog (41)
ParalogWBGene00000477Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003407Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003408Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003409Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003410Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003412Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003414Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003413Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionThe mrp-5 gene encodes a homolog of the human gene CFTR, which when mutated leads to cystic fibrosis (OMIM:219700).Paper_evidenceWBPaper00004424
WBPaper00004637
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnables ABC-type vitamin B12 transporter activity. Involved in cobalamin transport. Predicted to be located in membrane. Expressed in several structures, including body wall musculature; hypodermis; intestine; muscle cell; and pharynx. Human ortholog(s) of this gene implicated in pancreatic cancer. Is an ortholog of human ABCC12 (ATP binding cassette subfamily C member 12) and ABCC5 (ATP binding cassette subfamily C member 5).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:1793Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:56)
Molecular_infoCorresponding_CDSF14F4.3
Corresponding_CDS_historyF14F4.3a:wp252
Corresponding_transcriptF14F4.3.1
Other_sequence (48)
Associated_feature (16)
Experimental_infoRNAi_result (15)
Expr_pattern (11)
Drives_constructWBCnstr00003311
WBCnstr00011353
WBCnstr00013720
WBCnstr00019478
WBCnstr00019480
WBCnstr00036131
Construct_productWBCnstr00019479
WBCnstr00019480
WBCnstr00036131
Microarray_results (23)
Expression_cluster (188)
Interaction (42)
Map_infoMapXPosition21.5778Error0.006227
PositivePositive_cloneF14F4Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (20)
RemarkSequence connection from [Sheps JA, Baillie DL] [040902 ck1]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene