WormBase Tree Display for Gene: WBGene00003056
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WBGene00003056 | SMap | S_parent | Sequence | CHROMOSOME_X | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | lon | ||||||
Reference_allele | WBVar00143398 | ||||||
Allele (213) | |||||||
Legacy_information (2) | |||||||
Strain (224) | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (19) | |||||||
Ortholog (25) | |||||||
Structured_description | Concise_description | lon-2 encodes a member of the glypican family of heparan sulfate proteoglycans; during development, lon-2 activity is required in the hypodermis for negative regulation of the DBL-1/BMP signaling pathway that regulates body length; genetic analyses indicate that lon-2 functions upstream of dbl-1, and in vitro studies show that LON-2 can bind mammalian BMP2, suggesting that LON-2 may directly interact with DBL-1 to negatively regulate DBL-1/BMP signaling; in addition to expression in hypodermis, LON-2 is expressed strongly in the intestine, particularly the anterior and posterior cells; LON-2 localizes to the cell surface. | Paper_evidence | WBPaper00029002 | |||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 24 Jan 2007 00:00:00 | ||||||
Automated_description | Enables growth factor binding activity. Involved in several processes, including negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; regulation of cell migration; and regulation of mesodermal cell fate specification. Located in cell surface. Expressed in hypodermis and intestine. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | C39E6.1 | |||||
Corresponding_CDS_history | C39E6.1:wp107 | ||||||
Corresponding_transcript | C39E6.1.1 | ||||||
Other_sequence (6) | |||||||
Associated_feature (15) | |||||||
Experimental_info | RNAi_result (23) | ||||||
Expr_pattern | Expr4651 | ||||||
Expr4652 | |||||||
Expr12191 | |||||||
Expr1011265 | |||||||
Expr1031435 | |||||||
Expr1146202 | |||||||
Expr2013244 | |||||||
Expr2031475 | |||||||
Drives_construct | WBCnstr00012150 | ||||||
WBCnstr00012151 | |||||||
WBCnstr00021097 | |||||||
WBCnstr00021479 | |||||||
WBCnstr00036259 | |||||||
Construct_product | WBCnstr00012151 | ||||||
WBCnstr00021471 | |||||||
WBCnstr00021474 | |||||||
WBCnstr00021479 | |||||||
WBCnstr00036259 | |||||||
Microarray_results (21) | |||||||
Expression_cluster (142) | |||||||
Interaction (24) | |||||||
Map_info | Map | X | Position | -6.74013 | Error | 0.007834 | |
Well_ordered | |||||||
Positive | Inside_rearr | mnDp30 | |||||
yDp4 | |||||||
Positive_clone | C39E6 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
F43C9 | |||||||
Negative | Outside_rearr | mcDf2 | |||||
Mapping_data | 2_point | 154 | |||||
158 | |||||||
159 | |||||||
161 | |||||||
162 | |||||||
164 | |||||||
165 | |||||||
166 | |||||||
167 | |||||||
168 | |||||||
169 | |||||||
170 | |||||||
171 | |||||||
172 | |||||||
173 | |||||||
174 | |||||||
175 | |||||||
176 | |||||||
283 | |||||||
286 | |||||||
288 | |||||||
299 | |||||||
374 | |||||||
377 | |||||||
397 | |||||||
414 | |||||||
427 | |||||||
428 | |||||||
434 | |||||||
475 | |||||||
624 | |||||||
1829 | |||||||
3148 | |||||||
3150 | |||||||
3384 | |||||||
3634 | |||||||
3635 | |||||||
3731 | |||||||
4456 | |||||||
4467 | |||||||
4570 | |||||||
6103 | |||||||
6110 | |||||||
6111 | |||||||
6119 | |||||||
6122 | |||||||
6135 | |||||||
6172 | |||||||
6173 | |||||||
6187 | |||||||
7041 | |||||||
7100 | |||||||
7125 | |||||||
7126 | |||||||
7127 | |||||||
7128 | |||||||
7129 | |||||||
Multi_point (150) | |||||||
Pos_neg_data (31) | |||||||
Landmark_gene | |||||||
Reference (155) | |||||||
Remark | sequence wsa incorrectly given as F43C9.3 | ||||||
Method | Gene |