mat-1 encodes the C. elegans ortholog of the APC/C (anaphase promoting complex/cyclosome) subunit CDC27/APC3; mat-1 activity is required for progression through the meiotic and mitotic cell cycles; mat-1 and APC/C activity is also required for regulating the abundance of GLR-1 glutamate receptors in the ventral nerve cord.
Involved in asymmetric cell division; cortical granule exocytosis; and polarity specification of anterior/posterior axis. Predicted to be located in cytoplasm. Predicted to be part of anaphase-promoting complex. Is an ortholog of human CDC27 (cell division cycle 27).