WormBase Tree Display for Gene: WBGene00002827
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| WBGene00002827 | SMap | S_parent | Sequence | C29E6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | let-653 | Person_evidence | WBPerson36 | |||||
| Sequence_name | C29E6.1 | ||||||||
| Molecular_name | C29E6.1a | ||||||||
| C29E6.1a.1 | |||||||||
| CE40548 | |||||||||
| C29E6.1b | |||||||||
| CE37323 | |||||||||
| C29E6.1c | |||||||||
| CE05332 | |||||||||
| C29E6.1b.1 | |||||||||
| C29E6.1c.1 | |||||||||
| Other_name | CELE_C29E6.1 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | let-653 | ||||||||
| DB_info | Database | AceView | gene | 4M655 | |||||
| WormQTL | gene | WBGene00002827 | |||||||
| WormFlux | gene | WBGene00002827 | |||||||
| NDB | locus_tag | CELE_C29E6.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00002827|UniProtKB=Q27394 | |||||||
| family | PTHR47327 | ||||||||
| NCBI | gene | 178120 | |||||||
| RefSeq | protein | NM_001268665.4 | |||||||
| NM_001026165.7 | |||||||||
| NM_001026166.5 | |||||||||
| SwissProt | UniProtAcc | Q27394 | |||||||
| TREEFAM | TREEFAM_ID | TF318269 | |||||||
| UniProt_GCRP | UniProtAcc | Q27394 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:29 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | let | ||||||||
| Laboratory | BC | ||||||||
| Reference_allele | WBVar00242198 | ||||||||
| Allele (88) | |||||||||
| Legacy_information | Early larval e | ||||||||
| Lethal arrest stage is late L1 to early L2. | |||||||||
| See also s1733 | |||||||||
| [Marra MA] Developmental arrest stage 7 days after egg lay at room temperature: s2270 homozygote = L2 larva with a vacuole anterior to lower pharyngeal bulb. s2270/sDf10 = L1 larva with a vacuole anterior to lower pharyngeal bulb. | |||||||||
| [Marra MA] Developmental arrest stage 7 days after egg lay at room temperature: s2377 homozygote = Sterile adult. s2377/sDf10 = L2 larva with a vacuole anterior to lower pharyngeal bulb | |||||||||
| [C.elegansII] s1733 : early larval lethal, arrest stage is late L1 to early L2; cystic excretory canals. OA2: s2270 (homozygote arrests L2 with vacuole anterior to posterior pharyngeal bulb,hemizygote arrests L1), s2377 (homozygote sterile adult, hemizygote arrests L2). Cloned: encodes predicted 694 aa secreted protein, with features characteristic of mucin glycoproteins. [Jones and Baillie 1995; BC; NJ] | |||||||||
| Complementation_data | [Marra MA] s2270 fails to complement let-653(s1733). | ||||||||
| [Marra MA] s2377 fails to complement let-653(s2270). s2377 complements let-653(s1733). | |||||||||
| Strain | WBStrain00000664 | ||||||||
| WBStrain00051077 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (21) | |||||||||
| Ortholog (33) | |||||||||
| Paralog (14) | |||||||||
| Structured_description | Concise_description | let-653 encodes a mucin-like protein similar to the highly glycosylated mucins secreted by the apical surface of epithelia and believed to provide a protective barrier to exposed cellular surfaces; LET-653 is required for viability, locomotion, and for maintaining the tubular epithelial structure of the excretory cell canals. | Paper_evidence | WBPaper00001522 | |||||
| WBPaper00002328 | |||||||||
| WBPaper00005485 | |||||||||
| WBPaper00005654 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | A structural constituent of cuticle. Involved in several processes, including cuticle pattern formation; embryonic ectodermal digestive tract morphogenesis; and regulation of developmental process. Located in apical plasma membrane; extracellular space; and supramolecular fiber. Expressed in excretory duct cell; excretory socket cell; rectal epithelial cell; and vulval cell. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C29E6.1a | |||||||
| C29E6.1b | |||||||||
| C29E6.1c | |||||||||
| Corresponding_CDS_history | C29E6.1:wp131 | ||||||||
| C29E6.1a:wp167 | |||||||||
| Corresponding_transcript | C29E6.1a.1 | ||||||||
| C29E6.1b.1 | |||||||||
| C29E6.1c.1 | |||||||||
| Other_sequence (13) | |||||||||
| Associated_feature | WBsf660769 | ||||||||
| WBsf997988 | |||||||||
| WBsf997989 | |||||||||
| WBsf229216 | |||||||||
| Experimental_info | RNAi_result (18) | ||||||||
| Expr_pattern | Chronogram509 | ||||||||
| Expr5376 | |||||||||
| Expr13008 | |||||||||
| Expr13009 | |||||||||
| Expr15950 | |||||||||
| Expr1016864 | |||||||||
| Expr1031364 | |||||||||
| Expr1145484 | |||||||||
| Expr2013069 | |||||||||
| Expr2031301 | |||||||||
| Drives_construct | WBCnstr00002332 | ||||||||
| WBCnstr00036319 | |||||||||
| WBCnstr00038392 | |||||||||
| WBCnstr00039173 | |||||||||
| Construct_product | WBCnstr00036319 | ||||||||
| WBCnstr00038392 | |||||||||
| WBCnstr00039173 | |||||||||
| Microarray_results (28) | |||||||||
| Expression_cluster (220) | |||||||||
| Interaction (23) | |||||||||
| Map_info | Map | IV | Position | 5.36564 | Error | 0.003548 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | C29E6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| C46F3 | |||||||||
| F47H9 | |||||||||
| ZK822 | |||||||||
| Mapping_data | Multi_point | 4854 | |||||||
| 4821 | |||||||||
| 5253 | |||||||||
| Pos_neg_data (29) | |||||||||
| Reference (36) | |||||||||
| Method | Gene |
