WormBase Tree Display for Gene: WBGene00003391
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| WBGene00003391 | SMap | S_parent | Sequence | F52C9 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | mog-3 | Person_evidence | WBPerson320 | |||||
| Sequence_name | F52C9.7 | ||||||||
| Molecular_name | F52C9.7 | ||||||||
| F52C9.7.1 | |||||||||
| CE04619 | |||||||||
| F52C9.7.2 | |||||||||
| Other_name | CELE_F52C9.7 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | mog-3 | ||||||||
| DB_info | Database | WormFlux | gene | WBGene00003391 | |||||
| NDB | locus_tag | CELE_F52C9.7 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003391|UniProtKB=G5EBT5 | |||||||
| family | PTHR16196 | ||||||||
| NCBI | gene | 175730 | |||||||
| RefSeq | protein | NM_065733.7 | |||||||
| TREEFAM | TREEFAM_ID | TF320801 | |||||||
| TrEMBL | UniProtAcc | G5EBT5 | |||||||
| UniProt_GCRP | UniProtAcc | G5EBT5 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:31 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 14 Aug 2012 17:01:26 | WBPerson2970 | Event | Acquires_merge | WBGene00018677 | ||||
| Name_change | Sequence_name | F52C9.7 | |||||||
| Acquires_merge | WBGene00018677 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | mog | ||||||||
| Allele (40) | |||||||||
| Legacy_information | [Graham PL] ts Mog. At 25 degrees, most hermaphrodites make only sperm, 13% make ooids. At 15 degrees fertile but Mel. Also Mel if feminized by fem-3. NA1. | ||||||||
| [C.elegansII] q74 : ts Mog, at 25C , most hermaphrodites make only sperm, 13% make ooids. At 15 degrees fertile but Mel. Also Mel if feminized by fem-3. NA1. [Graham et al. 1993] | |||||||||
| Strain | WBStrain00022521 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Contained_in_operon | CEOP3284 | ||||||||
| Ortholog (22) | |||||||||
| Structured_description | Concise_description | mog-3 encodes a conserved nuclear protein which shares homology to a yeast splicing factor: MOG-3 contains two motifs in its N-terminus that are fully conserved from yeasts to vertebrates; necessary for oogenesis and robust germ line proliferation; mog-3 and gld-3 functions synergistically to promote meiosis progression; MOG-3, MEP-1 and CIR-1 belong to single complex; MOG-3 interacts with N-terminus but not the conserved N-terminus motifs of MEP-1 and that is necessary and sufficient for nuclear zinc-finger MEP-1 protein binding; MOG-3 interacts with CIR-1 and with MEP-1 via two distinct domains; MOG proteins represses fem-3 via MEP-1 binding; mog-3 is expressed at steady state levels throughout embryogenesis and during larval development when hermaphrodites switch to oogenesis and also in adults; MOG-3 is a ubiquitous nuclear protein mainly expressed in oocyte lineage; similar to CIR-1, MOG-3 is also detected in somatic and meiotic nuclei as well as developing L4 vulva. | Paper_evidence | WBPaper00036278 | |||||
| Curator_confirmed | WBPerson12884 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 19 May 2011 00:00:00 | ||||||||
| Automated_description | Involved in feminization of hermaphroditic germ-line and meiotic cell cycle. Located in nucleus. Expressed in germ line. Is an ortholog of human CWC25 (CWC25 spliceosome associated protein homolog). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F52C9.7 | |||||||
| Corresponding_transcript | F52C9.7.1 | ||||||||
| F52C9.7.2 | |||||||||
| Other_sequence (27) | |||||||||
| Associated_feature | WBsf645162 | ||||||||
| WBsf645163 | |||||||||
| WBsf658932 | |||||||||
| WBsf992353 | |||||||||
| WBsf992354 | |||||||||
| WBsf224912 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00110123 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00108014 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00015390 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00047954 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00005621 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00007714 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00032602 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00067605 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00077843 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr9043 | ||||||||
| Expr9044 | |||||||||
| Expr9045 | |||||||||
| Expr9046 | |||||||||
| Expr1031563 | |||||||||
| Expr1151775 | |||||||||
| Expr2013650 | |||||||||
| Expr2031884 | |||||||||
| Drives_construct | WBCnstr00013687 | ||||||||
| WBCnstr00036144 | |||||||||
| Construct_product | WBCnstr00013687 | ||||||||
| WBCnstr00036144 | |||||||||
| Antibody | WBAntibody00002140 | ||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (91) | |||||||||
| Interaction (13) | |||||||||
| Map_info | Map | III | Position | -1.83752 | |||||
| Positive | Positive_clone | F52C9 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 2791 | |||||||
| Pos_neg_data | 7381 | ||||||||
| Reference (16) | |||||||||
| Remark | data extracted from Graham, Schedl & Kimble 1993 | ||||||||
| Method | Gene |
