WormBase Tree Display for Gene: WBGene00002368

WBGene00002368 SMap: S_parent: Sequence: K08E7
  Identity: Version: 1
    Name: CGC_name: let-99 Person_evidence: WBPerson533
      Sequence_name: K08E7.3
      Molecular_name: K08E7.3
        K08E7.3.1
        CE06147
      Other_name: CELE_K08E7.3 Accession_evidence: NDB BX284604
      Public_name: let-99
    DB_info: Database: AceView gene 4N335
        WormQTL gene WBGene00002368
        WormFlux gene WBGene00002368
        NDB locus_tag CELE_K08E7.3
        Panther gene CAEEL|WormBase=WBGene00002368|UniProtKB=Q21341
          family PTHR16206
        NCBI gene 178210
        RefSeq protein NM_070006.4
        SwissProt UniProtAcc Q21341
        TREEFAM TREEFAM_ID TF352206
        UniProt_GCRP UniProtAcc Q21341
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:27 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info (12)
  Molecular_info: Corresponding_CDS: K08E7.3
    Corresponding_transcript: K08E7.3.1
    Other_sequence: CR09932
      CRC00926_1
    Associated_feature: WBsf660821
      WBsf660822
      WBsf229308
  Experimental_info: RNAi_result (12)
    Expr_pattern: Chronogram1102
      Expr2256
      Expr4507
      Expr4508
      Expr1016659
      Expr1031353
      Expr1154006
      Expr2013081
      Expr2031313
    Drives_construct: WBCnstr00004437
      WBCnstr00004940
      WBCnstr00012068
      WBCnstr00019544
      WBCnstr00036329
    Construct_product: WBCnstr00004940
      WBCnstr00010005
      WBCnstr00012068
      WBCnstr00019544
      WBCnstr00036329
    Antibody: WBAntibody00000564
      WBAntibody00000702
      WBAntibody00002081
    Microarray_results (23)
    Expression_cluster: WBPaper00029359_1280
      WBPaper00029359_1304
      WBPaper00029359_1444
      WBPaper00029359_1497
      WBPaper00029359_1504
      WBPaper00029359_1604
      WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:germline-precursors_embryo_enriched
      WBPaper00037950:germline-precursors_embryo_SelectivelyEnriched
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00040560:hpl-2_L3_upregulated
      WBPaper00041071:spe-44_upregulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:rising_dev_expression
      WBPaper00044760:germline_specific
      WBPaper00044786:emr-1(gk119)_downregulated
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Oogenic
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00046012:tdp-1(ok803)_downregulated
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046805:csr-1(RNAi)_upregulated_Set1
      WBPaper00048611:MnCl2_downregulated
      WBPaper00048762:FOG-3_associated
      WBPaper00048988:neuron_expressed
      WBPaper00049498:npr-1(ur89)_regulated_6
      WBPaper00049942:HeatShock_upregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00049954:BPA_downregulated
      WBPaper00049954:BPS_downregulated
      WBPaper00050193:met-2(n4256)set-25(n5021)_upregulated_L1
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050522:mafr-1(tm6082)_downregulated
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:intestine_enriched
      WBPaper00050990:intestine_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051265:F1_morc-1(tm6048)_downregulated
      WBPaper00051265:F4_morc-1(tm6048)_upregulated
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:PGCs_enriched_NuGen
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
      WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_downregulated
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055354:Rapamycin-Allantoin_upregulated
      WBPaper00055354:Rapamycin_upregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056165:MINA-1_interacting_mRNA
      WBPaper00056290:hsp-6(mg585)_downregulated
      WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056826:hmc_biased
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057288:Cold_upregulated_transcript
      WBPaper00058598:mex-3(eu149)_downregulated
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058691:set-2(bn129)_downregulated
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00058886:anp-1(ok608)_downregulated
      WBPaper00059027:neuron-synapses_enriched
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00059739:hira-1(gk835598)_upregulated_L1
      WBPaper00059739:hira-1(gk835598)_upregulated_L4
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060445:ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060871:M.humicola-infection_48h_regulated
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061203:spr-1(ok2144)_downregulated
      WBPaper00061340:AVJ
      WBPaper00061340:rect_D
      WBPaper00061340:RID
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061527:let-99_22121-B0238.9_11154
      WBPaper00061527:let-99_22239-such-1
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062446:nhr-8(hd117)_downregulated
      WBPaper00062715:blmp-1(s71)_downregulated
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00064871:hypoxia_upregulated_F2
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065984:pals-17(syb3980)_upregulated
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4489_group_2
      cgc4489_group_16
      WBPaper00025032:cluster_1
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00032165:A_to_C_transit_decreased
      WBPaper00034757:down_by_oxidative_stress
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036123:Fluoranthene_regulated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_B
      WBPaper00040876:mir-35_upregulated
      WBPaper00040963:TA300_down
      WBPaper00041002:HF_3d_0.2mM_Down
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_UVC-exposed_24h
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00048563:L1_DD_enriched
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00051387:Triclosan_downregulated
      WBPaper00055435:AuNPs_downregulated
      WBPaper00056330:mrps-5(RNAi)_downregulated
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc5767]:cluster_1
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_MD_pd(53_min)
      [cgc5767]:expression_class_SM
      [cgc5767]:expression_class_SMD
      [cgc6390]:Cluster_E
      [cgc6390]:oogenesis-enriched
      [cgc6390]:spermatogenesis-enriched
    Interaction (224)
    WBProcess: WBbiopr:00000017
  Map_info: Map: IV Position: 6.02566 Error: 0.007381
    Well_ordered
    Positive: Positive_clone: C13H6
        K08E7 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: 2_point: 3321
      Multi_point: 1280
        1283
        4415
        4162
        5595
      Pos_neg_data (11)
  Reference (75)
  Remark: [BC Lab] Essential gene. Phenotype of homozygous s1201 is a maternal effect lethal.
  Method: Gene