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WormBase Tree Display for Gene: WBGene00003159

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Name Class

WBGene00003159EvidenceCGC_data_submission
SMapS_parentSequenceF32D1
IdentityVersion1
NameCGC_namemcm-7Person_evidenceWBPerson1160
Sequence_nameF32D1.10
Molecular_nameF32D1.10
F32D1.10.1
CE09874
Other_nameCELE_F32D1.10Accession_evidenceNDBBX284605
Public_namemcm-7
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:30WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classmcm
Allele (80)
Possibly_affected_byWBVar02158446
StrainWBStrain00001281
WBStrain00001282
WBStrain00001670
WBStrain00001671
RNASeq_FPKM (74)
GO_annotation (31)
Ortholog (39)
ParalogWBGene00003154Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003155Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003156Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003157Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003158Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionmcm-7 encodes the C. elegans ortholog of the MCM7 member of the MCM complex, a hexameric protein complex required for the initiation and regulation of DNA replication.Paper_evidenceWBPaper00040645
Curator_confirmedWBPerson1843
Date_last_updated13 Feb 2012 00:00:00
Automated_descriptionPredicted to enable single-stranded DNA binding activity. Predicted to contribute to single-stranded DNA helicase activity. Involved in MCM complex assembly; embryo development; and mitotic sister chromatid segregation. Predicted to be located in nucleus. Predicted to be part of MCM complex. Expressed in several structures, including anchor cell; intestine; tail; uterine epithelial cell; and vulval precursor cell. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and pancreatic ductal carcinoma. Is an ortholog of human MCM7 (minichromosome maintenance complex component 7).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:3587Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6950)
DOID:684Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6950)
Molecular_infoCorresponding_CDSF32D1.10
Corresponding_transcriptF32D1.10.1
Other_sequence (32)
Associated_featureWBsf646750
WBsf646751
WBsf977406
WBsf977407
WBsf977408
WBsf977409
WBsf231660
WBsf231661
Experimental_infoRNAi_result (13)
Expr_pattern (11)
Drives_constructWBCnstr00002176
WBCnstr00002177
WBCnstr00004246
WBCnstr00036210
Construct_productWBCnstr00022504
WBCnstr00036210
AntibodyWBAntibody00002756
Microarray_results (21)
Expression_cluster (275)
Interaction (239)
Map_infoMapVPosition-5.85076Error0.013093
PositivePositive_cloneF32D1Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (16)
RemarkSequence connection from [Kim SK]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene