WormBase Tree Display for Gene: WBGene00003173
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WBGene00003173 | SMap | S_parent | Sequence | C50H2 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | mec-9 | Person_evidence | WBPerson95 | |||||
Sequence_name | C50H2.3 | ||||||||
Molecular_name | C50H2.3a | ||||||||
C50H2.3a.1 | |||||||||
CE05481 | |||||||||
C50H2.3b | |||||||||
CE08916 | |||||||||
C50H2.3b.1 | |||||||||
Other_name | CELE_C50H2.3 | Accession_evidence | NDB | BX284605 | |||||
Public_name | mec-9 | ||||||||
DB_info | Database | WormQTL | gene | WBGene00003173 | |||||
WormFlux | gene | WBGene00003173 | |||||||
NDB | locus_tag | CELE_C50H2.3 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00003173|UniProtKB=Q18761 | |||||||
family | PTHR24039 | ||||||||
NCBI | gene | 179382 | |||||||
RefSeq | protein | NM_001269224.3 | |||||||
NM_001269225.3 | |||||||||
TREEFAM | TREEFAM_ID | TF316678 | |||||||
TrEMBL | UniProtAcc | G3MVG9 | |||||||
Q18761 | |||||||||
UniProt_GCRP | UniProtAcc | Q18761 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:31 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | mec | ||||||||
Allele (119) | |||||||||
Legacy_information | u27amber : touch insensitive lethargic. ES2 ME2. NA > 20 (e1494 u164amber etc.). | ||||||||
[C.elegansII] u27amb : touch insensitive lethargic. ES2 ME2. OA>30: e1494, e1852, u164amb etc. Cloned: 2 kb and 3 kb transcripts, transpliced to SL1 and SL2, encode protein with Kunitztype serine protease inhibitor domains, EGF-like repeats. mec-9:GFP expressed in touch cells and PVD (3kb promoter) or more extensively (2kb promoter). [Chalfie and Au 1989; Huang and Chalfie 1994; TU] | |||||||||
Strain | WBStrain00032822 | ||||||||
WBStrain00004348 | |||||||||
WBStrain00006234 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (15) | |||||||||
Ortholog (21) | |||||||||
Paralog (31) | |||||||||
Structured_description | Concise_description | mec-9 encodes a predicted extracellular protein containing six EGF-like repeats,five Kunitz-type protease inhibitor domains, and a glutamic acid-rich region possibly involved in protein-protein interactions; mec-9 encodes two proteins, only one of which, MEC-9L, appears to be required for normal mechanosensory response to gentle touch and proper functioning of the touch receptor neurons; mec-9 interacts genetically with mec-5, which encodes a unique C. elegans collagen secreted by the hypodermis; MEC-9L is expressed and secreted by the touch receptor neurons. | Paper_evidence | WBPaper00002379 | |||||
WBPaper00005666 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Predicted to enable calcium ion binding activity and serine-type endopeptidase inhibitor activity. Involved in positive regulation of multicellular organismal process and response to mechanical stimulus. Predicted to be located in extracellular region. Expressed in PVDL; PVDR; head neurons; touch receptor neurons; and ventral cord neurons. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | C50H2.3a | |||||||
C50H2.3b | |||||||||
Corresponding_CDS_history | C50H2.3a:wp144 | ||||||||
C50H2.3b:wp144 | |||||||||
Corresponding_transcript | C50H2.3a.1 | ||||||||
C50H2.3b.1 | |||||||||
Other_sequence (14) | |||||||||
Associated_feature | WBsf669266 | ||||||||
WBsf669267 | |||||||||
WBsf669268 | |||||||||
WBsf1001008 | |||||||||
WBsf1020239 | |||||||||
WBsf234297 | |||||||||
Experimental_info | RNAi_result | WBRNAi00042982 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00012263 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00067621 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00112683 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00089014 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr268 | ||||||||
Expr1026433 | |||||||||
Expr1146947 | |||||||||
Expr2013503 | |||||||||
Expr2031737 | |||||||||
Drives_construct | WBCnstr00004795 | ||||||||
WBCnstr00036197 | |||||||||
Construct_product | WBCnstr00036197 | ||||||||
Microarray_results (23) | |||||||||
Expression_cluster (161) | |||||||||
Interaction (29) | |||||||||
Map_info | Map | V | Position | 2.2108 | Error | 0.000399 | |||
Well_ordered | |||||||||
Positive | Inside_rearr | eDf1 | |||||||
Positive_clone | C50H2 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||||
Negative | Negative_clone | F15H4 | |||||||
Mapping_data (3) | |||||||||
Reference (49) | |||||||||
Method | Gene |